A subset of medulloblastoma tumors briefly stopped growing or disappeared entirely during treatment with vismodegib; St. Jude Children’s Hospital led the Pediatric Brain Tumor Consortium trials in children and adults.
A team led by Klaus Schulten of the University of Illinois at Urbana-Champaign used the OLCF’s Titan to achieve a milestone in the field of biomolecular simulation, modeling a complete photosynthetic organelle of the bacteria Rhodobacter sphaeroides in atomic detail. The project, a 100-million atom spherical chromatophore, is the first of its kind, giving scientists a system-level understanding of a fundamental biological process based on all-atom precision.
Race and education shape employment outcomes for U.S.- and foreign-born blacks in surprising ways.
With U.S. Nuclear Regulatory Commission support, researchers at the Department of Energy’s Oak Ridge National Laboratory have devised a system that will help facilitate safe transportation of spent nuclear fuel.
A Vanderbilt research team has successfully created a mechanical wrist less than 1/16th of an inch thick -- small enough to use in needlescopic surgery, the least invasive form of minimally invasive surgery.
Researchers led by St. Jude scientists have discovered evidence for such characteristic features of malignant masses by analyzing the health records of 131 patients seen at St. Jude and Le Bonheur Children’s Hospital.
For the first time, researchers at the Department of Energy’s Oak Ridge National Laboratory have produced arrays of semiconductor junctions in arbitrary patterns within a single, nanometer-thick semiconductor crystal.
Poisonous spiders thrive in many temperate areas of the United States, and knowing how to identify them and treat venomous spider bites is essential, said Suparna Kumar, M.D., a certified specialist in poison information at the Tennessee Poison Control Center at Vanderbilt University Medical Center.
Middle Tennessee State University and the Tennessee Chamber of Commerce & Industry have partnered to launch the Tennessee Business Barometer, a new quarterly index capturing the mood and outlook of business leaders statewide through online surveys. The index consists of a core set of 17 questions, with the overall index score computed by adding the percentage of favorable responses to each question and subtracting the percentage of negative responses.
ORNL study demonstrates economic value of variable flow heat pumps; New catalyst provides potential solution to meet emissions challenges; ORNL, UK researchers working to develop cleaner crude oil; New climate data easily accessed at Data.gov
Small companies in the advanced manufacturing, transportation and building sectors have a new opportunity to partner with the Department of Energy’s Oak Ridge National Laboratory.
Viruses, not bacteria, are the most commonly detected respiratory pathogens in U.S. adults hospitalized with pneumonia, according to a New England Journal of Medicine study released today and conducted by researchers at Centers for Disease Control and Prevention (CDC) and hospitals in Chicago and Nashville, including Vanderbilt University Medical Center.
With temperatures holding steady in the upper 90s and even reaching 100 degrees this week, doctors at Vanderbilt University Medical Center are urging Middle Tennesseans to take extra precautions to avoid heat-related illnesses.
Vanderbilt University Medical Center (VUMC), the Human Vaccines Project and the International AIDS Vaccine Initiative (IAVI) are pleased to announce that VUMC has become the Project’s first scientific hub.
Groundbreaking work at two Department of Energy national laboratories has confirmed plutonium’s magnetism, which scientists have long theorized but have never been able to experimentally observe.
Vanderbilt University Medical Center has received a five-year, $12.8 million grant from the federal government to develop better ways to predict how patients will respond to the drugs they’re given.
Applying mild electrical stimulation to an area of the brain associated with cognitive control helps people with schizophrenia recognize errors and adjust their behavior to avoid them.
Vanderbilt University Medical Center’s James Crowe, M.D., Ann Scott Carell Professor and director of the Vanderbilt Vaccine Center, and his team are reporting the first large panel of antibody treatments against the chikungunya virus in the current issue of Cell Host and Microbe.
In an effort to further the commercial viability of cellulosic ethanol, a team led by ORNL’s Jeremy Smith used the Titan supercomputer to model the interaction of lignin and hemicellulose in the plant cell wall of a genetically modified aspen tree. The team’s conclusion—that hydrophobic, or water repelling, lignin binds less with hydrophilic, or water attracting, hemicellulose—points researchers toward a promising way to engineer better plants for biofuel. Published in the November 2014 edition of Physical Chemistry Chemical Physics, the results add context to experiments conducted by researchers at DOE’s BioEnergy Science Center, who demonstrated that genetic modification of lignin can boost the amount of biofuel derived from plant material without compromising the structural integrity of the plant.
Robert Edwards, a researcher and senior staff member at the Jefferson Lab (JLAB), is the principal investigator for a team researching the energy spectrum of exotic meson resonances. The main goal of Edwards’ ALCC project is give theoretical underpinnings to the 12-GeV upgrade project and Glue-X photon detector set to open in JLAB’s new HallD.
Researchers at Vanderbilt University and the National University of Singapore have determined the structure of a human monoclonal antibody which, in an animal model, strongly neutralizes a type of the potentially lethal dengue virus.
By growing two types of stem cells in a “3-D culture” and measuring their ability to produce retinal cells, a team lead by St. Jude Children’s Research Hospital researchers has found one cell type to be better at producing retinal cells. The research not only reveals which stem cell type might be better for treating retinal degeneration, but it also demonstrates a standardized method for quantifying the effectiveness of different stem cells for such therapies.
Nancy J. Dudney, Lonnie J. Love and David C. Radford have been named Corporate Fellows at the Department of Energy's Oak Ridge National Laboratory. The Corporate Fellow designation recognizes the researchers' significant accomplishments and continuing leadership in their scientific, engineering and technological fields.
Building technology researchers at DOE’s Oak Ridge National Laboratory collaborated with Dow to evaluate a new product invented by Dow that significantly reduces air leakage and helps to make residential and commercial buildings more energy efficient.
Eating a healthy diet was linked with a lower risk of dying from heart disease, stroke, cancer or other diseases among a population of low-income individuals living in the Southeastern U.S., according to research led by Vanderbilt University investigators. Nearly two-thirds of the participants in the study were African-American.
Fireworks and the Fourth of July can be a dangerous mix. Doctors at Vanderbilt University Medical Center urge caution with consumer fireworks and suggest leaving these displays to the experts. Vanderbilt doctors annually treat burns and eye injuries and even see patients with hearing loss due to fireworks usage.
Vanderbilt chemists Brian Bachmann and John McLean have shown that creating bacterial "fight clubs" is an effective way to discover natural biomolecules with the properties required for new drugs.
Researchers have developed a new method to manipulate a wide range of materials and their behavior using only a handful of helium ions.
It took marine sponges millions of years to perfect their spike-like structures, but research mimicking these formations may soon alter how industrial coatings and 3-D printed to additively manufactured objects are produced.
Scientists at St. Jude Children’s Research Hospital have discovered how an immune system protein, called AIM2 (Absent in Melanoma 2), plays a role in determining the aggressiveness of colon cancer. They found that AIM2 deficiency causes uncontrolled proliferation of intestinal cells.
Surgeons could know while their patients are still on the operating table if a tissue is cancerous, according to researchers from the Department of Energy's Oak Ridge National Laboratory and Brigham and Women’s Hospital/Harvard Medical School.
A new experiment shows that auditory melodies can enhance a musician's visual awareness of written music, particularly when the two match.
A new study led by Vanderbilt University Medical Center investigators found new diagnoses of prostate cancer in the U.S. declined 28 percent in the year following the draft recommendation from the United States Preventive Services Task Force (USPSTF) against routine PSA screening for men. The new research, led by first author Daniel Barocas, M.D., MPH, assistant professor of Urological Surgery and Medicine, was posted online in the June 15 issue of The Journal of Urology in advance of publication.
A series of immersive virtual reality experiments has confirmed that the human brain’s internal navigation system works in the same fashion as the grid cell system recently found in other mammals.
The Oak Ridge National Laboratory will open its doors July 14-15 for its “Explore ORNL” conference designed to introduce the region’s business community to the lab’s world-class R&D facilities and expertise.
The Vanderbilt Audiology Clinic is teaming up with the nonprofit organization MusiCares to provide free, custom earplugs for musicians at Bonnaroo and the CMA Music Festival.
Shift changes and movements of patients between different parts of a hospital are vulnerable times when mistakes are made, and a study from Vanderbilt University offers suggestions to offset the risk.
Hyundai Motor Company and the Department of Energy’s Oak Ridge National Laboratory have signed an agreement intended to strengthen the automaker’s U.S. research and development portfolio.
Biofuels pioneer Mascoma LLC and the Department of Energy's BioEnergy Science Center have developed a revolutionary strain of yeast that could help significantly accelerate the development of biofuels from nonfood plant matter.
This itch-causing plant pest, along with its cohorts poison oak and poison sumac, cause more common allergic reactions than any other source, said Renee Miller, R.N., a certified specialist in poison information at the Tennessee Poison Center at Vanderbilt University Medical Center.
Scientists at CERN’s Large Hadron Collider started recording data from the highest-energy particle collisions achieved on Earth. This new data will enable an international collaboration to study the Higgs boson, search for dark matter and develop a more complete understanding of the laws of nature. Oak Ridge National Laboratory led an equipment upgrade for LHC’s A Large Ion Collider Experiment (ALICE), which aims to learn more about conditions of the early universe.
Vanderbilt researchers have made the world’s smallest spirals and found they have unique optical properties that are nearly impossible to counterfeit if they were added to identity cards, currency and other objects.
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