Researchers at the Johns Hopkins University School of Medicine have mapped variation in human stem cells that explains how cells of an individual may shape a unique “developmental dance” at the molecular level, thereby controlling how the brain and body are created.
Open Disparities Narrowing Among Patients Undergoing Blood Stem Cell Transplant, Roswell Park Study Reveals configuration options Historically, some patients with blood cancers have been less likely than others to receive stem cell transplant, also known as bone marrow transplant.
UTHealth Houston has enrolled the first patient in the Southeastern United States into a national Phase I/II clinical trial testing whether a neural cell therapy product can help inhibit the abnormal electrical activity that leads to an epileptic seizure.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
Researchers at the National Institutes of Health (NIH) and their collaborators have identified a protein, known as RNF114, that reverses cataracts, a clouding of the eye’s lens that occurs commonly in people as they age.
According to researchers at The University of Texas MD Anderson Cancer Center, 80% of patients with previously untreated or relapsed/refractory advanced-phase chronic myeloid leukemia (CML) – including both accelerated or myeloid blast phases of the disease – or Philadelphia chromosome-positive acute myeloid leukemia (AML) achieved a bone marrow remission when treated with a novel combination of decitabine, venetoclax and ponatinib.
The Cedars-Sinai Board of Governors Regenerative Medicine Institute is creating a resource laboratory to help advance stem cell-based technologies throughout Cedars-Sinai and across California.
An Iowa State University research team has discovered when and why inflammatory signaling affects the formation of blood stem cells in embryos, which will benefit efforts to develop lab-grown, patient-derived stem cell transfusions to treat blood disorders. The promising advancement in regenerative medicine could eliminate the need for bone marrow transplants.
With newly awarded funding from the National Science Foundation, researchers at the University of California, Irvine and the Keck School of Medicine of USC will seek to revolutionize the treatment of neurological diseases through intelligent biocomputing. The four-year, $2 million grant is part of NSF’s Emerging Frontiers in Research and Innovation program, which funds cutting-edge science pushing the boundaries of human knowledge.
In regenerative medicine, the isolation of mesenchymal stromal cells (MSCs) from the adipose tissue’s stromal vascular fraction (SVF) is a critical area of study. Our review meticulously examines the isolation process of MSCs, starting wi
Peripheral nerve injury (PNI) is a common neurological disorder and complete functional recovery is difficult to achieve. In recent years, bone marrow mesenchymal stem cells (BMSCs) have emerged as ideal seed cells for PNI treatment due to
In this editorial, we delved into the article titled “Cellular preconditioning and mesenchymal stem cell ferroptosis.” This groundbreaking study underscores a pivotal discovery: Ferroptosis, a type of programmed cell death, drastically
In regenerative medicine, the isolation of mesenchymal stromal cells (MSCs) from the adipose tissue’s stromal vascular fraction (SVF) is a critical area of study. Our review meticulously examines the isolation process of MSCs, starting wi
This letter addresses the review titled “Wharton’s jelly mesenchymal stem cells: Future regenerative medicine for clinical applications in mitigation of radiation injury”. The review highlights the regenerative potential of Wharton’
Non-alcoholic fatty liver disease (NAFLD) is a pressing global health concern that is associated with metabolic syndrome and obesity. On the basis of the insights provided by Jiang et al, this editorial presents an exploration of the potent
BACKGROUNDPulmonary fibrosis is one of the main reasons for the high mortality rate among acute respiratory distress syndrome (ARDS) patients. Mesenchymal stromal cell-derived microvesicles (MSC-MVs) have been shown to exert antifibrotic ef
The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists led by Ulrich Technau from the University of Vienna have now identified possible candidates for multipotent stem cells in the sea anemone for the first time. These stem cells are regulated by evolutionary highly conserved genes, which in humans are usually only active in the formation of egg and sperm cells, but give ancient animal phyla such as cnidarians a high degree of regenerative capacity to even escape ageing. The results are currently being published in Science Advances and could also provide insights into the human ageing process in the future.
Researchers at Washington University School of Medicine in St. Louis describe the dramatic changes within nerve cells that make regeneration possible. Such findings could inspire the development of new therapies for spinal cord injuries in people.