Scientists at the Icahn School of Medicine at Mount Sinai, Sema4, and collaborating institutions today published results of an in-depth, multi-omics approach to characterizing the immune component of inflammatory bowel disease (IBD).
How did the gut, the skin and musculature evolve? This question concerns scientists for more than a century. Through the investigation of the embryonic development of sea anemones, a very old animal lineage, researchers from the University of Vienna have now come to conclusions which challenge the 150 year-old hypothesis of the homology (common evolutionary origin) of the germ layers that form all later organs and tissues.
The Cardiovascular Research Foundation (CRF) today announced the appointment and promotion of Juan F. Granada, MD, as the foundation’s President and Chief Executive Officer. Dr. Granada was also appointed to CRF’s Board of Directors. A renowned leader in cardiology, he joined CRF in 2007 and served as Executive Director and Chief Innovation Officer at the CRF Skirball Center for Innovation.
This is the first nationally representative study in which current use of synthetic cannabinoids is examined. In this study, we found that 3% of high school seniors reported current use, and current users also tend to be current users of other drugs.
The immunotherapy drug nivolumab is safer and more effective than ipilimumab—the current standard of care—in treating patients with resected stage III and stage IV melanoma.
Researchers from the National University of Singapore have established new findings on the properties of two-dimensional molybdenum disulfide (MoS2), a widely studied semiconductor of the future.
People with severe emphysema may breathe better after a minimally invasive procedure that places valves in the airways leading to diseased portions of their lungs, according to a randomized, controlled trial published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
Cancer immunotherapy drugs only work for a minority of patients, but a generic drug now used to increase blood flow may be able to improve those odds, a study by Columbia University Medical Center (CUMC) researchers suggests.
Researchers in Germany have demonstrated that hematopoietic stem cell (HSC) transplants can be improved by treatments that temporarily prevent the stem cells from dying. The approach, which is described in a paper to be published September 7 in The Journal of Experimental Medicine, could allow those in need of such transplants, including leukemia and lymphoma patients, to be treated with fewer donor stem cells while limiting potential adverse side effects.
Lauren Feldman, DMD, clinical assistant professor in the Department of Pediatric Dentistry at the New York University College of Dentistry (NYU Dentistry), has received a five-year, nearly $1 million Primary Care Medicine and Dentistry Clinician Educator Career Development Award from the Health Resources and Services Administration (HRSA). The award will enable Dr. Feldman to develop a formal curriculum that will refine pediatric interprofessional education at NYU Dentistry, the most comprehensive oral healthcare center in the U.S.
Sixteen years after the collapse of the World Trade Center towers sent a “cloud” of toxic debris across Lower Manhattan, children living nearby who likely breathed in the ash and fumes are showing early signs of risk for future heart disease.
Scientists have identified a class of compounds that can block transmission of the parasite that causes malaria and reduce resistance to currently available drugs.
The bending of a hook into wire to fish for the handle of a basket by the crow Betty 15 years ago stunned the scientific world. However, the finding was recently relegated as similar behavioural routines were discovered in the natural repertoire of the same species, suggesting the possibility that Betty’s tool manufacture was less intelligent than previously believed. Now cognitive biologists from the University of Vienna and the University of Veterinary Medicine Vienna studied tool making in an Indonesian cockatoo. Other than the New Caledonian crows Goffin cockatoos are not using tools in the wild. To the researchers' surprise the birds manufactured hook tools out of straight wire (and in a second task unbent curved wire to make a straight tool) without ever having seen or used a hook tool before.
The United States’ National Institutes of Health (NIH) has awarded New York Institute of Technology (NYIT) Professor of Life Sciences Michael Hadjiargyrou, Ph.D., a multi-year grant to study a newly discovered musculoskeletal specific gene, Mustn1, and to determine its role in cartilage regeneration and skeletal repair. Hadjiargyrou’s research will also begin to elucidate a new and as yet uncharacterized protein family important for cartilage and bone biology.
Researchers at the Bluestone Center for Clinical Research at NYU Dentistry have identified a novel molecular mechanism which explains why dark-skinned and light-skinned people respond differently to heat and mechanical stimulation.