Children with even mild or passing bouts of depression, anxiety and/or behavioral issues were more inclined to have serious problems that complicated their ability to lead successful lives as adults, according to research from Duke Medicine.
RTI International - a leading nonprofit research institute - and IBM's Africa research lab have announced a partnership to deploy big data analytics and cognitive technologies to help transform development approaches in Africa and around the world.
North Carolina State University researchers have developed an effective and environmentally benign method to combat bacteria by engineering nanoscale particles that add the antimicrobial potency of silver to a core of lignin, a ubiquitous substance found in all plant cells. The findings introduce ideas for better, greener and safer nanotechnology and could lead to enhanced efficiency of antimicrobial products used in agriculture and personal care.
Adolescents who are exposed to e-cigarette TV advertising are more likely to try e-cigarettes in the future, according to a groundbreaking experiment from researchers at RTI International.
The benefits of exercise are well known, but physical fitness becomes increasingly difficult as people age or develop ailments, creating a downward spiral into poor health. Now researchers at Duke Medicine report there may be a way to improve exercise tolerance and, by extension, its positive effects.
Researchers at the UNC School of Medicine created a first-of-its-kind animal model to pinpoint two biomarkers that are elevated in the most severe form of coronary disease.
An estimated 65 percent of ischemic stroke survivors experience cognitive impairment and decline. However, little is known about the varying roles of cognitive risk and protective factors before, during and after stroke.
A new study showing the negative effects of prolonged high heel use confirms expert consensus on the footwear, according to a UNC Charlotte expert.
Although being overweight with a high body-mass index (BMI) has long been associated with a higher risk for colorectal cancer, thinner patients might not fare as well after treatment for advanced cancer, according to a new study from Duke Medicine.
Caught in the act: Millions of images from citizen scientists show that domestic cats do their hunting close to home in neighborhoods and small urban forests, avoiding areas with coyotes.
In a study published in Nature Medicine, UNC Lineberger Comprehensive Cancer Center researchers report their findings of just how a certain tumor-suppressing protein helps prevent colon cancer. With this discovery, researchers believe they’ve found a possible drug target for colon cancer patients who lack the tumor suppressor.
A panel of experts has developed recommendations for developing patient-focused assessments of health care performance. Their findings were published in the journal Value in Health.
New research identifies the types of investors who are vigilant about corporate fraud, but finds that most of those investors are tracking the wrong red flags – meaning the warning signs they look for are clear only after it’s too late to protect their investment.
Experts have identified new strategies for using electronic health records (EHRs) to treat patients with chronic kidney disease. These recommendations may help clinicians and hospitals better manage individual patients with chronic conditions and identify groups of patients most likely to benefit from different treatment strategies.
University of North Carolina (UNC) School of Medicine researchers have developed an innovative, experimental gene transfer-based treatment for children with giant axonal neuropathy (GAN).
Heart attack patients age 65 and older who have reduced heart function might still benefit from implanted defibrillators, according to a Duke Medicine study published in the Journal of the American Medical Association. But fewer than 1 in 10 eligible patients actually get a defibrillator within a year of their heart attacks, the study found.
In a new pre-clinical study, UNC Lineberger researchers show that they can exploit cancer’s reliance on a particular protein to help fight triple negative breast cancer. They believe the protein could be a potential new drug target.
Researchers at the University of North Carolina and NC State have created the first “smart insulin patch” that can detect increases in blood sugar levels and secrete doses of insulin into the bloodstream whenever needed.
Patients with atrial fibrillation who stopped taking blood thinners before they had elective surgery had no higher risk of developing blood clots and less risk of major bleeding compared to patients who were given a “bridge” therapy, according to research led by Duke Medicine.
A study by The Cancer Genome Atlas network of researchers refined and revealed molecular sub-groups of patients with cutaneous melanoma who could potentially benefit from targeted treatments based on their tumor genetics, and helped clarify the immune system’s role in the disease.
Scientists from the UNC School of Medicine provide the first direct experimental evidence for how primordial proteins developed the ability to accelerate the central chemical reaction necessary to synthesize proteins and thus allow life to arise not long after Earth was created.
Researchers at the Duke Cancer Institute and the Duke Clinical Research Institute have found that younger thyroid cancer patients with lymph node involvement are also at increased risk of dying, contrary to current beliefs and staging prognostic tools that classify young patients as having low-risk disease.
In a study that twists nature’s arm to gain clues into the varied functions of the bacterial genome, North Carolina State University researchers utilize a precision scalpel to excise target genomic regions that are expendable. This strategy can also elucidate gene regions that are essential for bacterial survival.
Wake Forest Baptist Medical Center has received $20 million to study the effects of muscadine grape extract (MGE) on prostate and breast cancers. The gift by a donor who wishes to remain anonymous is the largest ever received by the Medical Center.
At a time when lipid management in the United States is undergoing transition in response to new guideline recommendations and expanding lipid-lowering therapy options, the Duke Clinical Research Institute (DCRI) today announced a new study to better understand contemporary lipid management as well as the beliefs and attitudes of patient and providers regarding cholesterol, cardiovascular risk assessment, and options for lipid treatments.
UNC Charlotte and a major healthcare data company have launched new technology that will help hospitals organize and analyze patient statistics.
A clinical trial of the glucose-control drug sitagliptin among patients with type 2 diabetes and established cardiovascular disease has found it did not raise the risk of major adverse cardiovascular events.
How most babies are protected from acquiring HIV from their infected mothers has been a matter of scientific controversy. Now researchers at Duke Medicine provide new data identifying an antibody response that had long been discounted as inadequate to confer protection.
Scientists at Duke Medicine have produced a 3-D map of the human brain stem at an unprecedented level of detail using MRI technology. In a study to be published June 3 in Human Brain Mapping, the researchers unveil an ultra high-resolution brain stem model that could better guide brain surgeons treating conditions such as tremors and Parkinson’s disease with deep brain stimulation (DBS).
For decades, ultrasound was employed in only a handful of medical specialties. But today it is being used across the spectrum of disciplines, from anesthesiology to urology.
New research shows that the close linkage between the physical properties of amino acids, the genetic code, and protein folding was likely the key factor in the evolution from building blocks to organisms when Earth’s first life was emerging from the primordial soup.
Researchers at Wake Forest Baptist Medical Center report progress in their goal to make use of the more than 2,600 kidneys that are donated each year, but must be discarded due to abnormalities and other factors. The scientists aim to “recycle” these organs to engineer tailor-made replacement kidneys for patients.
A modified poliovirus therapy that is showing promising results for patients with glioblastoma brain tumors works best at a low dosage, according to the research team at Duke’s Preston Robert Tisch Brain Tumor Center where the investigational therapy is being pioneered.
Duke Medicine researchers have found that bladder cells have a highly effective way to combat E. coli bacteria that cause urinary tract infections (UTIs).
For years scientists have been aware of the potential problems of antibiotics being present in wastewater, and the research of engineering professor Olya Keen is showing that treatments to clean wastewater may actually be creating new antibiotics and further contributing to the development of antibiotic resistance in the environment.
Picture yourself in a medical office, anxiously awaiting your annual flu shot. The nurse casually states, “This won’t hurt a bit.” But when the needle pierces your skin it hurts, and it hurts a lot. Your expectations have been violated, and not in a good way.
A national tobacco education campaign, launched by the Centers for Disease Control and Prevention, featuring graphic, testimonial-style advertisements increased intentions to quit smoking, according to a study by RTI International.
New proof-of-concept research suggests the potential for engineering replacement intestine tissue in the lab, a treatment that could be applied to infants born with a short bowel and adults having large pieces of gut removed due to cancer or inflammatory bowel disease.
A head-to-head comparison of two biologic therapies used to treat a subset of patients with advanced kidney cancers provides much-needed clarity on the preferred treatment for the first line of attack.
Smokers who are able to quit might actually be hard-wired for success, according to a study from Duke Medicine. The study, published in Neuropsychopharmacology, showed greater connectivity among certain brain regions in people who successfully quit smoking compared to those who tried and failed.
How can 2015 grads just starting their career journey improve the odds that their first job is the right one — especially this year when employers are hiring, and there may be a second or third offer waiting in the wings?
A nationally recognized program to house Charlotte’s chronically homeless continues to help people and save money as it enters its fourth year, according to a UNC Charlotte report.
Three military veterans will begin earning their master’s degrees at UNC Charlotte aided by substantial awards provided by the University’s Graduate School.
Scientists at the National Institutes of Health have solved a long-standing mystery about the origin of one of the cell types that make up the ovary. The team also discovered how ovarian cells share information during development of an ovarian follicle, which holds the maturing egg.
A University of North Carolina at Chapel Hill analysis published in the journal Tobacco Control synthesized the results of 37 different experiments comparing picture-based and text warnings, finding that picture-based warnings were more effective than text warnings on 20 of 25 different outcome measures.
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