A significant proportion of lung cancer patients also have autoimmune disease, which may make them unsuitable for increasingly popular immunotherapy treatments, a team of researchers at UT Southwestern Medical Center’s Harold C. Simmons Comprehensive Cancer Center has found.
The targeted therapy rucaparib, which has demonstrated robust clinical activity in ovarian cancer patients with a BRCA mutation, also showed promise in previously treated pancreatic cancer patients with the mutation.
While we may think of some people are consistently wise, we actually demonstrate different levels of wisdom from one situation to the next, and factors such as whether we are alone or with friends can affect it, according to new research from the University of Waterloo.
University of Leicester study uses phage-based therapy to address growing challenge of CDI
It's time to say goodbye to ineffective and costly cancer treatments. Japanese scientists have found unique genetic alterations that could indicate whether expensive immune checkpoint inhibitors would be effective for a particular patient.
It has been known for years that personality traits of animals, such as aggressiveness, risk-taking, curiosity or sociality, may have far-reaching consequences for reproduction and survival. However, separating the effect of personality from other factors, such as environmental conditions, is not easy. If the natural environment of the animals is subjected to strong fluctuations, the different personalities may have different consequences depending on the prevailing situation.
Vaccines are usually medicine’s best defense against the world’s deadliest microbes. However, HIV is so mutable that it has so far effectively evaded both the human immune system and scientists’ attempts to make an effective vaccine to protect against it. Now, researchers have figured out how to make a much-improved research tool that they hope will open the door to new and better HIV vaccine designs.
Dartmouth College scientists have discovered that marine microalgae can completely replace the wild fish oil currently used to feed tilapia, the second most farmed fish in the world and the most widely farmed in the United States.
In a preliminary finding (abstract 5568) presented Monday, June 6, at the 2016 American Society of Clinical Oncology Annual Meeting in Chicago, researchers revealed they have found bacteria in the upper female reproductive tract.
Scientists at the University of British Columbia and Vancouver Coastal Health have proven that multiple sclerosis (MS) can be caused by a single genetic mutation – a rare alteration in DNA that makes it very likely a person will develop the more devastating form of the neurological disease.
Bosses play no role in fostering a sense of meaningfulness at work - but they do have the capacity to destroy it and should stay out of the way, new research shows.
In collaboration with Alexion Pharmaceuticals, Inc., scientists from Aarhus University have used X-rays to understand how the therapeutic antibody eculizumab prevents our immune system from destroying red blood cells and damaging kidney tissue.
New research suggests that early severe social deprivation may impact DNA modifications that affect the expression of stress-related genes. These nongenetic (or epigenetic) modifications occur when molecules called methyl groups are added to components of DNA.
Research shows that the human protein, IFITM3, blocks Zika virus replication and prevents cell death.
Working in a more intellectually challenging job is associated with better memory and other aspects of cognitive functioning, reports a study in the June Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine (ACOEM).
Living donors are an increasingly important source of organs for kidney and liver transplantation, giving the world transplant community the responsibility to minimize the benefits to recipients while minimizing the risks to donors. The June issue of Transplantation, the official Journal of The Transplantation Society and the International Liver Transplantation Society, brings brought together the most current data and the best analysts to provide a whole issue devoted to living-donor transplantation. The journal is published by Wolters Kluwer.
Visual blurring—like that produced by bifocals or multifocal lenses—may cause errors in foot position when walking. And that could contribute to the risk of tripping and falling in older adults, suggests a study in the June issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Wolters Kluwer.
Use of Metformin – commonly used as the front-line treatment for type 2 diabetes – improves survival for some breast cancer patients, and shows promise as a treatment for patients diagnosed with endometrial hyperplasia, according to the results of two new studies presented by researchers from the Perelman School of Medicine at the University of Pennsylvania at the American Society of Clinical Oncology (ASCO) Annual Meeting
More precise dosing methods and cellular engineering techniques show promise in the effort to improve treatment of aggressive cancers with personalized cellular therapies, according to new studies from researchers in the Perelman School of Medicine and the Abramson Cancer Center at the University of Pennsylvania and The Children’s Hospital of Philadelphia which will be presented during the 2016 American Society of Clinical Oncology Annual Meeting.
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