New research from Memorial Sloan Kettering Cancer Center (MSK) uses cryo-electron microscopy to shed new light on the ubiquitin; could help predict the risk of blood clots in cancer patients; reveals why micronuclei burst, accelerating aggressive cancers; and surveys healthcare providers about the benefits and risks of commercial genetic testing.
FAU has received a five-year NIH grant to further research on designing and applying statistical methods to identify regions of the genome affected by natural selection, which is an important evolutionary force that enables humans to adapt to new environments and fight disease-causing pathogens.
Advancing the frontiers of agricultural genetics, a newly developed eight-way tomato Multiparental advanced generation intercross (MAGIC) population serves as a rich genetic resource that unlocks diverse traits from wild tomato species.
A new study has mapped the genetic makeup of mango, revealing its genomic diversity and population structure that influence key agronomic traits. The research identifies genetic differentiation among mango populations and discovers candidate genes linked to flowering, fruit weight, and aroma compounds, essential for advancing mango breeding through genomic-assisted methods.
Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.
Scientists have unveiled a revolutionary protospacer adjacent motif (PAM)-less genome editing system using CRISPR-SpRY, marking a major advancement in soybean breeding. This innovative method eliminates the traditional PAM sequence constraints, enabling precise editing at specific loci.
New study reveals how an unexpected genetic mechanism influences the evolution of butterfly wing coloration.
Here, based on her own cancer journey, Joanne Slobodien shares five bits of advice she would give others who are just starting to navigate their diagnosis and treatment plan.
Scientists who have described in a new study the step-by-step details of a bacterial defense strategy see the mechanism as a promising platform for development of a new genome-editing method.
Researchers studied gene expression in plant/mycorrhizae symbioses by analyzing the roots of a model plant colonized by fungi and using a combination of techniques to measure gene activity in individual cells and visualize gene expression within two-dimensional sections of roots.
A cutting-edge study has unveiled the sophisticated methods pathogens use to weaken plant defenses. It shows how a pathogen's effector protein targets the chloroplast protein StFC-II, increasing its levels in chloroplasts and reducing the plant's ability to generate reactive oxygen species (ROS). This manipulation significantly compromises the plant's immune response, offering new insights into potential strategies for enhancing plant resistance to infections.
Every cell in your body holds a unique genetic code within your DNA, inherited from your parents. The segments of your DNA called genes determine nearly all your body’s characteristics and functions.
Andy Groves, PhD, a leading researcher in the development of the inner ear, will head the Department of Developmental Biology at Washington University School of Medicine in St. Louis beginning in April.
A pioneering study has uncovered the genetic basis of dormancy in lychee trees, a tropical evergreen perennial. The research identifies LcSVP2 as a critical gene in the regulation of terminal bud dormancy.
One seeded project will investigate the genetic basis of altered behavior and brain function related to autism spectrum disorder, while the other project aims to explore how collagen dysfunction affects tissue structure and function.
New methods to shape RNA molecules into circles could lead to more effective and long-lasting therapies, shows a study by researchers at the University of California San Diego. The advance holds promise for a range of diseases, offering a more enduring alternative to existing RNA therapies, which often suffer from short-lived effectiveness in the body.
A cutting-edge study has revealed how genetic signals from rootstocks influence drought resistance in grafted walnut trees. Researchers found that by modifying the JrGA20ox1 gene in rootstocks, they could significantly enhance the trees' ability to cope with water scarcity. The study demonstrates a powerful new method for improving agricultural resilience to climate change, offering hope for sustaining walnut production under increasingly challenging environmental conditions.
A pioneering study has revealed the crucial role of cell wall components in tomato fruit ripening. By investigating the effects of altered SlP4H3 gene expression on arabinogalactan proteins (AGPs), researchers have illuminated the complex biochemical processes that control fruit maturation. This discovery could revolutionize agricultural practices, paving the way for tomato varieties with enhanced texture, nutritional value, and resilience to environmental challenges.
A team of researchers at Michigan State University has discovered a set of methods that enabled the first successful CRISPR-based genome editing in Nile grass rats.
Recent research highlights the importance of targeted therapies for treating advanced colorectal cancer (CRC) with rare genetic variants. These mutations, often linked to poor prognosis and limited response to conventional treatments, are being addressed through advanced sequencing technologies and new targeted drugs. This study explores the clinical diagnosis and treatment strategies tailored to these unique genetic profiles.
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