Focus: Hidden - Philly Metro

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In preschool-aged children, a simple test performed in the ophthalmologist's or optometrist's office greatly overestimates the eye's ability to "flex and focus" in order to see small objects clearly, reports a study in the November issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

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Transplantation Direct is a new open access journal being launched as a companion title to Transplantation, the official journal of The Transplantation Society.

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Several lines of research have opened exciting new frontiers in scientific understanding and clinical management of bipolar disorder. Recent advances in bipolar disease research are described in this month's special issue of Harvard Review of Psychiatry. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

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Printed NCCN Guidelines for Patients® available for order on Amazon.com for Breast (Stages 0 – IV), Colon, and Pancreatic Cancers; Malignant Pleural Mesothelioma; Melanoma; Multiple Myeloma; and Soft Tissue Sarcoma.

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Researchers at Drexel University and Dalian University of Technology in China have chemically engineered a new, electrically conductive nanomaterial that is flexible enough to fold, but strong enough to support many times its own weight. They believe it can be used to improve electrical energy storage, water filtration and radiofrequency shielding in technology from portable electronics to coaxial cables.

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Oncology researchers studying gene mutations in the childhood cancer neuroblastoma are refining their diagnostic tools to predict which patients are more likely to respond to drugs called ALK inhibitors that target such mutations. Removing some of the guesswork in diagnosis and treatment may lead to more successful outcomes.

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Villanova History Professor Shares Thoughts Regarding the 25th Anniversary of the Fall of the Berlin Wall

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Olaparib, an experimental twice-daily oral cancer drug, produces an overall tumor response rate of 26 percent in several advanced cancers associated with BRCA1 and BRCA2 mutations, according to new research co-led by the Abramson Cancer Center of the University of Pennsylvania. The positive response provides new hope for patients with ovarian, breast, pancreatic and prostate cancers whose conditions have not responded to standard therapies. Results of the phase II study are available online in the current issue of the Journal of Clinical Oncology.

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A new molecular alteration, consisting in the subcellular delocalization of the well known tumor suppressor protein pRb2/p130, has been recently identified, adding up a new component in the complex molecular portrait that characterizes gastric cancer.

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Insomnia is a "prevalent and persistent" problem for patients in the early phases of recovery from the disease of addiction—and may lead to an increased risk of relapse, according to a report in the November/December Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

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PHILADELPHIA –A diagnosis of septic shock was once a near death sentence. At best, survivors suffered a substantially reduced quality of life. Penn Medicine researchers have now shown that while most patients now survive a hospital stay for septic shock, 23 percent will return to the hospital within 30 days, many with another life-threatening condition -- a rate substantially higher than the normal readmission rate at a large academic medical center. The findings are published in the new issue of Critical Care Medicine.

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The International Anesthesia Research Society (IARS) is pleased to announce that its newest publication, A&A Case Reports, a peer-reviewed online journal that publishes informative clinical experiences, has been accepted for indexing by MEDLINE/PubMed. All articles back to Volume 1 Issue 1 will be loaded to PubMed, as well as all articles published going forward.

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An important addition to the “eat less, move more” strategy for weight loss lies in behavioral counseling to achieve these goals. But research on how primary care practitioners can best provide behavioral weight loss counseling to obese patients in their practices — as encouraged by the Centers for Medicare and Medicaid Services (CMS) — remains slim, according to a systematic review of this topic published today in JAMA. The study was led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

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Two new studies from the Abramson Cancer Center and the Perelman School of Medicine at the University of Pennsylvania offer hope for breast cancer survivors struggling with cancer-related pain and swelling, and point to ways to enhance muscular strength and body image. The studies appear in a first of its kind monograph from the Journal of the National Cancer Institute Monographs focusing on integrative oncology, which combines a variety of therapies, some non-traditional, for maximum benefit to cancer patients.

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According to a new study from researchers at The Children's Hospital of Philadelphia's PolicyLab, the proportion of US-born, Medicaid-enrolled children in Pennsylvania who utilized preventive dental care rose significantly for children ages 5-10 years from 2005-2010, with marked gains among Latino children.

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A new study shows cellular-level changes in nerve structure and function that may contribute to the development of migraine headaches, reports the November issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

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After opening a comprehensive breast center (CBC), one hospital achieved significant improvement in key measures of quality of care for women undergoing breast reconstruction, reports the November issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

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Lippincott Williams & Wilkins, a part of Wolters Kluwer Health, is pleased to announce that Kathleen Murphy White, PhD, RN, NEA-BC, FAAN, has been named Editor-in-Chief of Quality Management in Health Care (QMHC), a leading peer-reviewed journal of evidence, ideas, and experience in improving health care quality and patient outcomes.

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The editors and publisher of Oncology Times, the independent source for hematology/oncology news for the cancer care team, are pleased to announce the appointment of John C. Byrd, MD, as Clinical Advisory Editor. Oncology Times is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

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A new study from The Children’s Hospital of Philadelphia (CHOP) provides valuable evidence that New Jersey’s Graduated Driver Licensing (GDL) decal provision is associated with a sustained two-year decline in crash rates among intermediate or probationary teen drivers.