UT Southwestern Medical Center researchers have identified a compound that selectively eliminates cancer cells while sparing immune cells in a form of cell death known as ferroptosis. The findings, published in Science Translational Medicine, could lead to new treatments for a wide variety of cancer types, the study authors say.
Are you sick and tired of getting sick and tired? A UNLV-led research team is exploring whether the reason we sometimes feel ill in the first place is because our body’s cells suffer from trash that accumulates within them.
Researchers at Umeå University in Sweden, led by Professor Felipe Cava, have identified a new family of enzymes that creates a unique type of cross-linking between the building blocks of bacterial cell walls. This discovery could help develop new antibiotics against infectious diseases.
University of Pittsburgh School of Medicine researchers discovered a molecular mechanism by which excessive dietary protein could increase atherosclerosis risk.
A first-of-its-kind cellular immunotherapy pioneered at Moffitt Cancer Center has received approval from the Food and Drug Administration and is now available for patients with advanced melanoma. Lifileucel is the first tumor-infiltrating lymphocyte therapy, or TIL, approved for solid tumors.
Thanks to advancements in the development of patented synthetic human-like hearts first created at Michigan State, researchers can study human heart development and congenital heart disease on highly accurate models. This is facilitating the development of new therapies and pharmaceutical drugs to treat a variety of heart-related diseases just in time for the observance of American Heart Month in February.
Dr. Nitzan Gonen, a Bar-Ilan University researcher specializing in the process of fetal sex determination, together with research students Aviya Stopel, Cheli Lev and Stav Dahari, has succeeded in creating "laboratory testicles" that may significantly advance understanding of the mechanisms involved in sex determination and provide solutions for male infertility, which affects one in 12 men worldwide.
Neuroscientists from Bonn, New York, and Freiburg discover interactions between so-called "ripples" and nerve cells during human memory processes.
Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have built and demonstrated the potential efficacy of a new chimeric antigen receptor (CAR) T-cell-based immunotherapy specifically designed to treat patients with cutaneous and rare subtypes of melanoma.
Researchers report in the journal Cell that ancient viruses may be to thank for myelin—and, by extension, our large, complex brains.
Com o avanço da idade, as células podem sofrer envelhecimento, um estado no qual elas param de crescer, mas continuam liberando moléculas inflamatórias e tecido degradado.
مدينة روتشستر، ولاية مينيسوتا —مع تقدم السن، يمكن أن تتعرض الخلايا للشَيخُوخَة، وهي حالة تتوقف فيها عن النمو ولكنها تستمر في إطلاق جزيئات التهابية وجزيئات مدمرة للأنسجة. عندما يكون الشخص صغيرًا في السن، يستجيب الجهاز المناعي ويطرح الخلايا الهَرِمة، والتي يشار إليها غالبًا باسم الخلايا الزُومبيّ. ومع ذلك، تبقى خلايا الزُومبيّ باقية وتساهم في العديد من المشاكل والأمراض الصحية المرتبطة بالعمر. سلط الباحثون في مايو كلينك، في دراستين، الضوء على بَيولُوجْيا خلايا الشَيخُوخَة.
Scientists at the UC Davis School of Medicine may have figured out why some people have trouble digesting sorbitol, a sugar alcohol used in sugar-free gum, mints, candy and other products.
A Study by Politecnico di Milano and Istituto Mario Negri has been published in Advanced Materials.
One of the key goals of medical science is to speed up the healing of tissue injuries in a way that would not enable the forming of less functional scar tissue in the affected areas.
Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been uncovered.
Scientists at Cold Spring Harbor Laboratory (CSHL) and the University of California, Davis have reached a new breakthrough in pancreatic cancer research—eight years in the making.
From lab-grown chicken to cricket-derived protein, these innovative alternatives offer hope for a planet struggling with the environmental and ethical impacts of industrial agriculture.
The discovery of a pair of genes that work in perfect harmony to protect male fertility, could provide new insights into some unexplained cases of the most severe form of infertility, research suggests.
Scientists unveil 145 genes vital for genome health, and possible strategies to curb progression of human genomic disorders.
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