Research Alert
Article title: GRK2 promotes activation of lung fibroblast cells and contributes to pathogenesis of pulmonary fibrosis through increasing Smad3 expression
Authors: Yanhui Li, Ying Sun, Nan Wu, Haichun Ma
From the authors: “Inhibition of [G protein-coupled receptor kinase-2] activity may be a potential intervention strategy to treat [idiopathic pulmonary fibrosis] and the effect of paroxetine on preclinical models of pulmonary fibrosis will be determined in future studies.”
This study is highlighted as one of February’s “best of the best” as part of the American Physiological Society's APSselect program.
Journal Link: American Journal of Physiology-Cell Physiology