Even though clinical trials haven’t shown it works against COVID-19, doctors continue to prescribe ivermectin – and a new study suggests health insurers are heavily subsidizing the cost of those prescriptions.
A $7.6 million gift from Judith L. Tam and the Richard Tam Foundation has launched an accelerated research initiative at the University of Michigan Health Rogel Cancer Center to understand why alterations in the ALK gene causes lung cancer to become resistant to standard therapy over time. The goal is to identify biological pathways that can be targeted with new approaches to treatment.
Combining two drugs, intrathecal morphine and oral gabapentin, reduces the amount of postoperative opioid use and side effects for adolescents undergoing a major spinal fusion surgery for scoliosis. Researchers say the method of reducing opioid intake by adding gabapentin has potential to be considered for other procedures beyond spinal fusion for scoliosis.
Preadolescents with severe neuromuscular scoliosis who are treated with growth-friendly surgery prior to spinal fusion have eight times more complications and nine times more unplanned subsequent surgeries than those who only have the spinal fusion, a study suggests. Researchers say the findings will allow parents of young children to make more informed decisions about treatment plans.
Researchers demonstrated that the SWI/SNF complex facilitates access to enhancers that oncogenes can bind to and drive downstream gene expression in cancer. Degrading a subunit of this complex blocks the oncogenes. The finding reveals a novel approach to treating prostate cancers fueled by different genetic drivers, which altogether represent upwards of 90% of all prostate cancers.
Children in a study cohort of young patients requiring ICU care for critical illness had an average of two weeks of school absences; half of primary caregivers missed work during the same period.
Children suffering gunshot wound-related spinal cord injury early less money and receive less education in adulthood than kids with non-violent spinal cord injury, a new study suggests. Greater than two-thirds of the children with gunshot-related injuries earn less than $25,000 annually.
1 in 6 parents rate their stress level as high during the holiday season – with nearly twice as many mothers experiencing high stress than fathers.
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A team of scientists led by the University of Michigan Health Rogel Cancer Center has found that a class of U.S. Food and Drug Administration-approved drugs can effectively stop a highly aggressive type of uterine cancer in its tracks, paving a quick path toward new treatment strategies for a deadly cancer with limited therapeutic options.
The anti-cancer effect of the drug may help those with rare, hereditary cancer syndromes avoid surgeries by shrinking tumors via a daily oral dose.
The Ronald Weiser Center for Prostate Cancer will aim to elevate and optimize the health care experience for patients with prostate cancer and their families by investing in staff, infrastructure, technologies and education as well as research into the disease and its treatment.
A former Division I swimmer, now a physician at University of Michigan Health, will join USA Swimming for international competition in Abu Dhabi on Dec. 16. The competition will feature several Olympic medal-winners.
As major holidays and the promise of a new year approach, a new poll of people over 50 shows that most of them are finding joy and staying resilient amid the pandemic. But a sizable minority are feeling a lot of stress, especially among those who said their overall physical or mental health is fair or poor and those with the lowest incomes.
Nearly a fourth of pregnant and recently pregnant women in a new study say they’ve been unable to afford necessary health care, and three fifths report concern about paying medical bills.
Two complementary studies show that defibrotide can successfully suppress the formation and progression of neutrophil extracellular traps, or NETs, which are web-like networks of toxic proteins that play a role in forming blood clots and promoting inflammation in several disease, including COVID-19. Researchers say findings may set the stage for defibrotide clinical trials in potentially several diseases.
When it comes to learning how to prevent heart disease, including diverse populations isn’t just the right thing to do, it also makes the science better.
Maternal morbidity risks may continue well into the late postpartum period, especially for individuals who are Black or have depression or anxiety, new research suggests.
Racial and ethnic diversity in biobanks and genetic databases is crucial for the accuracy of artificial intelligence (AI) and biomarker research and products. But a new study shows how bias can creep in.
As the need for youth violence prevention escalates, two studies show that "SafERteens," an evidence-based behavioral intervention designed to engage youth at this high-risk time and reduce violence involvement, can be successfully integrated as a part of routine medical care delivery in both emergency and primary care settings. Researchers say it has the potential for critical impact on long-term violence outcomes for youth.
The University of Michigan Health Rogel Cancer Center has earned a three-year accreditation from the National Accreditation Program for Rectal Cancer, a quality program of the American College of Surgeons’ Commission on Cancer.
Tips and resources for parents of children in the wake of the Michigan school shooting and amid the stress of the pandemic
A Michigan Medicine study found that only 7.4% of patients treated for an opioid overdose at U.S. emergency departments are prescribed naloxone, an overdose rescue drug often available under the name Narcan, within 30 days. The prescription rate for buprenorphine, a medication to treat opioid addiction, was just 8.5%. Researchers say clinicians are missing critical opportunities to save lives in the ER and during follow-up visits.
Michigan Medicine ranked number third for high-quality scientific research publications in 2020, according to The Nature Index rankings. Compiled by Nature Research, the rankings provide an overview of research for institutions and countries based on the number of scientific articles published in 82 high-quality natural-science journals.
Trips, slips and falls are a major cause of injury, hospitalization and death in older people, and the pandemic may have increased their risk. Prevention can start with quick fixes in their homes that can be made during a holiday visit.
As families prepare to celebrate a holiday focused on gratitude, many parents say their children aren’t as thankful as they should be.
A new study from the University of Michigan Health Rogel Cancer Center finds circulating tumor DNA, or ctDNA, levels can predict as early as two weeks after starting treatment which patients are likely to have good outcomes. At the same time, specialized MRI and PET scans two weeks after starting chemoradiation also correlated with outcomes.
Nearly one in three older adults plans a long trip far from home in the next year, and many look forward to holiday travel in the next two months, a new poll finds. But many said they would consider local COVID-19 case rates at their destination.
A recent study found that advanced kidney disease is associated with death for cerebral palsy patients independent of related factors, such as cancer and cardiovascular conditions.
A 13-year effort to track the mental health of new doctors in their most stressful time of training shows signs that things have gotten better. But those first-year residents, also called interns, still have a sizable risk of developing depression. And many who do still don’t seek help.
Even though most COVID-19 cases come from exposure to airborne coronavirus, a new study points to the importance of surfaces as a reservoir of risk in nursing homes -- especially certain objects close to the beds of patients who have COVID-19.
Female physicians who are parents made more changes and experienced greater depression and anxiety during the pandemic than male physician-parents. Data from before the pandemic shows a gender gap in new-onset depression.
Most mental health care in America doesn’t happen in psychiatrists’ offices – especially when it comes to children, teens and young adults. It happens in primary care settings. As needs spike due to the pandemic, a program offers a psychiatry "lifeline" for Michigan's primary care providers, and online education for providers anywhere.
Stretch marks cause pregnant women and individuals substantial embarrassment that can negatively impact pregnancy and quality of life, a new study found. The lesions, and concerns for developing and permanency, may be contributing factors for depression or anxiety in the perinatal period, which affect up to one in seven women during pregnancy and postpartum. Researchers say this should bring new focus on stretch marks and identifying mental health disorders during pregnancy and the postpartum period.
The more parents engaged in conversation with preschoolers during shared TV time, the more likely those children were to have higher curiosity levels when they reached kindergarten, a new study suggests.
It’s common for people with psoriasis to develop dry, inflamed skin lesions. But researchers found specific gene expression changes in healthy-appearing skin were a better predictor of clinical response to etanercept, an anti-TNF treatment prescribed to up to one-fifth of psoriasis patients. They say finding predictive signs in a patient’s genetic profile is a step toward applying precision medicine to complex inflammatory skin diseases.
Tips and insights from a 5-gallon donor, aimed at people who have never given blood and those who stopped a while ago. A critical shortage of blood could jeopardize care for people with cancer, organ failure, traumatic injury and more.
With two viruses threatening to make older adults sick this winter, a new poll shows most people over 50 have gotten protected by vaccines against both influenza and coronavirus, or plan to. And a majority of those who have gotten the COVID-19 vaccine plan to get an additional dose. But the poll also reveals major differences in vaccine attitudes between older adults, including those of different political leanings.
Research uncovers racial bias in oxygen readings during the COVID-19 pandemic, even amongst patients needing ECMO.
Patients with a rare form of scleroderma that causes more skin thickening have a greater chance of dying from related heart, lung and kidney problems, a new study found. This occurs despite the patient population taking drugs used to treat most people with scleroderma. Researchers say it is an opportunity for more targeted drug development.
Registrations for the national organ transplant waiting list related to alcoholic hepatitis as well as the number of deceased donor liver transplants for the inflammatory liver condition rose significantly during the pandemic, Michigan Medicine researchers found.
A new report finds women physicians across all races and ethnicities earn less than their male counterparts. This new data reinforces that academic medicine must find a better approach to how they pay physicians. The authors of a NEJM perspective lay out some potential solutions.
Even as the opioid epidemic dominated national attention over the past decade, the rate of overdose deaths involving cocaine, methamphetamine and other stimulants tripled, a new study in veterans suggests.
Depression and anxiety in pregnant women may be connected to the type of delivery they have, new research suggests.
Researchers at the University of Michigan Health Rogel Cancer Center have identified a drug that, when given along with a bone marrow transplant, drops the risk of leukemia recurring by 20% among the high-risk patients.
Americans who get seriously ill from COVID-19 in 2021 might have to pay thousands of dollars in bills from their hospitals, doctors and ambulance companies, a new study suggests. Most health insurance companies voluntarily waived co-pays, deductibles and other cost-sharing for hospitalized COVID-19 patients in 2020, but many major insurers lifted those waivers in early 2021.
Interviews with two dozen emergency medicine residents in academic medical center found most placed importance on learning to deliver high-quality care to diverse populations. However, many did not feel their programs made enough effort to incorporate effective cultural competency education into the curriculum.
Parents in a new national poll report that half of children aged 10-12 years and a third of children ages 7-9 use their devices to engage with others on social media apps.
Genetic meta-analysis helps researchers detect genes related to FMD, a cardiovascular disease that affects mostly women, and defines relationships to other more common cardiovascular conditions.
About one in six doctor’s office visits by older Americans no longer takes place in an actual doctor’s office, but rather online or over the phone, a new analysis of telehealth visits billed to Medicare in the past two years finds.
An international research team has found a small-molecule inhibitor that was able to suppress tumor growth in animal models of a childhood glioma — offering new hope toward developing therapies.
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