A neurologic pathway by which non-damaging but high frequency brain impact blunts normal brain function and causes long-term problems with learning and memory has been identified. The finding suggests that tailored drug therapy can be designed and developed to reactivate and normalize cognitive function, say neuroscientists at Georgetown University Medical Center.
In a new report commissioned by the Global Preparedness Monitoring Board (GPMB), Georgetown global health experts say the success of any effort to redress pandemic preparedness failures demonstrated by COVID-19 requires a re-centering of governance that would include greater accountability, transparency, equity, participation and the rule of law.
Individuals who can unconsciously predict complex patterns, an ability called implicit pattern learning, are likely to hold stronger beliefs that there is a god who creates patterns of events in the universe, according to neuroscientists at Georgetown University.
Infants and young children have brains with a superpower, of sorts, say Georgetown University Medical Center neuroscientists. Whereas adults process most discrete neural tasks in specific areas in one or the other of their brain’s two hemispheres, youngsters use both the right and left hemispheres to do the same task. The finding suggests a possible reason why children appear to recover from neural injury much easier than adults.
Misconceptions about the way climate and weather impact exposure and transmission of SARS-CoV-2, the virus that causes COVID-19, create false confidence and have adversely shaped risk perceptions, say a team of Georgetown University researchers.
An online COVID-19 symptom tracking tool developed by researchers at Georgetown University Medical Center ensures a person’s confidentiality while being able to actively monitor their symptoms. The tool is not proprietary and can be used by entities that are not able to develop their own tracking systems.
A brain imaging study of veterans with Gulf War illness (GWI) and patients with chronic fatigue syndrome (CFS) (sometimes called myalgic encephalomyelitis), has shown that the two illnesses produce distinctly different, abnormal patterns of brain activity after moderate exercise. The result of the Georgetown University Medical Center study suggests that GWI and CFS are distinct illnesses, an outcome that could affect the treatment of veterans with Gulf War illness.
Education appears to protect older adults, especially women, against memory loss, according to a study by investigators at Georgetown University Medical Center, published in the journal Aging, Neuropsychology, and Cognition.
Approximately three quarters of the deaths associated with COVID-19 in the nation’s capital have been among the African American community. A new Georgetown University report illuminates entrenched health and socioeconomic disparities that explain one reason this is occurring. Main points: • 15-year difference in the life expectancy between residents in Ward 3 and Ward 8; • Residents from Wards with more Black residents (5, 7, and 8) more likely hospitalized for preventable health conditions; • Number of Blacks who are obese is 3x higher than Whites; • Number of Blacks with diabetes is 7x higher than Whites; • Number of Blacks who die from heart disease is 2.5 times higher than Whites; • Median household income is 3x less for Blacks; and • Blacks have the lowest percentage of bachelor degree attainment.
A Georgetown University Medical Center clinical trial investigating the cancer drug nilotinib in people with Alzheimer’s disease finds that it is safe and well-tolerated, and researchers say the drug should be tested in a larger study to further determine its safety and efficacy as a potential disease-modifying strategy.
Global health scholars have issued a clarion call about the needless loss of life expected because of a foreseeable prospect of “slow and inadequate access to supplies” to control COVID-19 in sub-Saharan Africa. They say what is unfolding now is similar to when lifesaving diagnostics and treatments came to the region long after they were available elsewhere.
As governments from countries including the U.S., Germany, Italy and the U.K., explore the possibility of issuing so-called “immunity passports,” a leading global health and legal scholar warns that such action poses significant practical, equitable, and legal issues. In contrast, if and when a vaccine is developed, vaccination certificates will likely play an important role in ending the pandemic and protecting global health.
Misuse of prescription benzodiazepines (such as alprazolam or Xanax, and diazepam or Valium) has been linked to nicotine use. Evidence of how nicotine “sets up” a craving for benzodiazepines — often called “benzos” — in animal laboratory studies has been published in the open access journal eNeuro.
An online survey of nearly 500 veterans with Gulf War illness (GWI) suggests a high burden of disease almost three decades after the conflict.
A bacteria typically linked to periodontal disease, Fusobacterium nucleatum (F. nuc), could play an important role in the rising incidence of colorectal cancer in people under the age of 45. Another type of bacteria, Moraxella osloensis, has been found in colorectal cancer tumors at a nearly four-fold higher rate in people over 75 than in those under 45 years of age, pointing out how differences in the bacteria that comprise what is known as the body’s microbiome could affect cancer outcomes to varying degrees. These are the preliminary findings of an ongoing study that will be presented at the American Society of Clinical Oncology Gastrointestinal Cancers Symposium in San Francisco from January 23-25, 2020.
Mice given a new drug targeting a key gene involved in lipid and glucose metabolism could tolerate a high-fat diet regimen (composed of 60% fat from lard) without developing significant liver damage, becoming obese, or disrupting their body’s glucose balance.
Adding a medication used to treat epilepsy, bipolar disorder and migraines to a blood pressure medicine reversed some aspects of breast cancer in the offspring of mice at high risk of the disease because of the high fat diet fed to their mothers during pregnancy. Conversely, this treatment combination increased breast cancer development in the offspring whose mothers had not been fed a high fat diet during pregnancy.
A clinical trial investigating the repurposed cancer drug nilotinib in people with Parkinson’s disease finds that it is reasonably safe and well tolerated. Researchers also report finding an increase in dopamine, the chemical lost as a result of neuronal destruction, and a decrease in neurotoxic proteins in the brain among study participants. Finally, they say nilotinib, a tyrosine kinase inhibitor, potentially halts motor and non-motor decline.
Brain imaging of veterans with Gulf War illness show varying abnormalities after moderate exercise that can be categorized into two distinct groups — an outcome that suggests a more complex illness that previously thought.
When FDA approved palbociclib (Ibrance ®), there was very little data about the safety of this drug in people with benign ethnic neutropenia (BEN), which is common in women of color. Some of these women didn’t qualify for the clinical trials because of the required blood count, which is lower in women with BEN.
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