A new study demonstrates that an approach that combines behavioral science with social media and online communities can lead to increased AIDS testing and improved health behaviors among men at risk of HIV infection. The approach is also applicable across a variety of diseases.
UCLA researchers have described a new form of irritable bowel syndrome (IBS) that occurs after an acute bout of diverticulitis, a finding that may help lead to better management of symptoms and relief for patients.
A study from UCLA’s Jonsson Comprehensive Cancer Center has found that head and neck cancer patients receiving radiation as part of their treatment were less likely to suffer unwanted side effects such as worsening of diet, need for a feeding tube, or narrowing of the throat passage if they complied with a set of prescribed swallowing exercises called a swallow preservation protocol during therapy.
Four prominent researchers from UCLA’s Eli & Edythe Broad Center of Regenerative Medicine and Stem Cell Research have received Early Translational research awards totaling approximately $13 million from the California Institute for Regenerative Medicine (CIRM) the state stem cell agency.
A team of scientists from the UCLA Departments of Surgery and Pathology and Laboratory Medicine have been awarded a three-year, $2 million grant from the W.M. Keck Foundation to fund research aimed at increasing the quality of donor livers.
Dr. Hanna Mikkola, member of the UCLA Eli & Edythe Broad Center for Regenerative Medicine & Stem Cell Research and the Jonsson Comprehensive Center and an associate professor of molecular, cell, and developmental biology in the life sciences received the 2013 McCulloch and Till Award from the Society for Hematology and Stem Cells (ISEH).The annual award recognizes junior scientists in experimental hematology and stem cells.
A new study points to a simple solution to the high cost of medications that could result in hundreds of dollars in savings per patient: Instead of brand-name drugs, substitute less expensive counterparts that have a similar therapeutic effect .
A culturally tailored HIV prevention program developed and tested by investigators at UCLA and the Charles R. Drew University of Medicine and Science has been shown to significantly reduce unprotected sex among bisexual black men.
A clinical trial conducted at the Children's Discovery and Innovation Institute at Mattel Children's Hospital UCLA has found that, compared with soybean oil, a limited duration (24 weeks) of fish oil is safe and effective in reversing liver disease in children with intestinal failure who require intravenous nutrition. The researchers believe that fish oil may also decrease the need for liver and/or intestinal transplants — and mortality — associated with this disease.
UCLA researchers have discovered that creating a personal website to chronicle the cancer experience and communicate with the author’s interpersonal circle can reduce depressive symptoms, increase positive mood, and enhance appreciation for life in women diagnosed with breast cancer.
Before the digital age, neuroscientists got their information in the library like the rest of us. But the field’s explosion has created nearly 2 million papers -- more data than any researcher can read and absorb in a lifetime.
A collaborative team of researchers including scientists from UCLA has uncovered evidence that a specific genetic alteration appears to contribute to schizophrenia. They also found that schizophrenia shares a common biological pathway with Fragile X mental retardation syndrome.
Researchers at UCLA’s Jonsson Comprehensive Cancer Center have successfully combined cellular therapy and gene therapy in a mouse model system to develop a viable treatment strategy for breast cancer that has metastasized to the patient’s brain.
UCLA’s Jonsson Comprehensive Cancer Center and the David Geffen School of Medicine department of urology have received renewal notification from the National Cancer Institute as a Specialized Program of Research Excellence (SPORE) site in prostate cancer, marking the beginning of a third cycle of funding aimed at improving prevention, detection and treatment of a disease that will kill 30,000 American men this year.
A good state of mind — that is, your happiness — affects your genes, say scientists from UCLA's Cousins Center for Psychoneuroimmunology and the University of North Carolina. They examined how positive psychology impacts human gene expression and found that different types of happiness have surprisingly different effects on the human genome.
UCLA researchers have measured how the brain behaves in so-called hypersexual people who have problems regulating their viewing of sexual images. The study found that the brain response of these individuals to sexual images was not related in any way to the severity of their hypersexuality but was instead tied only to their level of sexual desire.
The United States is one of 86 countries whose constitutions do not guarantee their citizens any kind of health protection. That's the finding of a new study from the UCLA Fielding School of Public Health that examined the level and scope of constitutional protection of specific rights to public health and medical care, as well as the broad right to health.
A research team that examined the relationship between religious practices and obesity among Indian immigrants has found that religiosity in Hindus and Sikhs — but not Muslims — appears to be an independent factor associated with being overweight or obese.
UCLA’s Jonsson Comprehensive Cancer Center is ranked among the top 12 cancer centers in the nation, according to a U.S. News & World Report survey of board-certified physicians from across the country. The survey reviewed patient outcomes, the cancer center’s reputation among physicians, mortality rates and other care-related factors.
The UCLA Health System's hospitals in Westwood and Santa Monica have been named to U.S. News and World Report's most exclusive rankings list: the Best Hospitals 2013–14 Honor Roll. UCLA was ranked No. 5 in the country and No. 1 in both California and the Los Angeles metropolitan area. The annual U.S. News Best Hospitals rankings, now in their 24th year, recognize hospitals that excel at treating the most challenging patients. This year's Honor Roll highlights just 18 hospitals out of nearly 5,000 nationwide for their rare breadth and depth of clinical excellence.
Researchers from UCLA’s Jonsson Comprehensive Cancer Center have discovered that specific types of bacteria that live in the gut are major contributors to lymphoma, a cancer of the white blood cells that are part of the human immune system.
A study on HIV-positive women who were sexually abused as children has found that the more severe their past trauma, the greater their improvement in an intervention program designed to ease their psychological suffering.
The UCLA Health System has been named a "Leader in LGBT Healthcare Equality" in the Healthcare Equality Index, an annual survey conducted by the Human Rights Campaign Foundation, the educational arm of the country's largest lesbian, gay, bisexual and transgender (LGBT) organization.
The health system earned top marks for its commitment to equitable, inclusive care for LGBT patients and their families, who can face significant challenges in securing adequate health care. UCLA applied for the distinction to demonstrate its commitment to the goals of human rights, education, outreach and a better understanding of LGBT individuals in the community and within its health system.
UCLA researchers have found that a workshop for adolescents that teaches skills to keep impulsive acts under control, is effective. Such impulsive behavior often leads to negative acts including substance abuse and violence.
For the first time, the UCLA Health System and its hospitals have been designated among the nation's "most wired" institutions in recognition of their implementation and use of information technology in their health-care delivery systems. The annual Health Care's Most Wired Survey, sponsored by Hospitals and Health Networks magazine, measures a hospital's level of adoption of information technology (IT) relative to other hospitals and health systems. The survey data is distributed, collected and analyzed by Health Forum, an American Hospital Association company, which develops industry-standard benchmarks for IT adoption.
UCLA researchers have found a possible biological explanation for narcolepsy. In addition, they have shown for the first time that the numbers of new neurons in the brain can increase greatly and not just serve as replacement cells. This may underlie recovery and learning and open new routes to treatment of a number of neurological disorders.
UCLA pediatric neurosurgeon Dr. Gary Mathern was recently honored with the Ambassador for Epilepsy Award by the International Bureau for Epilepsy and the International League Against Epilepsy.
Brain aneurysms of all sizes—even small ones no larger than a pea—are up to 12 times more likely to rupture if they are growing, according to a new UCLA study. The discovery counters current guidelines and emphasizes the need for regular monitoring and earlier treatment.
A new study examined the content of doctor–patient conversations about dietary supplements and found that, overall, physicians are not particularly good at conveying important information concerning them to their patients.
UCLA Researchers have successfully established the foundation for using hematopoietic (blood-producing) stem cells from the bone marrow of patients with sickle cell disease to treat the disease.
New research reveals that the likely culprit behind Alzheimer's has a different molecular structure than current drugs' target -- perhaps explaining why current medications produce little improvement in patients.
Study suggests that care for older patients with chronic geriatric conditions such as dementia and depression was significantly improved when co-managed by both a primary care physician and a nurse practitioner, highlighting the crucial role these nurses can play in treating these conditions.
UCLA researchers have found that older adults who regularly used a brain-fitness program on a computer demonstrated significantly improved memory and language skills.
A team led by UCLA researchers has conducted a major study on the importance of the speed of treatment when using a clot-busting drug, and found that treatment time has a profound influence on outcome.
A UCLA team of surgeons and gastroenterologists has been performing a new, minimally invasive procedure to remove large and hard-to-reach polyps while keeping the colon intact. The procedure, which combines two minimally invasive techniques, has currently been performed at only a handful of medical centers in the United States.
UCLA's Dr. Gary Mathern has been appointed co-editor-in-chief of Epilepsia, the official journal of the International League Against Epilepsy (ILAE) and the leading source for current clinical and research results on all aspects of epilepsy.
Hyundai Hope on Wheels and Los Angeles-area Hyundai dealers have awarded a $75,000 Hyundai Scholar Grant to Dr. Vivian Chang, a clinical instructor in pediatric hematology and oncology and co-director of the Pediatric Cancer Predisposition Clinic at Mattel Children’s Hospital UCLA, for her work researching DNA sequencing technology to identify cancerous genes.
Progesterone, a female hormone that can be used as a therapy for endometrial cancer, eliminates tumor cells indirectly by binding to its receptor in stromal or connective tissue cells residing in the tumor microenvironment, according to a study from the G.O. Discovery Lab team and collaborators at UCLA.
Women with a severe form of morning sickness who take antihistamines to help them sleep through their debilitating nausea are significantly more likely to experience adverse pregnancy outcomes, including low birth weight babies and premature births, a UCLA study has found.
Researchers from the UCLA Department of Obstetrics and Gynecology have isolated a new population of primitive, stress-resistant human pluripotent stem cells easily derived from fat tissue that are able to differentiate into virtually every cell type in the human body without genetic modification.
Researchers at UCLA’s Jonsson Comprehensive Cancer Center have found that the burden of bladder cancer on the population is very high, and that more intense surveillance and treatment in the first two years after diagnosis could reduce the number of patients whose cancer returns after treatment and lower the death rate from this disease.
UCLA researchers find abnormal brain networks in Fragile X syndrome, a genetic malady that is the most common inherited cause of autism and intellectual disability.
Researchers from UCLA’s Jonsson Comprehensive Cancer Center report preliminary results showing significant antitumor activity with very manageable side effects from a new drug being tested in patients with advanced melanoma, the deadliest form of skin cancer.
Testicular orphan nuclear receptor 4 (TR4) is overexpressed in pituitary tumors that spark the excess production of adrenocorticotrophic hormone (ACTH). The scientists discovered that by knocking down TR4 in lab mice, they were able to reverse tumor growth and excess ACTH production.
Research has shown that healthy behaviors are associated with a lower risk of Alzheimer's disease and dementia, but less is known about the potential link between positive lifestyle choices and milder memory complaints, especially those that occur earlier in life and could be the first indicators of later problems.
UCLA researchers now have the first evidence that bacteria ingested in food can affect brain function in humans. In an early proof-of-concept study of healthy women, they found that women who regularly consumed beneficial bacteria known as probiotics through yogurt showed altered brain function, both while in a resting state and in response to an emotion-recognition task.
The Patient-Centered Outcomes Research Institute (PCORI) has approved a $1.6 million research award to the Children's Discovery and Innovation Institute at Mattel Children's Hospital UCLA to study the use of videoconferencing technology to deliver behavioral health services to pediatric patients in community primary care settings.
UCLA researchers examining outcomes for advanced heart-failure patients over the past two decades have found that, coinciding with the increased availability and use of new therapies, overall mortality has decreased and sudden cardiac death, caused by the rapid onset of severe abnormal heart rhythms, has declined. However, the team found that even today, with these significant improvements, one-third of patients don’t survive more than three years after being diagnosed with advanced disease.