Latest News from: Joslin Diabetes Center

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Article ID: 714245

Genetic marker linked to increased risk of diabetic peripheral neuropathy

Joslin Diabetes Center

BOSTON – (June 11, 2019) – Researchers from Joslin Diabetes Center, using a genome-wide association study, have identified a genetic factor linked to the development of diabetic peripheral neuropathy. This finding suggests a new target for preventive therapies. The research has been published online and will appear in the August print issue of Diabetes.

Released:
11-Jun-2019 2:05 PM EDT

Article ID: 713942

Researchers Restore Beta-Cell Function by Deleting Old Cells

Joslin Diabetes Center

Research from Joslin Diabetes Center has shown in mice that insulin resistance increases the proportion of aged beta-cells which are dysfunction. Such an increase in aged beta-cells could lead to type 2 diabetes. These researchers confirmed similarly increased proportion of aged beta-cells in islets recovered from humans with type2 diabetes.

Released:
4-Jun-2019 4:05 PM EDT
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Article ID: 713185

Study identifies enzymes that prevent diabetic kidney disease

Joslin Diabetes Center

BOSTON -- (May 13, 2019) -- A new study from Joslin Diabetes Center has proven that certain biological protective factors play a large role in preventing diabetic kidney disease in certain people. The study was published today in Diabetes Care. This study built on the findings from a 2017 Joslin Medalist Study of protective factors and diabetic kidney disease (or DKD).

Released:
20-May-2019 1:05 PM EDT
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Article ID: 712410

Pushing early beta-cell proliferation can halt autoimmune attack in type 1 diabetes model

Joslin Diabetes Center

Researchers at Joslin have found that increasing the proliferation and turnover of beta cells before signs of type 1 diabetes could halt the development of the disease.

Released:
6-May-2019 11:05 AM EDT
Newswise: Study sheds light on strategies for managing diabetic macular edema in people with good vision

Article ID: 712234

Study sheds light on strategies for managing diabetic macular edema in people with good vision

Joslin Diabetes Center

BOSTON – (April 29, 2019) – Newly available results will influence the standard approach for treating diabetic macular edema in patients with good vision, thanks to a study published today in the Journal of the American Medical Association. The study was conducted by the DRCR Retina Network, a multicenter clinical research network funded by the National Eye Institute, part of the National Institutes of Health (NIH).

Released:
1-May-2019 3:05 PM EDT
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Article ID: 711723

Researchers identify new novel circulating proteins that are involved in progression of diabetic kidney disease to end stage renal failure

Joslin Diabetes Center

BOSTON – (April 22, 2019) -- In a breakthrough study published today in Nature Medicine, researchers at Joslin Diabetes Center have identified a group of 17 circulating inflammatory proteins that are consistently associated with the development and progression of diabetic kidney disease. These 17 proteins, called the Kidney Risk Inflammatory Signature (KRIS), could allow doctors to determine the risk of progression to end stage renal disease in a patient with diabetic kidney disease.

Released:
22-Apr-2019 3:05 PM EDT
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Article ID: 711091

Breast Milk Analyses Could Lead to New Opportunities for Reducing Earliest Risk of Childhood Obesity

Joslin Diabetes Center

BOSTON – (April 10, 2019) -- New research suggests the composition of breast milk in normal weight mothers differs from that of overweight mothers, and that variations in small molecule metabolites found in breast milk are possible risk factors for childhood obesity. The new research is published online in The American Journal of Clinical Nutrition.

Released:
10-Apr-2019 12:05 PM EDT
Newswise: New Evidence Links Lifespan Extension to Metabolic Regulation of Immune System
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    21-Mar-2019 11:00 AM EDT

Article ID: 709747

New Evidence Links Lifespan Extension to Metabolic Regulation of Immune System

Joslin Diabetes Center

Researchers at Joslin Diabetes Center have uncovered a new mechanism of lifespan extension that links caloric restriction with immune system regulation.

Released:
18-Mar-2019 12:05 PM EDT
Newswise: Insulin Signaling Failures in the Brain Linked to Alzheimer’s Disease

Article ID: 707912

Insulin Signaling Failures in the Brain Linked to Alzheimer’s Disease

Joslin Diabetes Center

Scientists continue to find evidence linking Type 2 diabetes with Alzheimer’s disease, the most common form of dementia and the seventh leading cause of death in the United States. However, little is understood about the mechanism by which the two are connected.Now, researchers at Joslin Diabetes Center, an affiliate of Harvard Medical School, have demonstrated that impaired insulin signaling in the brain negatively affects cognition, mood and metabolism, all components of Alzheimer’s Disease.

Released:
13-Mar-2019 12:20 PM EDT
Newswise: SGLT-2 inhibitors induce a fasting state that triggers metabolic benefits
  • Embargo expired:
    7-Mar-2019 9:00 AM EST

Article ID: 709210

SGLT-2 inhibitors induce a fasting state that triggers metabolic benefits

Joslin Diabetes Center

Joslin researchers detail how SGLT-2 inhibitors induce a fasting state in the body without requiring the patient to sharply cut back on food intake. This triggers a host of beneficial metabolic effects.

Released:
6-Mar-2019 12:05 PM EST

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