Latest News from: Michigan Medicine - University of Michigan

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Newswise: Researchers develop first inhibitors against key epigenetic complex involved in cancer
Released: 21-Jun-2021 11:05 AM EDT
Researchers develop first inhibitors against key epigenetic complex involved in cancer
Michigan Medicine - University of Michigan

Activity of the polycomb repressive complex 1 is essential for the development and maintenance of leukemic cells; disrupting it presents a new potential therapeutic approach.

Newswise: BET Inhibitors Show Promise in Overcoming Lineage Plasticity, A Newly Recognized Form of Resistance to Prostate Cancer Drugs
Released: 18-Jun-2021 11:45 AM EDT
BET Inhibitors Show Promise in Overcoming Lineage Plasticity, A Newly Recognized Form of Resistance to Prostate Cancer Drugs
Michigan Medicine - University of Michigan

In a new study, a team of researchers uncovered new mechanisms underlying an important type of resistance to modern prostate cancer drugs called lineage plasticity, where castration-resistant prostate cancers undergo a deadly identity switch. They also outline a promising path to overcoming this form of resistance: BET bromodomain inhibitors.

Released: 18-Jun-2021 8:00 AM EDT
Personalized Medicine, Not X-rays, Should Guide Common Forearm Fracture Treatments in Older Adults
Michigan Medicine - University of Michigan

A decade-long study of distal radius fracture in older adults revealed that personalized medicine catering to a patient’s individual needs and environment, not age or X-rays, should guide treatment options. The federally funded study is the most collaborative, intense effort to try and answer a 200-year puzzle about how to treat one of the most common fractures in older adults.

Released: 18-Jun-2021 7:05 AM EDT
Teamwork saves lives: COVID-19 hospital network shares key findings to improve care
Michigan Medicine - University of Michigan

Data sharing among 40 Michigan hospitals about the care and outcomes for thousands of inpatients with COVID-19 has led to reduced variation and findings that could inform care anywhere, including approaches for preventing blood clots and reducing overuse of antibiotics, as well as a risk prediction tool.

Released: 18-Jun-2021 7:05 AM EDT
One-third of older Americans delayed health care over COVID concerns
Michigan Medicine - University of Michigan

Nearly one in three Americans between the ages of 50 and 80 put off an in-person appointment for medical care in 2020 because they were worried about exposure to the novel coronavirus, new national poll data show.

14-Jun-2021 9:00 AM EDT
1 in 6 families in new study spent more than $5,000 to have a baby
Michigan Medicine - University of Michigan

When delivering moms require caesarians or their newborns need neonatal care, some families may spend as much as $10,000 out-of-pocket, according to a new Michigan Medicine-led study.

Released: 16-Jun-2021 10:50 AM EDT
Online Mental Health Intervention Significantly Helps the Isolated, Immunosuppressed During Pandemic
Michigan Medicine - University of Michigan

People with the rare autoimmune disease scleroderma, who likely experience more serious isolation during a global pandemic, saw their anxiety and depression improve after receiving online mental health intervention through an international study. Researchers say the support program could be extended to many vulnerable patient populations moving forward.

Released: 10-Jun-2021 12:00 PM EDT
Study Shows When People with Cerebral Palsy Are Most Likely to Break Bones
Michigan Medicine - University of Michigan

Researchers at Michigan Medicine found people with cerebral palsy have fragile bones that present high fracture risk, but at different times across the lifespan compared to the general population. The results helped them develop new sex-specific critical periods of bone health for this population.

Released: 10-Jun-2021 10:35 AM EDT
Many surgery patients get opioid prescriptions, but many don’t need to, study suggests
Michigan Medicine - University of Michigan

Surgeons can ease their patients’ pain from common operations without prescribing opioids, and avoid the possibility of starting someone on a path to long-term use, a pair of new studies suggests.

Released: 9-Jun-2021 3:10 PM EDT
Smokers needed angioplasty and stenting a decade before non-smokers
Michigan Medicine - University of Michigan

Smokers needed their blocked arteries fixed nearly a decade earlier than non-smokers, and patients with obesity underwent these procedures four years earlier than non-obese patients, according to a new study from across Michigan.

Newswise: Poll finds risky drinking patterns in older adults during pandemic
7-Jun-2021 11:20 AM EDT
Poll finds risky drinking patterns in older adults during pandemic
Michigan Medicine - University of Michigan

As many older adults get back to normal life across the United States thanks to high rates of vaccination and lower COVID-19 activity, a new poll suggests many should watch their alcohol intake.

Released: 8-Jun-2021 2:30 PM EDT
Harnessing healthy behaviors to prevent dementia
Michigan Medicine - University of Michigan

The approval of a new Alzheimer's disease drug is getting a lot of attention, but a recent scientific review of the evidence about dementia prevention shows an important role for primary care providers and patients to modify risk factors and protect brain health over the long term.

Newswise: Analysis reveals how kidney cancer develops and responds to treatment
3-Jun-2021 12:45 PM EDT
Analysis reveals how kidney cancer develops and responds to treatment
Michigan Medicine - University of Michigan

By sequencing the RNA of individual cells within multiple benign and cancerous kidney tumors, researchers from the University of Michigan Rogel Cancer Center have identified the cells from which different subtypes originate, the pathways involved and how the tumor microenvironment impacts cancer development and response to treatment.

Released: 7-Jun-2021 11:55 AM EDT
New Potential Therapy for Fatty Liver Disease
Michigan Medicine - University of Michigan

In a subset of patients with partial lipodystrophy and/or NASH, the hormone leptin can be leveraged as a therapeutic agent to move fat out of the liver.

Released: 4-Jun-2021 12:05 PM EDT
Dollars to donuts: What will it take to get more of the U.S. vaccinated against COVID-19?
Michigan Medicine - University of Michigan

Prizes, lotteries, discounts and freebies for COVID-19 vaccination may help overcome vaccine hesitancy and reward the vaccinated too, but it's important to learn from this moment to inform other preventive health care, an expert says.

Released: 4-Jun-2021 10:55 AM EDT
Statewide quality improvement project reduced excessive radiation treatments for bone metastases by 80%
Michigan Medicine - University of Michigan

An effort by the Michigan Radiation Oncology Quality Consortium reduced unnecessary radiation therapy procedures, and saved the time and resources of patients and families.

Released: 3-Jun-2021 11:30 AM EDT
Researchers Predict COVID Baby Boom
Michigan Medicine - University of Michigan

The COVID-19 shutdown initially seemed to hit pause on pregnancy and birth rates, new research from one major hospital system suggests, but that trend is quickly reversing.

Released: 2-Jun-2021 7:05 AM EDT
Patients hospitalized for COVID-19 in 2021 could pay thousands of dollars, study suggests
Michigan Medicine - University of Michigan

Americans who get seriously ill from COVID-19 in 2021 might have to pay thousands of dollars in bills from their hospitals, doctors and ambulance companies as insurance companies allow waivers for out-of-pocket costs to expire, a new study suggests.

Released: 28-May-2021 2:05 PM EDT
Older Adults with Cerebral Palsy Need More, Receive Less Physical Therapy for Painful Conditions
Michigan Medicine - University of Michigan

Older adults with cerebral palsy are more likely to experience debilitating pains of musculoskeletal conditions, but researchers found they receive significantly less physical therapy for those ailments. The lead author says the results, while staggering, support their hypothesis that people with CP receive inequitable health care.

Released: 28-May-2021 10:00 AM EDT
Cholesterol-carrying protein found to help suppress immune response in pancreatic tumor microenvironment
Michigan Medicine - University of Michigan

The protein ApoE has known roles in cardiovascular disease and Alzheimer’s — new research implicates it in pancreatic cancer.

Released: 25-May-2021 4:10 PM EDT
Physician-patient gender concordance may not matter in interventional practice
Michigan Medicine - University of Michigan

While some studies suggest female patients treated by female physicians have better outcomes, there does not appear to be a relationship between operator and patient gender and outcome in patients undergoing coronary angioplasty or stenting.

Released: 25-May-2021 11:40 AM EDT
Nearly Half of COVID-19 Patients Left Hospital in Worse Physical Condition
Michigan Medicine - University of Michigan

Much of the conversation around COVID-19 focuses on death and survival. But 45% of patients hospitalized for the virus at Michigan Medicine during the pandemic's first wave experienced significant functional decline. Nearly 20% were discharged to a location other than their home. Researchers say this information highlights the true impact of COVID-19.

21-May-2021 9:50 AM EDT
Babies with Seizures May Be Overmedicated
Michigan Medicine - University of Michigan

Continuing antiseizure treatment after a baby's neonatal seizures stop may not be necessary.

20-May-2021 1:50 PM EDT
Vast under-treatment of diabetes seen in global study
Michigan Medicine - University of Michigan

Nearly half a billion people have diabetes, but only 1 in 10 of those in low- and middle-income countries are getting the kind of care that could make their lives healthier, longer and more productive, according to a new global study of data. Many don’t even know they have the condition.

Released: 21-May-2021 9:55 AM EDT
A treatment barrier falls, but more remain, for people with opioid issues
Michigan Medicine - University of Michigan

Now that a key policy regarding prescription of a medication for opioid use disorder has been changed, experts reflect on the remaining challenges standing in the way of more people getting effective medication-assisted treatment, and discuss efforts to overcome those barriers.

19-May-2021 4:35 PM EDT
Nearly 3% of Americans take immune-weakening drugs that may limit COVID vaccine response
Michigan Medicine - University of Michigan

A study of more than 3 million insured U.S. adult patients under 65 found that nearly 3% take immunosuppressive drugs that may elevate risk for severe COVID-19 symptoms and hospitalization if they became infected. There is growing evidence that immunosuppressive drugs may also reduce the COVID vaccine's efficacy.

Released: 18-May-2021 2:15 PM EDT
Bone Marrow Disorder Nearly 10-Times More Common in Those with Venom Allergy
Michigan Medicine - University of Michigan

In the largest U.S. study of venom allergy and mastocytosis prevalence, Michigan Medicine researchers found that people with venom allergy are nearly 10 times more likely to suffer the bone marrow disorder that causes higher risk of fatal reactions. They also found that elevated levels of tryptase, a chemical secreted by allergy cells, may predict if a person is at higher risk for reaction to immunotherapy.

Released: 17-May-2021 11:15 AM EDT
Researchers Discover First Immune Stimulating Long Noncoding RNA Involved in Body's Response to Cancer
Michigan Medicine - University of Michigan

U-M researchers have discovered the first immune stimulating long noncoding RNA Involved in the body's response to cancer, suggesting potential approaches to improve immunotherapy treatment.

Newswise: Routine Testing Before Surgery Remains Common Despite Low Value
17-May-2021 10:40 AM EDT
Routine Testing Before Surgery Remains Common Despite Low Value
Michigan Medicine - University of Michigan

Before undergoing surgery, patients often go through a number of tests. In fact, about half of patients who had one of three common surgical procedures done in Michigan between 2015 and the midway point of 2019 received at least one routine test beforehand.

Released: 17-May-2021 8:55 AM EDT
Confused About the Latest Mask Rules? Read This
Michigan Medicine - University of Michigan

A quick guide to navigating life now that the CDC and many states have said that fully vaccinated people do not need to wear masks in many situations.

Newswise: More Kids Seeing Doctors Virtually but Some Parents Still Hesitant
11-May-2021 1:20 PM EDT
More Kids Seeing Doctors Virtually but Some Parents Still Hesitant
Michigan Medicine - University of Michigan

While some parents still have reservations about using telemedicine for their kids, the majority were satisfied with the experience, a new national poll suggests.

Released: 14-May-2021 11:00 AM EDT
No Excuses: Stop Procrastinating on These Key Health Checks
Michigan Medicine - University of Michigan

A quick guide to the most-valuable preventive care that adults need to get scheduled, to catch up on what they may have missed during the height of the pandemic, and to address issues that the pandemic might have worsened.

Newswise: Researchers Develop First-in-Class Inhibitors Against Key Leukemia Protein
Released: 14-May-2021 8:05 AM EDT
Researchers Develop First-in-Class Inhibitors Against Key Leukemia Protein
Michigan Medicine - University of Michigan

Researchers have developed first-in-class small-molecule inhibitors against a key leukemia protein, ASH1L.

Newswise: Gout Treatment Success Doubled by Combining Two Drugs, Study Finds
Released: 11-May-2021 9:00 AM EDT
Gout Treatment Success Doubled by Combining Two Drugs, Study Finds
Michigan Medicine - University of Michigan

If left untreated, gout can cause severe disability. But unlike rheumatoid arthritis, there are only a handful of ways to treat it. Researchers say a combination of two existing drugs disrupts antibody production and doubles treatment efficacy.

Released: 10-May-2021 9:30 AM EDT
Patient support programs for painful conditions may reduce opioid use
Michigan Medicine - University of Michigan

Programs that provide ongoing support to patients with painful conditions and complex medication regimens may also help them avoid using potentially risky opioid pain medications, or reduce the amount they use, a new study finds.

Released: 10-May-2021 9:25 AM EDT
Even small bills for health insurance may cause healthy low-income people to drop coverage
Michigan Medicine - University of Michigan

Twenty dollars a month might not seem like a lot to pay for health insurance. But for people getting by on $15,000 a year, it’s enough to make some drop their coverage – especially if they’re healthy. That could keep them from getting preventive or timely care, and could leave their insurance company with a sicker pool of patients than before.

Newswise: Pandemic worsened many older adults’ mental health and sleep, poll finds, but long-term resilience also seen
28-Apr-2021 10:35 AM EDT
Pandemic worsened many older adults’ mental health and sleep, poll finds, but long-term resilience also seen
Michigan Medicine - University of Michigan

Nearly one in five older adults say their mental health has gotten worse since the pandemic began in March 2020, and an equal percentage say their sleep has suffered in that time too. More than 1 in 4 say they’re more anxious or worried than before the COVID-19 era, according to a new poll of people age 50 to 80.

Newswise: Care Teams Differ for Black, White Surgical Patients in the Same Hospitals
29-Apr-2021 2:45 PM EDT
Care Teams Differ for Black, White Surgical Patients in the Same Hospitals
Michigan Medicine - University of Michigan

A new study finds Black patients are more likely to die after their heart bypass surgery if they’re at a hospital where some care teams see mostly white patients and others see mostly Black patients. On the other hand, mortality rates are comparable between Black and white patients after heart bypass surgery when the teams of health care providers at their hospitals all care for patients of all races.

28-Apr-2021 10:55 AM EDT
Treating dental pain with opioids linked to higher risk of overdose in patients and family members
Michigan Medicine - University of Michigan

When they go to the dentist, patients might not think that the pain prescription they receive could put them or their family at risk of an opioid overdose. But a new study shows that overdose rates were two and a half times higher among patients who filled a prescription for an opioid medication after a dental procedure.

Newswise:Video Embedded few-young-adult-men-have-gotten-the-hpv-vaccine
VIDEO
27-Apr-2021 10:35 AM EDT
Few young adult men have gotten the HPV vaccine
Michigan Medicine - University of Michigan

Just 16% of men 18 to 21 years old have received at least one dose of the HPV vaccine at any age. Yet oropharyngeal cancer, which occurs in the throat, tonsils, and back of the tongue, is now the leading cancer caused by HPV — and 80% of those diagnosed with it are men.

Released: 26-Apr-2021 12:35 PM EDT
Who Has a Right to Ask if You’re Vaccinated?
Michigan Medicine - University of Michigan

COVID-19 vaccination has become a lightning rod for controversy over “vaccine passports” and claims of violations of medical privacy or individual rights. But as two experts explain, there's a long history of efforts to protect the health of others by requiring individuals to provide proof of vaccination or of a past infection, or seek a medical or religious exception.

Released: 23-Apr-2021 8:45 AM EDT
New data could inform youth-focused pandemic messaging
Michigan Medicine - University of Michigan

Newly published analyses of data from polls of teens and young adults show the importance of framing pandemic-related messaging in terms of their role in protecting others from COVID-19.

Newswise: Delaying cardiovascular surgeries due to COVID-19 has serious psychological effects on patients, study finds
Released: 19-Apr-2021 2:05 PM EDT
Delaying cardiovascular surgeries due to COVID-19 has serious psychological effects on patients, study finds
Michigan Medicine - University of Michigan

Postponing procedures during the pandemic sparked anxiety and fear among patients, with many concerned about dying of their conditions before getting surgery.

Released: 19-Apr-2021 11:40 AM EDT
Attacking Aortic Aneurysms Before They Grow
Michigan Medicine - University of Michigan

New basic science research shows what happens to the development of abdominal aortic aneurysms when you inhibit JMJD3 through both genetics and pharmacology.

Released: 19-Apr-2021 11:35 AM EDT
Two Blood Thinners at Once: More Risk with the Same Reward
Michigan Medicine - University of Michigan

For some patients, adding aspirin to a direct oral anticoagulant is an equation that rarely adds up.

Released: 19-Apr-2021 11:00 AM EDT
New Urine-based Test Holds Promise for Detecting Aggressive Prostate Cancer
Michigan Medicine - University of Michigan

A new, urine-based test for aggressive prostate cancer being developed at the University of Michigan uses next-generation sequencing to assess 15 biomarkers to find cancer that can be missed by biopsies or imaging tests.

Newswise: Latest COVID Wave Fills Beds, Hammers Michigan ER Workers
Released: 15-Apr-2021 11:30 AM EDT
Latest COVID Wave Fills Beds, Hammers Michigan ER Workers
Michigan Medicine - University of Michigan

Michigan Medicine's adult and pediatric emergency rooms are experiencing a surge in positive COVID cases and hospitalizations. Younger patients are being admitted and Michigan is seeing a spread of the B.1.1.7 variant. Physicians are again asking the public for help to save lives and keep the ICUs from hitting capacity.

Released: 15-Apr-2021 8:05 AM EDT
Epidemic of firearm injury spurs new wave of research
Michigan Medicine - University of Michigan

Now that federal funding is flowing again for research on firearm injury prevention, some of the few already-funded researchers doing work in this area react and look ahead.


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