UCLA researchers have identified a compound that can reproduce the effect of exercise in muscle cells in mice. The findings are published today in the journal Cell Reports Medicine.
UCLA scientists discovered that astrocytes, a cell type long implicated in brain diseases, is remarkably malleable and shows responses in a mouse model that suggest potential targets for drugs for Huntington’s disease.
Dr. Antoni Ribas, a world-renowned physician–scientist and professor of medicine at the David Geffen School of Medicine at UCLA, has been named to the National Academy of Medicine, one of the highest honors in the fields of health and medicine.
Dr. Erin Chamberlain, a medical oncologist with the UCLA Health San Luis Obispo office, helps decipher common breast cancer terms.
UCLA researchers have found that a drug that activates the body’s natural defenses by behaving like a virus may also make certain stealthy melanoma tumors visible to the immune system, allowing them to be better targeted by immunotherapy.
A review of 39 randomized clinical trials by scientists from UCLA and their colleagues from other institutions has found that combining the use medication with psychoeducational therapy is more effective at preventing a recurrence of illness in people with bipolar disorder than medication alone.
UCLA scientists and colleagues studying the effects of cognitive behavioral therapy (CBT) discovered an abnormality in the brains of people with obsessive compulsive disorder (OCD) that may also help to predict who is most likely to respond to CBT.
How kindergarten teachers helped UCLA researchers highlight the impact of socioeconomic barriers on children’s health and development.
The U.S. Food and Drug Administration has granted emergency use authorization for UCLA Health to launch a new method of COVID-19 detection using sequencing technology called SwabSeq. Capable of testing thousands of samples at once, the method returns accurate, individual results in 12 to 24 hours.
A new report suggests that lingering “brain fog” and other neurological symptoms after COVID -19 recovery may be due to post-traumatic stress disorder (PTSD), an effect observed in past human coronavirus outbreaks such as SARS and MERS.
A coalition of 11 academic institutions and their community partners across California has received a $4.1 million grant from the NIH for a statewide community-engaged approach to addressing COVID-19 among populations that have been disproportionately affected by the pandemic.
Antibiotics may be a good choice for some, but not all, patients with appendicitis, according to results from the Comparing Outcomes of Drugs and Appendectomy (CODA) trial.
UCLA researchers have received a $13 million grant from the National Institutes of Health to find new ways to overcome melanoma resistance to some of the most promising targeted therapies and immunotherapies.
The percentage of low- and middle-income families with children that had burdensome out-of-pocket health care costs fell following the 2014 implementation of the health insurance marketplaces and Medicaid expansion provisions of the Affordable Care Act, known widely as Obamacare,
Dr. Keith Vossel, who is known for his discovery that many Alzheimer’s patients experience nighttime seizures that disrupt their sleep, is the new director of the Mary S. Easton Center for Alzheimer’s Disease Research at UCLA.
UCLA researchers and their colleagues from two other institutions have been awarded a $52 million grant from the National Institutes of Health to lead an international study to better understand the cause and effect of schizophrenia in high-risk youth.
To help better understand the impact and outcomes of COVID-19 in people undergoing cancer treatment, UCLA are participating in a NCI study with cancer centers across the country.
UCLA researchers shed light on how interferon-gamma (IFN-y) guides the treatment response in people with advanced melanoma who are treated with one of the leading immunotherapies — immune checkpoint blockade.
UCLA researchers and colleagues who analyzed electronic health records found that there was a significant increase in patients with coughs and acute respiratory failure at UCLA Health hospitals and clinics beginning in late December 2019, suggesting that COVID-19 may have been circulating in the area months before the first definitive cases in the U.S. were identified. This sudden spike in patients with these symptoms, which continued through February 2020, represents an unexpected 50% increase in such cases when compared with the same time period in each of the previous five years.
A new UCLA study shows partially overlapping patterns of brain function in people with anorexia nervosa and those with body dysmorphic disorder, a related psychiatric condition characterized by misperception that particular physical characteristics are defective.
To better understand the effect of the COVID-19 pandemic on cannabis and CBD use, the UCLA Cannabis Research Initiative has launched the Cannabis, CBD and COVID Survey.
Study finds that older adults with depression are showing resilience during the COVID-19 pandemic.
The Simms/Mann-UCLA Center for Integrative Oncology has received a $50,000 grant from Los Angeles-based PHASE ONE Foundation to support psychosocial care for people with cancer, their families and frontline healthcare workers during the COVID-19 pandemic.
A test designed by UCLA researchers can pinpoint which people with gonorrhea will respond successfully to the inexpensive oral antibiotic ciprofloxacin, which had previously been sidelined over concerns the bacterium that causes the infection was becoming resistant to it.
UCLA researchers have found that chemotherapy is not commonly used when treating adults with localized sarcoma, a rare type of cancer of the soft tissues or bone. In a nationwide analysis of nearly 20,000 patients whose cancer had not yet spread to other organs, the scientists learned that only 22% were treated with some form of chemotherapy.
UCLA has launched a major new study, sponsored by and in collaboration with Apple, designed to help revolutionize detection and treatment of depression.
The AIDS Clinical Trials Group (ACTG) has initiated the ACTIV-2 Outpatient Monoclonal Antibodies and Other Therapies Trial. ACTIV-2 includes both phase 2 and phase 3 evaluations of multiple promising investigational agents for treating early COVID-19 in a single trial.
UCAL researchers are developing a nanotechnology-enabled cancer diagnostic solution that will help detect early stage liver cancer for people who are at risk of developing the disease.
Although discomfort, confusion and even political affiliation are often cited as reasons that make people less likely to wear a mask in public, the psychological traits that shape a person’s behavioral choices may also factor into the decision.
A team of UCLA neurologists have uncovered new potential drug targets in the brains of patients with Alzheimer’s disease, after testing more than a thousand patient samples
Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified the process by which stem cells in the airways of the lungs switch between two distinct phases — creating more of themselves and producing mature airway cells — to regenerate lung tissue after an injury.
In a new study looking at adoptive cell transfer products bearing a transgenic T-cell receptor (TCR), researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a discordant phenomenon in which a subset of patients displayed profoundly decreased expression of the transgenic TCR over time, despite the transgenic TCR being present at the DNA level.
A study by UCLA researchers shows that in people with mild cases of COVID-19, antibodies against SARS-CoV-2 — the virus that causes the disease — drop sharply over the first three months after infection, decreasing by roughly half every 36 days on average. If sustained at that rate, the antibodies would disappear within about a year.
Researchers at the UCLA Jonsson Comprehensive Cancer Center and UCLA School of Dentistry have identified a potential new combination therapy to treat advanced head and neck squamous cell carcinoma, the most common type of head and neck cancer.
A UCLA-led study has found that dermatopathologists, who specialize in diagnosing skin diseases at the microscopic level, are motivated both by patient safety concerns and by malpractice fears — often simultaneously — when ordering multiple tests and obtaining second opinions, with a higher proportion of these doctors reporting patient safety as a concern. When ordering additional microscopic tests for patients, 90% of the dermatopathologists surveyed cited patient safety as a concern and 71% of them reported malpractice fears. Similarly, when obtaining second reviews from a consulting pathologist or recommending additional surgical sampling, 91% cited safety concerns and 78% malpractice concerns.
Annabelle de St. Maurice, MD, MPH, co-chief infection prevention officer for UCLA Health, speaks on The Centers for Disease Control and Prevention's guide for youth sports to resume.
In response to the COVID-19 pandemic, UCLA Mattel Children’s Hospital launched an innovative project to support the emotional needs of children through a new AI powered robot. Robin’s technology enables the robot to build what is called associative memory — it recognizes a child’s emotions by interpreting his or her facial expressions and builds responsive dialogue by replicating patterns formed from previous experiences.
New UCLA research conducted in mice could explain why some people suffer more extensive scarring than others after a heart attack. The study, published in the journal Cell, reveals that a protein known as type 5 collagen plays a critical role in regulating the size of scar tissue in the heart.
Scientists discovered that histones act as an enzyme that converts copper into a form that can be used by the cells. The finding refutes earlier theories that copper spontaneously converts in the body into a usable state.
A UCLA-led study has found that in 2 of 3 states and jurisdictions with policies that require students entering school to receive the human papillomavirus vaccine, vaccination rates among 13-to-17-year-olds were significantly higher than in surrounding states without such policies.
As California prepares for a potential surge of COVID-19, there is a pressing need to determine how critical care resources should be allocated, especially if there is an extreme shortage of those resources.
Youth who are Black, Indigenous and people of color (BIPOC) that also identify as LGBTQ+ representation of sexual orientations and gender identities experience higher rates of social discrimination and isolation, including bullying, family rejection and a lack of social support. Here are ways that family and friends can support them.
States with the highest level of income inequality had a larger number of COVID-19-related deaths compared with states with lower income inequality. New York state, with the highest income inequality, had a mortality rate of 51.7 deaths per 100,000 vs. Utah, the state with the lowest income inequality and which had a mortality of 0.41 per 100,000.
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