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On Monday, October 15, UC San Diego Health will open a new comprehensive health center located at 16950 Via Tazon in Rancho Bernardo. Described as a “clinic of the future,” the new 57,000 square foot facility will offer patients increased access to a team of top doctors and nurses, and an array of convenient services, such as urgent care and advanced imaging, including a pharmacy and optical boutique.

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Researchers at University of California San Diego School of Medicine, with collaborators across the country, report that people who participate in dementia prevention trials are primarily motivated by altruism and pleased to help.

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Starting in the fall of 2018, UC San Diego Health will be the first health system in San Diego County to implement a policy ensuring that all mandatory reporters are responsible for reporting cases of suspected human trafficking. This policy will be a coordinated effort of administrative and professional staff at all points of entry into the health system.

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Human milk oligosaccharides (HMOs) are complex carbohydrates that are highly abundant and unique to human milk. Accumulating evidence indicates that exposure to HMOs in the postnatal period has both immediate and long-term benefits to infant health and development. Researchers at University of California San Diego School of Medicine report for the first time that HMOs are also present in amniotic fluid.

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The National Institute on Aging has awarded scientists at University of California San Diego School of Medicine and San Diego State University with a five-year, $4 million grant to boost the number of Latino and other underrepresented minority researchers studying Alzheimer’s disease and related dementias afflicting seniors of Latino origins, a demographic historically overlooked.

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In the wake of media and public reports about increased mortality linked to a new drug for treating Parkinson’s disease psychosis, researchers at University of California San Diego School of Medicine conducted a retrospective study of qualifying patients in the UC San Diego Health system concluding that the new drug, pimavanserin (marketed as Nuplazid), did not pose a statistically significant greater risk of death.

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In a study publishing September 26 in Science Advances, researchers at University of California San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences report that tweaking factors in a cystic fibrosis lung model, such as pH balance and oxygen, helped eradicate pathogenic bacteria while minimizing risks of antibiotic resistance and overgrowth of other microorganisms.

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Access to world class care is now easier, faster and at the fingertips of UC San Diego Health patients and loved ones. With the new MyUCSDHealth mobile application, patients have the ability to manage their health information and communicate with their physicians while family members and friends can find helpful resources, such as visiting hours, directions and parking information.

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More than 100 UC San Diego Health physicians have been named as “Top Docs” in the 2018 San Diego Magazine “Physicians of Exceptional Excellence” survey, an annual opportunity for doctors across the region to vote for much-admired colleagues.

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Using a bioinformatics approach, University of California San Diego School of Medicine researchers found that CD4+ T cell’s binding partner, a molecule called MHC-II, may have even more influence on emerging tumors than MHC-I, the better known partner of CD8+ T cells. The finding, published September 20 in Cell, may help researchers improve cancer immunotherapies and predict which patients will respond best.

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Researchers at University of California San Diego School of Medicine have unraveled new insights into the way cells leverage G-protein-coupled receptors (GPCRs) and their cellular waste disposal systems to control inflammation. The findings, published September 18 in Cell Reports, suggest some existing cancer drugs that inhibit these cellular activities might be repurposed to treat vascular inflammation, which occurs when artery-blocking plaques form in atherosclerosis.

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Researchers at University of California School of Medicine are preparing to launch a novel clinical trial to examine the safety, efficacy and pharmacological properties of cannabis as a potential treatment for adults with essential tremor (ET). Currently, ET is treated using repurposed medications originally developed for high blood pressure or seizures.

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On Saturday, October 6, hundreds of hackers are expected to descend upon the University of California San Diego campus to put their collaborative problem-solving capabilities to the test.

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Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego have now identified three new molecular drug targets in Naegleria fowleri and a number of drugs that are able to inhibit the amoeba’s growth in a laboratory dish. Several of these drugs are already approved by the U.S. Food and Drug Administration for other uses, such as antifungal agents, the breast cancer drug tamoxifen and antidepressant Prozac.

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Researchers at University of California San Diego School of Medicine have discovered using mice and human clinical specimens, that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis (NASH), a chronic and aggressive liver condition. By identifying caspase-2’s critical role, they believe an inhibitor of this enzyme could provide an effective way to stop the pathogenic progression that leads to NASH — and possibly even reverse early symptoms.

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Researchers at the University of California San Diego say they have dramatically advanced the science of biometric identification, creating a novel technology that can capture the fingerprints of infants and children, even on the first day of birth.

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Two to three million years ago, the functional loss of a single gene triggered a series of changes in what would eventually become the modern human species. Researchers at University of California San Diego School of Medicine report on studies of mice engineered to lack the same gene and resulting data that suggest the lost gene may also have contributed to humanity’s well-documented claim to be among the best long-distance runners in the animal kingdom.

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Macrophages are immune cells that are supposed to protect the body from infection by viruses and bacteria. Yet Zika virus preferentially infects these cells. Researchers at University of California San Diego School of Medicine have now unraveled how the virus shuts down the genes that make macrophages function as immune cells.