He has also become co-leader of the Neurobiology and Brain Tumor Program within the St. Jude Comprehensive Cancer Center. These combined units comprise one of the largest clinical brain tumor programs in North America.
Scientists at St. Jude Children’s Research Hospital determined structures of a transporter protein involved in the movement of neurochemicals such as serotonin and dopamine, unearthing multiple mechanisms that can guide drug development.
St. Jude Children’s Research Hospital and ALSAC, its fundraising and awareness organization, announced new leaders of the St. Jude Board of Governors and ALSAC Board of Directors today. The announcement comes at a time when St. Jude is advancing the largest strategic investment in its 61-year history.
In 2019, St. Jude lentiviral gene therapy restored the immune system in multiple infants of X-linked severe combined immunodeficiency disorder (SCID-X1) or “bubble boy disease” at the DNA level. These children can now produce functional immune systems.
Scientists at St. Jude Children’s Research Hospital unraveled the genetics increasing the chance of survivors developing a second cancer later in life and its severity and prognosis to guide future cancer prevention.
St. Jude researchers shed light on a key player in cancer development by exploring the ability of fusion oncoproteins to form condensates in cells.
The new patient family housing building was made possible by a multi-million dollar donation from the pizza giant.
Scientists at St. Jude Children’s Research Hospital may be able to better predict outcomes and treat patients with the most common childhood cancer by more clearly defining hyperdiploidy.
Scientists at St. Jude Children’s Research Hospital found that a subset of CD8+ T cells in the brain lessens the activation of microglia and limits disease pathology in a model of Alzheimer’s disease.
Scientists at St. Jude Research Hospital unravel the mechanisms behind a key culprit in chemotherapy resistance.
St. Jude Children’s Research Hospital scientists found that immune cells present in individuals long before influenza infection predict whether the illness is symptomatic.
Award-winning NICU expert spent 21 years at Children’s Wisconsin, including four years as executive director of perinatal and neonatal services.
Scientists at St. Jude Children’s Research Hospital showed that fixed mutations within a viral population most likely stem from how easy it is to acquire that mutation (i.e., mutation accessibility) rather than just its benefit.
Former Chair of Computational Biology honored with induction into Class of 2023 Fellows.
Scientists at St. Jude Children’s Research Hospital used genomics to inform the creation of genetic and new cell-line models for hepatoblastoma, which pointed toward the DNA damage repair pathway as a promising therapeutic route.
Scientists at St. Jude Children’s Research Hospital and colleagues in Latin America found that early identification of clinical deterioration saves lives, especially in hospitals with the greatest need.
Scientists at St. Jude Children’s Research Hospital found that altering amounts of the nutrient glutamine in the tumor microenvironment could enhance or impair the immune system’s anti-cancer response.
Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease and beta thalassemia. Scientists at St. Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard found base editing increased fetal hemoglobin production in a new treatment.
Scientists at St. Jude Children’s Research Hospital found key “on” switch, NLRP12, for innate immune cell death in diseases that cause red blood cells to rupture, which can lead to inflammation and multi-organ failure.
Scientists at St. Jude Children’s Research Hospital have discovered H5N1 avian influenza viruses gained the ability to cause severe disease and target the brain in mammals as they spread across North America.
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