Research Alert

Maternal Antibiotic Treatment May Harm Preemies’ Lungs

Changes in gut microbiome, oxygen treatment lead to inflammation, reduced immunity in mouse study


Newswise — Article title: Perinatal maternal antibiotic exposure augments lung injury in offspring in experimental bronchopulmonary dysplasia

Authors: Kent A. Willis, David T. Siefker, Michael M. Aziz, Catrina T. White, Naiha Mussarat, Charles K. Gomes, Amandeep Bajwa, Joseph F. Pierre, Stephania A Cormier, Ajay J. Talati

From the authors: “Our study provides valuable experimental evidence that manipulation of the gut microbiota by antibiotic exposure influences the progression of lung injury.”

This study is highlighted as one of December's "best of the best" as part of the American Physiological Society's APSselect program.

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