Research Alert

Article title: CDC-derived extracellular vesicles reprogram inflammatory macrophages to an arginase 1-dependent pro-angiogenic phenotype

Authors: Kyle I. Mentkowski, Asma Mursleen, Jonathan D. Snitzer, Lindsey M. Euscher, Jennifer K. Lang

From the authors: “Our study was designed to gain mechanistic insight into the role of [CDC-derived extracellular vesicles] in modulating macrophage phenotypes and operant signaling pathways to better understand their potential contribution to immunomodulatory cardioprotection.”

This study is highlighted as one of June’s "best of the best" as part of the American Physiological Society's APSselect program.

Journal Link: American Journal of Physiology- Heart and Circulatory Physiology