Using Nitric Oxide in Medicinal Strategies Optimizes Replacing, Engineering or Regenerating Human Cells

17-May-2019 2:40 PM EDT

Nathan Bryan, Ph.D.

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Newswise — ORLANDO . . . May 18, 2019 . . .More than one million stem cell treatments have been conducted in the United States during the past ten years. Physicians and other healthcare providers are beginning to realize regenerative medicine is the future of medicine; however major health issues remain unanswered. Dr. Nathan Bryan, one the country’s leading experts in the mechanism of nitric oxide, will tell more than seven thousand physicians attending the 27th Annual Spring Conference of the American Academy of Anti-Aging Medicine on Saturday that “the ability to use our own cells to heal our own body make good medical sense.

“However, sick people have sick and dysfunctional cells.  Therefore, even with the enormous success rate of stem cell treatments, putting sick and dysfunctional cells back into sick people has never made sense to me.  My research has focused on how we make the stem cells and the stem cell environment better prior to the harvesting and deployment of stem cells. The ‘smart’ use of nitric oxide makes a huge difference in health outcomes.” 

Dr. Bryan is an Adjunct Assistant Professor at Baylor College of Medicine in the Department of Molecular and Human Genetics and has authored or edited 6 books on nitric oxide.

His lecture described the role of nitric oxide in normal stem cell function and underscore how normal stem cell function is lost with age and disease.  His research and lecture focused on three main topics.

  1. The effects of nitric oxide on stem cell function and activity
  2. What goes wrong in people that cannot make nitric oxide and the effect this has on healing
  3. How do physicians improve the production of nitric oxide and improve cellular function so that stem cell therapy can be enhanced, and outcomes improved in patients?

Bryan said, “Regenerative medicine is a powerful new tool to improve health. However, the body must be ready to accept the stem cell therapy. After all, it only makes sense to improve the function of the stem cells and deliver functional cells to sick people rather than delivering sick cells to sick people. This is the vital role nitric oxide plays. It helps the body heal and improve cell function so there is a greater chance the stem cell therapy will be successful.  Nitric oxide is a signaling molecule that tells stem cells where to go and what to do.  Without adequate nitric oxide production, stem cells administered to patients are confused as they do not know where to go or what to become.  In fact, the bioavailability of nitric oxide may predict stem cell treatment success or failure. 

“The challenge is great because most people do not have adequate amounts of nitric oxide in their body now. Importantly, as we age the body slows the natural production of nitric oxide. Moderate exercise and eating foods that can be metabolized into nitric oxide or taking supplements proven in clinical trials to restore nitric oxide production are important steps everyone should take.  Not only will stem cell administered work better but our body’s ability to mobilize our own stem cells will work better” he said.

Bryan is credited with a multitude of significant discoveries in Nitric Oxide function, production and metabolism, and has published extensively in peer-reviewed scientific journals in the field. He’s an inventor who has been awarded more than a dozen US and International patents related to his discoveries on Nitric Oxide.

The (A4M) is dedicated to the advancement of healthcare technologies and transformations than can combat chronic diseases associated with aging. A4M offers continuing medical education, activities, and training through its advanced education entity (MMI).

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