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Article ID: 708123

Can we repair the brain? The promise of stem cell technologies for treating parkinson's disease

IOS Press

Cell replacement may play an increasing role in alleviating the motor symptoms of Parkinson's disease (PD) in future. Writing in a special supplement to the Journal of Parkinson's Disease, experts describe how newly developed stem cell technologies could be used to treat the disease and discuss the great promise, as well as the significant challenges, of stem cell treatment.

Released:
14-Feb-2019 2:05 PM EST
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Article ID: 707949

Mayo Clinic researchers develop more efficient system to reprogram stem cells

Mayo Clinic

Induced pluripotent stem cells, the workhorse of many regenerative medicine projects, start out as differentiated cells that are reprogrammed to pluripotent stem cells by exposure to a complex set of genetic cocktails.

Released:
12-Feb-2019 9:05 AM EST
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Article ID: 707668

In Their DNA: Rotator Cuff Stem Cells More Likely to Develop into Fat Cells

Wolters Kluwer Health: Lippincott Williams and Wilkins

Why are fat deposits more likely to occur after tears of the shoulder’s rotator cuff, compared to other types of muscle injuries? An increased propensity of stem cells within with rotator cuff muscles to develop into fat cells may explain the difference, reports a study in the February 6, 2019 issue of The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.

Released:
6-Feb-2019 2:05 PM EST
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Article ID: 707561

How Men Continually Produce Sperm — and How that Discovery Could Help Treat Infertility

University of California San Diego Health

Using a leading-edge technique, UC San Diego School of Medicine researchers defined the cell types in both newborn and adult human testes and identified biomarkers for spermatogonial stem cells, opening a path for new strategies to treat male infertility.

Released:
5-Feb-2019 1:05 PM EST
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Article ID: 707107

First US Patient in Novel Stem Cell Trial for Stroke Disability Enrolled at UTHealth

University of Texas Health Science Center at Houston

The first U.S. patient to participate in a global study of a stem cell therapy injected directly into the brain to treat stroke disability was enrolled in the clinical trial this week at The University of Texas Health Science Center at Houston (UTHealth).

Released:
25-Jan-2019 4:05 PM EST
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Article ID: 707059

Untangling Tau: Researchers Find a “Druggable Target” for Treating Alzheimer’s Disease

University of California San Diego Health

Using induced pluripotent stem cell-derived neurons from Alzheimer’s patients, UC San Diego researchers say cholesteryl esters — the storage product for excess cholesterol within cells — act as regulators of the protein tau, providing a new druggable target for the disease.

Released:
24-Jan-2019 5:05 PM EST
  • Embargo expired:
    24-Jan-2019 1:00 PM EST

Article ID: 706763

Sci-Fi to Reality: Superpowered Salamander May Hold the Key to Human Regeneration

University of Kentucky

Scientists at the Unviersity of Kentucky have assembled the entire genome of the Mexican Axolotl, the key to unlocking the secrets of regeneration with potential for life-changing clinical applications down the road.

Released:
18-Jan-2019 4:00 PM EST
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Article ID: 706672

UCLA scientists create a renewable source of cancer-fighting T cells

University of California, Los Angeles (UCLA), Health Sciences

A study by UCLA researchers is the first to demonstrate a technique for coaxing pluripotent stem cells — which can give rise to every cell type in the body and which can be grown indefinitely in the lab — into becoming mature T cells capable of killing tumor cells.

Released:
17-Jan-2019 1:05 PM EST
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  • Embargo expired:
    17-Jan-2019 11:00 AM EST

Article ID: 706580

New hope for stem cell approach to treating diabetes

Washington University in St. Louis

Researchers at Washington University School of Medicine in St. Louis have tweaked the recipe for coaxing human stem cells into insulin-secreting beta cells and shown that the resulting cells are more responsive to fluctuating glucose levels in the blood.

Released:
16-Jan-2019 11:00 AM EST

Article ID: 706619

NIH researchers rescue photoreceptors, prevent blindness in animal models of retinal degeneration

NIH, National Eye Institute (NEI)

Using a novel patient-specific stem cell-based therapy, researchers at the National Eye Institute (NEI) prevented blindness in animal models of geographic atrophy, the advanced “dry” form of age-related macular degeneration (AMD), which is a leading cause of vision loss among people age 65 and older. The protocols established by the animal study, published January 16 in Science Translational Medicine (STM), set the stage for a first-in-human clinical trial testing the therapy in people with geographic atrophy, for which there is currently no treatment.

Released:
16-Jan-2019 3:05 PM EST

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