Feature Channels: Stem Cells

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Released: 4-Nov-2024 7:00 AM EST
Espaço: Uma nova fronteira para explorar a terapia com células-tronco
Mayo Clinic

As células-tronco cultivadas em microgravidade a bordo da Estação Espacial Internacional (EEI) possuem qualidades únicas que poderão, um dia, ajudar a potencializar as novas bioterapias e a curar doenças complexas, de acordo com dois pesquisadores da Mayo Clinic. A análise da pesquisa pelo pesquisador Fay Abdul Ghani e pelo Dr. e Ph.D. Abba Zubair, publicada na NPJ Microgravity, descobriu que a microgravidade pode fortalecer o potencial regenerativo das células. O Dr. Zubair é especialista em medicina laboratorial e diretor médico do Centro de Bioterapias Regenerativas na Mayo Clinic, na Flórida. Abdul Ghani é um tecnólogo em pesquisa da Mayo Clinic. A microgravidade é a ausência de peso ou gravidade próxima a zero.

Released: 4-Nov-2024 7:00 AM EST
Espacio: Una nueva frontera para explorar la terapia con células madre
Mayo Clinic

Las células madre cultivadas en microgravedad a bordo de la Estación Espacial Internacional (EEI) poseen cualidades únicas que algún día podrán ayudar a potenciar las nuevas bioterapias y curar enfermedades complejas, según dos investigadores de Mayo Clinic. El análisis de la investigación por el investigador Fay Abdul Ghani y por el Dr. y Ph.D. Abba Zubair, publicado en NPJ Microgravity ha hallado que la microgravidad puede fortalecer el potencial regenerativo de las células. El Dr. Zubair es especialista en medicina de laboratorio y director médico del Centro de Bioterapias Regenerativas en Mayo Clinic, Florida. Abdul Ghani es tecnólogo de investigación en Mayo Clinic. La microgravedad es la ausencia o gravedad cercana a cero.

Released: 4-Nov-2024 3:00 AM EST
الفضاء: أفق جديد لاستكشاف العلاج بالخلايا الجذعية
Mayo Clinic

جاكسونفيل، فلوريدا — يقول باحثان من مايو كلينك إن الخلايا الجذعية التي تنمو في ظروف انعدام الجاذبية على متن محطة الفضاء الدولية (ISS) تتميز بخصائص فريدة قد تساهم في تسريع تطوير علاجات بيولوجية جديدة وعلاج الأمراض المعقدة في المستقبل. التحليل البحثي الذي أجرته فاي عبد الغني والدكتور عبا زبير، الحاصل على درجة الدكتوراه في الطب، والذي نُشر في مجلة NPJ Microgravity، يكشف أن انعدام الجاذبية يمكن أن يعزز من القدرة التجديدية للخلايا. يعد الدكتور زبير خبيرًا في الطب المخبري والمدير الطبي لمركز العلاج الحيوي التجديدي في مايو كلينك بفلوريدا. أما عبد الغني فهي تقنيّة بحثية في مايو كلينك. يعرف انعدام الجاذبية بكونه حالة من انعدام الوزن أو الجاذبية القريبة من الصفر.

Newswise: The Breadth of Breast Cell Types
Released: 31-Oct-2024 1:30 PM EDT
The Breadth of Breast Cell Types
University of New Mexico Comprehensive Cancer Center

October is Breast Cancer Awareness Month, and fittingly, University of New Mexico Comprehensive Cancer Center biologist Curt Hines, PhD, has published a pair of papers that comprehensively describe the twelve major types of cells in the human breast.

Released: 30-Oct-2024 12:00 PM EDT
Enhancing the Functionality of Mesenchymal Stem Cells: An Attractive Treatment Strategy for Metabolic Dysfunction-Associated Steatotic Liver Disease?
World Journal of Stem Cells

The intrinsic heterogeneity of metabolic dysfunction-associated fatty liver disease (MASLD) and the intricate pathogenesis have impeded the advancement and clinical implementation of therapeutic interventions, underscoring the critical dema

Released: 30-Oct-2024 12:00 PM EDT
MD Anderson Research Highlights for October 30, 2024
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

   
Released: 28-Oct-2024 12:00 PM EDT
Enhancing the Functionality of Mesenchymal Stem Cells: An Attractive Treatment Strategy for Metabolic Dysfunction-Associated Steatotic Liver Disease?
World Journal of Stem Cells

The intrinsic heterogeneity of metabolic dysfunction-associated fatty liver disease (MASLD) and the intricate pathogenesis have impeded the advancement and clinical implementation of therapeutic interventions, underscoring the critical dema

Newswise: Lab-Grown Pork Gets Support From Sorghum Grain
Released: 28-Oct-2024 9:30 AM EDT
Lab-Grown Pork Gets Support From Sorghum Grain
American Chemical Society (ACS)

Researchers publishing in ACS’ Journal of Agricultural and Food Chemistry have created a prototype cultured pork using a new material: kafirin proteins isolated from red sorghum grain.

Newswise: Advancing Care of a Devastating Disease Through Gene Therapy
Released: 28-Oct-2024 7:00 AM EDT
Advancing Care of a Devastating Disease Through Gene Therapy
University of California, San Francisco (UCSF)

A new international trial is investigating the efficacy and safety of gene therapy in patients with Hurler syndrome and will compare results of gene therapy against BMT which is the current standard of care. UCSF Benioff Children’s Hospitals are among three sites in the U.S. and seven in the world now enrolling patients for the clinical trial.

Newswise: NUS Making Bold Strides Towards a Synthetic Biology-Driven Future
Released: 27-Oct-2024 11:20 PM EDT
NUS Making Bold Strides Towards a Synthetic Biology-Driven Future
National University of Singapore (NUS)

The National University of Singapore (NUS) will be taking a significant leap forward in synthetic biology, leveraging its deep expertise and cutting-edge innovations to usher a new paradigm for green manufacturing, driven by this rapidly evolving field. Over the next six years, the University plans to dedicate substantial resources and efforts – estimated to value around S$120 million (US$90.6 million) - to firmly establish synthetic biology as a foundational pillar of NUS’ innovation ecosystem, driving transformative benefits for Singapore across multiple sectors.

Released: 26-Oct-2024 12:00 PM EDT
Gamma-aminobutyric acid enhances miR-21-5p loading into adipose-derived stem cell extracellular vesicles to alleviate myocardial ischemia-reperfusion injury via TXNIP regulation
World Journal of Stem Cells

BACKGROUNDMyocardial ischemia-reperfusion injury (MIRI) poses a prevalent challenge in current reperfusion therapies, with an absence of efficacious interventions to address the underlying causes. AIMTo investigate whether the extracellula

Released: 26-Oct-2024 12:00 PM EDT
Enhancing the functionality of mesenchymal stem cells: An attractive treatment strategy for metabolic dysfunction-associated steatotic liver disease?
World Journal of Stem Cells

The intrinsic heterogeneity of metabolic dysfunction-associated fatty liver disease (MASLD) and the intricate pathogenesis have impeded the advancement and clinical implementation of therapeutic interventions, underscoring the critical dema

Released: 26-Oct-2024 12:00 PM EDT
Emergence of the stromal vascular fraction and secretome in regenerative medicine
World Journal of Stem Cells

Recently, we read a mini-review published by Jeyaraman et al. The article explored the optimal methods for isolating mesenchymal stromal cells from adipose tissue-derived stromal vascular fraction (SVF). Key factors include tissue source, p

Released: 26-Oct-2024 12:00 PM EDT
Enhancing the Functionality of Mesenchymal Stem Cells: An Attractive Treatment Strategy for Metabolic Dysfunction-Associated Steatotic Liver Disease?
World Journal of Stem Cells

The intrinsic heterogeneity of metabolic dysfunction-associated fatty liver disease (MASLD) and the intricate pathogenesis have impeded the advancement and clinical implementation of therapeutic interventions, underscoring the critical dema

Released: 26-Oct-2024 12:00 PM EDT
Enhancing the functionality of mesenchymal stem cells: An attractive treatment strategy for metabolic dysfunction-associated steatotic liver disease?
World Journal of Stem Cells

The intrinsic heterogeneity of metabolic dysfunction-associated fatty liver disease (MASLD) and the intricate pathogenesis have impeded the advancement and clinical implementation of therapeutic interventions, underscoring the critical dema

Released: 26-Oct-2024 12:00 PM EDT
Enhancing the Functionality of Mesenchymal Stem Cells: An Attractive Treatment Strategy for Metabolic Dysfunction-Associated Steatotic Liver Disease?
World Journal of Stem Cells

The intrinsic heterogeneity of metabolic dysfunction-associated fatty liver disease (MASLD) and the intricate pathogenesis have impeded the advancement and clinical implementation of therapeutic interventions, underscoring the critical dema

Released: 26-Oct-2024 12:00 PM EDT
Bioengineering breakthroughs: The impact of stem cell models on advanced therapy medicinal product development
World Journal of Stem Cells

The burgeoning field of bioengineering has witnessed significant strides due to the advent of stem cell models, particularly in their application in advanced therapy medicinal products (ATMPs). In this review, we examine the multifaceted im

Newswise: Could a New Medical Approach Fix Faulty Genes Before Birth?
Released: 24-Oct-2024 2:00 PM EDT
Could a New Medical Approach Fix Faulty Genes Before Birth?
UC Davis Health

A new biomedical tool successfully delivers genetic material to edit faulty genes in developing fetal brain cells. This might stop disease progression of genetic-based neurodevelopmental conditions before birth.

Newswise: Yale School of Medicine Professors Elected to National Academy of Medicine
Released: 21-Oct-2024 12:05 PM EDT
Yale School of Medicine Professors Elected to National Academy of Medicine
Yale School of Medicine

Yale School of Medicine professors Erol Fikrig, MD, and Haifan Lin, PhD, have been elected to the National Academy of Medicine.

Newswise: Memorial Sloan Kettering Physician-Scientists Elected to the Prestigious National Academy of Medicine
21-Oct-2024 9:30 AM EDT
Memorial Sloan Kettering Physician-Scientists Elected to the Prestigious National Academy of Medicine
Memorial Sloan Kettering Cancer Center

Dr. Deb Schrag, Chair of the Department of Medicine, and Dr. Lorenz Studer, Director of the Center for Stem Cell Biology at Memorial Sloan Kettering Cancer Center (MSK), have been elected to the National Academy of Medicine (NAM), one of the highest honors bestowed upon scientists worldwide.



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