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Scientists Reveal How Mutations in Metabolism Can Drive Cancers

Yale Cancer Center scientists have identified mutations in metabolite-producing genes as a disruption of DNA repair. These mutation-driven “oncometabolites” may make cells more prone to developing cancer—but also more vulnerable to new cancer...
1-Jun-2020 12:15 PM EDT Add to Favorites

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Study Shows Clinical Evidence of Anti-Tumor Activity in Patients with Metastatic Castration-Resistant Prostate Cancer

Results of a Phase I clinical trial conducted by researchers at the Yale Cancer Center have shown that ARV-110, an androgen receptor PROTAC® protein degrader, demonstrates anti-tumor responses in patients with metastatic castration-resistant...
29-May-2020 8:00 AM EDT Add to Favorites

Study Shows Profound Benefit with Targeted Therapy for Patients with Early Stage NSCLC

According to findings led by researchers at Yale Cancer Center, treatment with the targeted therapy osimertinib following surgery significantly improves disease-free survival (DFS) in patients with early-stage, non-small cell lung cancer (NSCLC)...
28-May-2020 5:00 PM EDT Add to Favorites

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Study Demonstrates Impact of Both Inherited and Acquired Mutations on Cancer

The common belief that tumors arise via activation of a few genes that “drive” cancer development is unsupported by a widespread investigation into those genes and others in three large patient genetic databases, according to a study led by Yale...
14-May-2020 2:45 PM EDT Add to Favorites

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Study Shows Immunotherapy Prior to Surgery May Help Destroy High-Risk Breast Cancer

A new study led by Yale Cancer Center (YCC) researchers shows women with high-risk HER2-negative breast cancer treated before surgery with immunotherapy, plus a PARP inhibitor with chemotherapy, have a higher rate of complete eradication of cancer...
27-Apr-2020 9:00 AM EDT Add to Favorites

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Yale Cancer Center Announces Hematology Leadership Appointments

Yale Cancer Center announces the appointments of Thomas Prebet, M.D., Ph.D., as Disease Aligned Research Team (DART) Leader for Myeloid Malignancies and Amer Zeidan, MBBS, as Director of the Hematology Early Therapeutics Program.
20-Apr-2020 8:35 AM EDT Add to Favorites

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Study points to obesity as driver of pancreatic cancer

A new study led by Yale Cancer Center (YCC) researchers has demonstrated in mice that hormones released from the pancreas itself can advance pancreatic cancer — and that weight loss can stop this process in its early stages. The research was...
17-Apr-2020 8:20 AM EDT Add to Favorites

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First Test Using Immunotherapy Drug to Treat Advanced Lung Cancer Shows Benefit — And Future Promise

Researchers at Yale Cancer Center (YCC) have found that use of the checkpoint inhibitor pembrolizumab can extend life with very few side effects in this patient population.
13-Apr-2020 8:40 AM EDT Add to Favorites


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Our Experts on Newswise

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Five Ways to Lower Your Skin Cancer Risk

Experts at Yale Cancer Center say unless you take the right precautions, sun exposure (even if you don't get scorched) can damage your skin, causing wrinkles, age spots and even skin cancer.
22-Jun-2018 10:05 AM EDT

Yale Expert Discusses Treatment for Endometrial Cancer

Dr. Alesandro Santin Discusses Treatment for Endometrial Cancer
3-Apr-2018 3:55 PM EDT

Expert Speaks on Utilizing Information Technology to Address Oral Chemotherapy Challenges

Utilizing Information Technology to Address Oral Chemotherapy Challenges
26-Mar-2018 2:05 PM EDT

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Yale Expert Available to Speak on Medical Marijuana for Children with Cancer

12-Mar-2018 3:05 PM EDT

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Overcoming Resistance to Immunotherapy

For some cancer patients, the road to remission and healing can have its share of speed bumps. That’s particularly true of patients with non-small cell lung cancer (NSCLC) who develop a secondary, or acquired, resistance to immunotherapy, which...
27-Oct-2017 11:50 AM EDT

Daniel P. Petrylak, MD, on Urothelial Carcinoma: Results of the RANGE Trial

6-Oct-2017 3:05 PM EDT

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Yale Expert Wins Prestigious 2017 Warren Alpert Prize

6-Oct-2017 2:05 PM EDT

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Backed by Yale Cancer Center Research, FDA Approves New Immunotherapy Drug for Stomach Cancer

22-Sep-2017 4:30 PM EDT

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About

Yale Cancer Center combines a tradition of innovative cancer treatment and quality care for our patients. A National Cancer Institute (NCI) designated comprehensive cancer center for over 40 years, Yale Cancer Center is one of only 45 Centers in the nation.

Yale Cancer Center is a collaboration between nationally and internationally renowned scientists and physicians at Yale School of Medicine and Smilow Cancer Hospital at Yale-New Haven. This partnership enables the Center to provide the best approaches for prevention, detection, diagnosis, and treatment for cancer.

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Contacts

Anne Doerr
Director of Media Relations

anne.doerr@yale.edu

203-737-2629

Renee Gaudette
Director of Marketing & Public Affairs

renee.gaudette@yale.edu

203-671-8156

Scott Gettinger
Associate Professor of Medicine

scott.gettinger@yale.edu

Emily Montemerlo
Marketing Coordinator

emily.fenton@yale.edu

203-785-4343

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