Feature Channels: Epilepsy

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Released: 26-Oct-2015 11:05 AM EDT
Researchers Discover an Epilepsy Switch
University of Bonn

Scientists at the University of Bonn and the Hebrew University of Jerusalem (Israel) have decoded a central signal cascade associated with epileptic seizures. If the researchers blocked a central switch in epileptic mice, the frequency and severity of the seizures decreased. Using a novel technology, it was possible to observe the processes prior to the occurrence of epileptic seizures in living animals. The results are now being published in the journal "Nature Communications."

15-Oct-2015 4:00 PM EDT
Researchers Identify Gene That Increases Risk of Sudden Death in Patients with Mild Epilepsy
University Health Network (UHN)

Researchers in the Epilepsy Genetics Program of the Krembil Neuroscience Centre have discovered a gene mutation that increases the risk of sudden unexpected death in epilepsy (SUDEP) in patients with mild forms of the disease.

13-Oct-2015 2:00 PM EDT
Penn Researchers Develop Neuroimaging Method to Better Identify Epileptic Lesions in Complex Patients
Perelman School of Medicine at the University of Pennsylvania

PHILADELPHIA – Epilepsy affects more than 65 million people worldwide. One-third of these patients have seizures that are not controlled by medications. In addition, one-third have brain lesions, the hallmark of the disease, which cannot be located by conventional imaging methods. Researchers at the Perelman School of Medicine at the University of Pennsylvania have piloted a new method using advanced noninvasive neuroimaging to recognize the neurotransmitter glutamate, thought to be the culprit in the most common form of medication-resistant epilepsy. Their work is published today in Science Translational Medicine.

Released: 24-Sep-2015 2:05 PM EDT
Child Battles Hundreds of Daily Seizures, Finally Gets Relief Thanks to New Technology
Corewell Health

Brittany Brown has watched her daughter, Amaree, 6, struggle with hundreds of seizures every day for the past six years. Now, a new treatment is providing hope.

Released: 14-Sep-2015 2:05 PM EDT
UCI Study Uncovers Anticonvulsant Effects of Valproic Acid
University of California, Irvine

University of California, Irvine researchers with the School of Medicine have identified the mechanism by which valproic acid controls epileptic seizures, and by doing so, also revealed an underlying factor of seizures.

29-Jul-2015 1:05 PM EDT
Can Music Help People with Epilepsy?
American Psychological Association (APA)

The brains of people with epilepsy appear to react to music differently from the brains of those who do not have the disorder, a finding that could lead to new therapies to prevent seizures, according to research presented at the American Psychological Association’s 123rd Annual Convention.

   
Released: 29-Jul-2015 12:05 PM EDT
UAB’s ROSA Robot Guides New Epilepsy Procedure
University of Alabama at Birmingham

UAB is one of the only medical centers in the US using the ROSA robot in stereotactic EEG, to better find the origin of seizures in the brains of epilepsy patients prior to surgery.

Released: 14-Jul-2015 8:00 AM EDT
New Issue of Epilepsy Currents Highlights Psychosocial Outcomes, Emotional Awareness and a Master Plan for Seizure Dynamics
American Epilepsy Society (AES)

Epilepsy Currents is a literature surveillance publication, including brief expert commentary on abstracts in selected basic science and clinical topics selected by the editorial board.

Released: 5-Jul-2015 10:05 PM EDT
Research Breakthrough to Treat Girls-Only Epilepsy
University of Adelaide

An international team, led by a University of Adelaide genetics expert, has made a breakthrough discovery which is expected to help thousands of young girls worldwide who are suffering from a rare yet debilitating form of epilepsy.

Released: 19-Jun-2015 11:50 AM EDT
Scientists Identify Amino Acid that Stops Seizures in Mice
Johns Hopkins Medicine

An amino acid whose role in the body has been all but a mystery appears to act as a potent seizure inhibitor in mice, according to a study by researchers at Johns Hopkins.

Released: 8-Jun-2015 10:05 PM EDT
Been There? Done That? If You Are Sure, Thank Your ‘Memory Cells’
Cedars-Sinai

The witness on the stand says he saw the accused at the scene of the crime. Is he sure? How sure? The jury’s verdict could hinge on that level of certainty. Many decisions we make every day are influenced by our memories and the confidence we have in them. But very little is known about how we decide whether we can trust a memory or not. Cedars-Sinai researchers have identified a unique set of neurons in the medial temporal lobe, an area of the brain where memories and memory-based decisions are processed. They show that the activity of these neurons is indicative of the confidence by which a memory will be retrieved.

Released: 5-Jun-2015 11:05 AM EDT
UAB Researchers Unlock Mystery of Memory Loss in Epilepsy Patients
University of Alabama at Birmingham

New research from UAB identifies an epigenetic cause for why patients with temporal lobe epilepsy tend to have memory loss, and suggests a potential way to reverse that loss. The findings indicate the discovery may have implications for many other memory disorders.

Released: 14-May-2015 7:05 AM EDT
Every Bite You Take, Every Move You Make, Astrocytes Will Be Watching You
Universite de Montreal

Chewing, breathing, and other regular bodily functions that we undertake “without thinking” actually do require the involvement of our brain, but the question of how the brain programs such regular functions intrigues scientists. Arlette Kolta, a professor at the University of Montreal’s Faculty of Dentistry, has shown that astrocytes play a key role. Astrocytes are star-shaped glial cells in our brain. Glial cells are not neurons – they play a supporting role.

Released: 29-Apr-2015 1:05 PM EDT
Parents Describe Arduous Journey to Pediatric Epileptic Surgery When Their Child’s Disease Becomes Resistant to Anti-Seizure Meds
University of California, Los Angeles (UCLA), Health Sciences

Now, parents share their arduous and “circuitous” journey to get referrals for pediatric epilepsy surgery once their child’s disease stops responding to anti-seizure medications. The UCLA study sheds light on the difficulties parents face obtaining specialty and sub-specialty care for their children during an already stressful time.

Released: 20-Apr-2015 4:00 PM EDT
New Guidelines Inform Clinicians How to Treat a First Seizure
NYU Langone Health

Following a first seizure, physicians should discuss with patients whether it is appropriate to prescribe medication to reduce risk of another seizure, according to new guidelines released at the American Academy of Neurology meeting.

Released: 20-Apr-2015 9:00 AM EDT
Autism-Epilepsy Connection Explored in Four Studies
American Epilepsy Society (AES)

Epilepsy affects nearly 30 percent of all people with autism spectrum disorder (ASD), a neurobehavioral condition marked by impaired social and language development. Conversely, many patients with epilepsy display ASD-like behavior. Recent studies suggest that epileptic seizures impair the neural pathways needed for socialization, but the details of this process remain unclear.



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