Curated News: JAMA

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18-Dec-2014 6:00 PM EST
Maternal Supplementation with Multiple Micronutrients Compared With Iron-Folic Acid
JAMA - Journal of the American Medical Association

In Bangladesh, daily maternal supplementation of multiple micronutrients compared to iron-folic acid before and after childbirth did not reduce all-cause infant mortality to age 6 months, but did result in significant reductions in preterm birth and low birth weight, according to a study in the December 24/31 issue of JAMA.

11-Dec-2014 11:00 PM EST
Low-Glycemic Index Carbohydrate Diet Does Not Improve CV Risk Factors, Insulin Resistance
JAMA - Journal of the American Medical Association

In a study that included overweight and obese participants, those with diets with low glycemic index of dietary carbohydrate did not have improvements in insulin sensitivity, lipid levels, or systolic blood pressure, according to a study in the December 17 issue of JAMA.

11-Dec-2014 11:00 PM EST
Effectiveness of Drugs to Prevent Hepatitis Among Patients Receiving Chemotherapy
JAMA - Journal of the American Medical Association

Among patients with lymphoma undergoing a certain type of chemotherapy, receiving the antiviral drug entecavir resulted in a lower incidence of hepatitis B virus (HBV)-related hepatitis and HBV reactivation, compared with the antiviral drug lamivudine, according to a study in the December 17 issue of JAMA.

15-Dec-2014 2:00 PM EST
Mild Memory & Thinking Issues: What Works, What Doesn’t? U-M Experts Weigh the Evidence
Michigan Medicine - University of Michigan

For up to one in five Americans over age 65, getting older brings memory and thinking problems. It may seem like part of getting older - but officially, it’s called mild cognitive impairment or MCI. A new definitive look at the evidence about what works and what doesn’t in MCI should help doctors and the seniors they treat.

8-Dec-2014 1:00 PM EST
Majority of Women with Early-Stage Breast Cancer in U.S. Receive Unnecessarily Long Courses of Radiation
Perelman School of Medicine at the University of Pennsylvania

Two-thirds of women treated for early-stage breast cancer in the U.S. receive longer radiation therapy than necessary, according to a new study published in JAMA this week from Penn Medicine researchers Ezekiel J. Emanuel, MD, PhD, and Justin E. Bekelman, MD.

4-Dec-2014 10:00 PM EST
Region of Medical Residency Training May Affect Future Spending Patterns of Physician
JAMA - Journal of the American Medical Association

Among primary care physicians, the spending patterns in the regions in which their residency program was located were associated with expenditures for subsequent care they provided as practicing physicians, with those trained in lower-spending regions continuing to practice in a less costly manner, even when they moved to higher-spending regions, and vice versa, according to a study in the December 10 issue of JAMA, a theme issue on medical education.

4-Dec-2014 10:00 PM EST
Languages of Medical Residency Applicants Compared to Patients with Limited English
JAMA - Journal of the American Medical Association

An analysis of the non-English-language skills of U.S. medical residency applicants finds that although they are linguistically diverse, most of their languages do not match the languages spoken by the U.S. population with limited English proficiency, according to a study in the December 10 issue of JAMA, a theme issue on medical education.

4-Dec-2014 10:40 PM EST
Number of Medical Schools with Student-Run Free Clinics Has More Than Doubled
JAMA - Journal of the American Medical Association

There has been a doubling during the last decade in the number of U.S. medical schools that have student-run free clinics, with more than half of medical students involved with these clinics, according to a study in the December 10 issue of JAMA, a theme issue on medical education.

4-Dec-2014 10:00 PM EST
Emergency Department Resource Use by Supervised Residents vs. Attending Physicians Alone
JAMA - Journal of the American Medical Association

In a sample of U.S. emergency departments, compared to attending physicians alone, supervised visits (involving both resident and attending physicians) were associated with a greater likelihood of hospital admission and use of advanced imaging and with longer emergency department stays, according to a study in the December 10 issue of JAMA, a theme issue on medical education.

5-Dec-2014 1:10 PM EST
No Increase in Patient Deaths or Hospital Readmissions Following Restrictions to Medical Residents’ Hours
Perelman School of Medicine at the University of Pennsylvania

In the first year after the Accreditation Council for Graduate Medical Education (ACGME) reduced the number of continuous hours that residents can work, there was no change in the rate of death or readmission among hospitalized Medicare patients, according to a new study published in JAMA. The study was led by researchers at the Perelman School of Medicine at the University of Pennsylvania and The Children’s Hospital of Philadelphia.

4-Dec-2014 4:00 PM EST
Primary Care Doctors Report Prescribing Fewer Opioids for Pain
Johns Hopkins Bloomberg School of Public Health

Nine in 10 primary care physicians say that prescription drug abuse is a moderate or big problem in their communities and nearly half say they are less likely to prescribe opioids to treat pain compared to a year ago, new Johns Hopkins Bloomberg School of Public Health research suggests.

Released: 8-Dec-2014 4:00 PM EST
Higher Earning Clinicians Make More Money by Ordering More Procedures Per Patient Rather than by Seeing more Patients
University of California, Los Angeles (UCLA), Health Sciences

In results characterized as “very surprising,” UCLA researchers found for the first time that higher-earning clinicians make more money by ordering more procedures and services per patient rather than by seeing more patients, which may not be in patients’ best interest.

Released: 8-Dec-2014 1:45 PM EST
Hookah Smoking Increases Risk of Subsequent Cigarette Smoking Among Adolescents and Young Adults
Norris Cotton Cancer Center Dartmouth-Hitchcock Medical Center

A team of researchers at Dartmouth College and University of Pittsburgh found respondents who had smoked water pipe tobacco but not smoked cigarettes were at increased risk of cigarette smoking two years later as recently published online in JAMA Pediatrics.

26-Nov-2014 2:00 PM EST
Study Examines Use of Bone-Strengthening Drugs for Men Receiving ADT
JAMA - Journal of the American Medical Association

Although some guidelines recommend use of bisphosphonates (a class of drugs used to strengthen bone) for men on androgen deprivation therapy, an analysis finds that prescriptions for these drugs remains low, even for those men at high risk of subsequent fractures, according to a study in the December 3 issue of JAMA.

24-Nov-2014 9:00 AM EST
Patients Far More Likely to Have Imaging Scan if Seen by Non-Physician Provider
American College of Radiology (ACR)

Advanced practice clinicians, such as nurse practitioners and physician assistants, are 34 percent more likely than primary care physicians to prescribe an imaging exam for patients, according to a Harvey L. Neiman Health Policy Institute study published in JAMA Internal Medicine.

Released: 19-Nov-2014 4:00 PM EST
Vanderbilt Study Finds More Breast Cancer Patients Opting for Mastectomy
Vanderbilt University Medical Center

Far more breast cancer patients are choosing to undergo mastectomy, including removal of both breasts, instead of choosing breast conservation surgery even when they have early stage disease that is confined to one breast, a Vanderbilt study shows. In the past decade, there have also been marked trends toward higher proportions of women opting for breast reconstruction.

Released: 17-Nov-2014 2:00 PM EST
Testing of ER Patients for Heart Attack in Absence of Symptoms Widespread
UT Southwestern Medical Center

Emergency rooms are testing many patients for markers of acute coronary syndrome who show no signs of having suffered a heart attack, UT Southwestern Medical Center researchers have found.

13-Nov-2014 10:00 AM EST
New Study Finds Routine Imaging Screening of Diabetic Patients for Heart Disease Is Not Effective
Intermountain Medical Center

Routine heart imaging screenings for people with diabetes at high risk to experience a cardiac event, but who have no symptoms of heart disease, does not help them avoid heart attacks, hospitalization for unstable angina or cardiac death, according to a major new study.

13-Nov-2014 11:00 PM EST
Risk of Death May Be Higher if Heart Attack Occurs in a Hospital
JAMA - Journal of the American Medical Association

Prashant Kaul, M.D., of the University of North Carolina, Chapel Hill, and colleagues conducted a study to define the incidence and treatment and outcomes of patients who experience a certain type of heart attack during hospitalization for conditions other than acute coronary syndromes. The study appears in the November 19 issue of JAMA, a cardiovascular disease theme issue.

13-Nov-2014 11:20 PM EST
Overall Death Rate From Heart Disease Declines, Although Increase Seen for Certain Types
JAMA - Journal of the American Medical Association

Matthew D. Ritchey, D.P.T., of the Centers for Disease Control and Prevention (CDC), Atlanta, and colleagues examined the contributions of heart disease subtypes to overall heart disease mortality trends during 2000-2010. The study appears in the November 19 issue of JAMA, a cardiovascular disease theme issue.

13-Nov-2014 11:00 PM EST
Device’s Potential as Alternative to Warfarin for Stroke Prevention in Patients with A-Fib
JAMA - Journal of the American Medical Association

Vivek Y. Reddy, M.D., of the Icahn School of Medicine at Mount Sinai, New York, and colleagues examined the long-term efficacy and safety, compared to warfarin, of a device to achieve left atrial appendage closure in patients with atrial fibrillation. The study appears in the November 19 issue of JAMA, a cardiovascular disease theme issue.

13-Nov-2014 11:00 PM EST
Use of Beta-Blockers for Certain Type of Heart Failure Linked With Improved Survival
JAMA - Journal of the American Medical Association

Lars H. Lund, M.D., Ph.D., of the Karolinska Institutet, Stockholm, Sweden, and colleagues conducted a study to examine whether beta-blockers are associated with reduced mortality in heart failure patients with preserved ejection fraction (a measure of how well the left ventricle of the heart pumps with each contraction).The study appears in the November 19 issue of JAMA, a cardiovascular disease theme issue.

13-Nov-2014 11:00 PM EST
Prevalence, Risk of Death of Type of Coronary Artery Disease in Heart Attack Patients
JAMA - Journal of the American Medical Association

Duk-Woo Park, M.D., of the University of Ulsan College of Medicine, Seoul, Korea, and Manesh R. Patel, M.D., of the Duke Clinical Research Institute, Durham, N.C., and colleagues investigated the incidence, extent, and location of obstructive non-infarct-related artery (IRA) disease and compared 30-day mortality according to the presence of non-IRA disease in patients with ST-segment elevation myocardial infarction.

14-Nov-2014 10:00 AM EST
Half of STEMI Heart Attack Patients May Have Additional Clogged Arteries
Duke Health

A blocked artery causes a deadly kind of heart attack known as STEMI, and a rapid response to clear the blockage saves lives. But in more than half of cases studied recently by Duke Medicine researchers, one or both of the patient’s other arteries were also obstructed, raising questions about whether and when additional procedures might be undertaken.

13-Nov-2014 11:00 PM EST
Aspirin or Blood Pressure Medication Before and After Surgery Does Not Reduce Risk of AKI
JAMA - Journal of the American Medical Association

In patients undergoing noncardiac surgery, neither aspirin nor clonidine (a medication primarily used to treat high blood pressure) taken before and after surgery reduced the risk of acute kidney injury, according to a study appearing in JAMA. The study is being released to coincide with its presentation at the American Society of Nephrology’s annual Kidney Week meeting.

13-Nov-2014 11:00 PM EST
Use of Antibiotic Following Kidney Transplantation Does Not Prevent Virus Infection
JAMA - Journal of the American Medical Association

Among kidney transplant recipients, a 3-month course of the antibiotic levofloxacin following transplantation did not prevent the major complication known as BK virus from appearing in the urine. The intervention was associated with an increased risk of adverse events such as bacterial resistance, according to a study appearing in JAMA. The study is being released to coincide with its presentation at the American Society of Nephrology’s annual Kidney Week meeting.

12-Nov-2014 11:00 AM EST
Diabetic Eye Screenings via Telemedicine Show Value for Underserved Communities
University of Alabama at Birmingham

Eye screenings via medicine of people with diabetes in underserved communities revealed that one in five had early stage diabetic retinopathy, according to a new study by a research consortium including investigators at UAB.

10-Nov-2014 4:00 PM EST
Soldiers at Increased Risk for Suicide Within a Year of Psychiatric in-Patient Treatment
Uniformed Services University of the Health Sciences (USU)

Soldiers hospitalized with a psychiatric disorder have a significantly elevated risk for suicide in the year following hospital discharge, according to findings published in JAMA Psychiatry, Nov. 12, 2014. Although this has long been known in the civilian sector, it has never before been studied in the military population.

12-Nov-2014 3:30 PM EST
Depression, Overwhelming Guilt in Preschool Years Linked to Brain Changes
Washington University in St. Louis

A key brain region involved in emotion is smaller in older children diagnosed with depression as preschoolers, and predicts risk of later recurrence, according to researchers at Washington University School of Medicine in St. Louis.

6-Nov-2014 4:40 PM EST
Administration of Tdap Vaccine During Pregnancy Not Linked with Preterm Delivery
JAMA - Journal of the American Medical Association

Among approximately 26,000 women, receipt of the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine during pregnancy was not associated with increased risk of preterm delivery or small-for-gestational-age birth or with hypertensive disorders of pregnancy, although a small increased risk of being diagnosed with chorioamnionitis (an inflammation of the membranes that surround the fetus) was observed, according to a study in the November 12 issue of JAMA.

Released: 6-Nov-2014 11:00 AM EST
Is Violent Injury a Chronic Disease? U-M Study Suggests So, and May Aid Efforts to Stop the Cycle
Michigan Medicine - University of Michigan

Teens and young adults who get seriously injured in an assault are nearly twice as likely as their peers to end up back in the emergency room for a violent injury within the next two years, a new University of Michigan study finds. The researchers call this repeating pattern of violent injury a reoccurring disease.

5-Nov-2014 4:00 PM EST
Number of Young Patients with Newly Diagnosed Colorectal Cancer Anticipated to Nearly Double By 2030
University of Texas MD Anderson Cancer Center

November 5, 2014 – In the next 15 years, more than one in 10 colon cancers and nearly one in four rectal cancers will be diagnosed in patients younger than the traditional screening age, according to researchers at The University of Texas MD Anderson Cancer Center.

3-Nov-2014 1:00 PM EST
Medicare May Need to Expand Options for Behavioral Weight Loss Counseling in Primary Care Settings, According to Penn Research Review
Perelman School of Medicine at the University of Pennsylvania

An important addition to the “eat less, move more” strategy for weight loss lies in behavioral counseling to achieve these goals. But research on how primary care practitioners can best provide behavioral weight loss counseling to obese patients in their practices — as encouraged by the Centers for Medicare and Medicaid Services (CMS) — remains slim, according to a systematic review of this topic published today in JAMA. The study was led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

3-Nov-2014 1:00 PM EST
Medicare May Need to Expand Options for Behavioral Weight Loss Counseling in Primary Care Settings, According to Penn Research Review
Perelman School of Medicine at the University of Pennsylvania

An important addition to the “eat less, move more” strategy for weight loss lies in behavioral counseling to achieve these goals. But research on how primary care practitioners can best provide behavioral weight loss counseling to obese patients in their practices — as encouraged by the Centers for Medicare and Medicaid Services (CMS) — remains slim, according to a systematic review of this topic published today in JAMA. The study was led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

4-Nov-2014 9:50 AM EST
In Human Clinical Trial, UAB to Test Drug Shown to Completely Reverse Diabetes in Human Islets and Mice
University of Alabama at Birmingham

A recently awarded grant will fund a human clinical trial in type 1 diabetes beginning in early 2015 to see if verapamil will have an effect in humans by attacking the disease where it occurs. Meanwhile, more small molecule drugs at UAB are in development.

   
Released: 4-Nov-2014 7:00 AM EST
New Use for an Old Drug Could Impact Cirrhosis Patients
Baylor Scott and White Health

A common drug used to clean a person’s bowels before a colonoscopy could become the future standard of care for patients with acute hepatic encephalopathy (HE), a mental disorientation problem that affects up to one in two cirrhosis patients. The finding comes from new research, known as the “HELP Clinical Trial,” that appeared in JAMA Internal Medicine on Sept. 22.

30-Oct-2014 11:00 AM EDT
Novel Tinnitus Therapy Helps Patients Cope with Phantom Noise
Washington University in St. Louis

Patients with tinnitus hear phantom noise and are sometimes so bothered by the perceived ringing in their ears, they have difficulty concentrating. A new therapy does not lessen perception of the noise but appears to help patients cope better with it in their daily lives, according to new research at Washington University School of Medicine in St. Louis.

27-Oct-2014 2:50 PM EDT
Placebo Better Than 'Watchful Waiting' When Treating Young Children's Coughs
Penn State Health

Both agave nectar and a placebo were more effective than no treatment for young children's cough symptoms, according to researchers at Penn State College of Medicine. The findings suggest that a placebo could help children more than "watchful waiting."

23-Oct-2014 1:00 PM EDT
Genetic Predisposition to Elevated LDL-C Associated With Narrowing of the Aortic Valve
JAMA - Journal of the American Medical Association

In an analysis that included approximately 35,000 participants, genetic predisposition to elevated low-density lipoprotein cholesterol (LDL-C) was associated with aortic valve calcium and narrowing of the aortic valve, findings that support a causal association between LDL-C and aortic valve disease, according to a study appearing in JAMA. The study is being released to coincide with its presentation at the Canadian Cardiovascular Congress.

Released: 24-Oct-2014 10:00 AM EDT
JAMA Viewpoint: Price Displays for Physicians – Which Price Is Right?
Johns Hopkins Berman Institute of Bioethics

In response to research indicating that healthcare costs go down when physicians are shown the cost of tests at the time of ordering, a pair of medical ethicists at Johns Hopkins have outlined the ethical issues that need consideration when designing and displaying prices for physicians.



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