Researchers at The Saban Research Institute of Children’s Hospital Los Angeles have identified an unsuspected and critical role of the MDM2 oncogene in promoting expression of the MYCN oncogene that is required for growth and survival of retinoblastoma cells. Their results are published in the October 17 online edition of the Nature journal Oncogene.
Cal State LA has received a national award from INSIGHT Into Diversity magazine for its success in fostering diversity and inclusion in the School of Nursing. The INSIGHT's 2016 Health Professions Higher Education Excellence in Diversity (HEED) Award recognizes U.S. medical, dental, pharmacy, osteopathic, nursing and allied health schools that demonstrate an outstanding commitment to diversity and inclusion.
Undergoing a computer tomographic angiography was a better motivator to get people with suspected coronary artery disease to adopt healthier lifestyle practices than an exercise electrocardiography and stress test.
The Children’s Discovery and Innovation Institute at Mattel Children’s Hospital UCLA announces the 2016-2017 recipients of the Harry Winston Fellowships.
Robert A. Figlin, MD, will serve as Deputy Director of the Integrated Oncology Service Line at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute. Previously, he was director of the Hematology Oncology Division at the institute.
Seven-year-old Rey Ahumada should be jumping and playing outside like most other children his age. Instead, he’s fighting leukemia and “stuck in a bubble,” says his mom, an admissions clerk at UCLA Medical Center, Santa Monica. “That word, ‘cancer,’” she adds. “We need to put an end to it.” With that as a goal, UCLA Health is presenting sponsor of the Leukemia & Lymphoma Society’s Oct. 22 “Light the Night Walk” in Los Angeles. Jassmine will be carrying a red lantern in support of Rey and other patients with blood cancers who are hoping for a cure. Individuals who wish to commemorate a loved one lost to cancer will carry yellow lanterns, while cancer survivors will carry white, signifying the power of research.
Fourteen California State University campuses have been named to the 2015 President's Higher Education Community Service Honor Roll—the highest federal honor that universities can receive for their commitment to community service, service-learning, and civic engagement.
A study by a multidisciplinary team of researchers from Children’s Hospital Los Angeles sheds further light on the role of the cytokine TGFβ1 in the growth of neuroblastoma, and suggests the possibility for a small molecule drug/antibody combinatorial therapy to treat this cancer.
Cedars-Sinai has awarded nearly $700,000 to scientists developing new treatments and technologies — such as advanced genetic profiling and biomedical sensors that can be worn at home — to deliver individualized healthcare to patients.
The Milky Way Project is a crowd-sourced research effort that allows citizen scientists to identity nebulae, stars and more in imagery taken by NASA’s Spitzer Space Telescope.
Think “scientific research” and one may imagine doctors, Ph.D.s or technicians toiling away in the lab. But many people don’t realize that nurses do research too. Karen Grimley, chief nursing executive at UCLA Health and assistant dean in the UCLA School of Nursing, discussed why the concept of nurses as researchers may be surprising to some, although the work they do is vital to improving the health and well-being of patients
UCLA and four other institutions have been awarded a $13.9 million grant to evaluate treatment strategies for older adults with depression who have not responded to medications.
Rather than taking medication, a growing number of people who suffer from chronic pain, epilepsy and drug cravings are zapping their skulls in the hopes that a weak electric current will jolt them back to health. Here's the issue: Until now, scientists have been unable to look under the hood of this DIY therapeutic technique to understand what is happening.
The UCLA Lung Transplant program performed its 1,000th transplant surgery in mid-September, becoming the first program on the West Coast, and one of only seven centers nationwide, to achieve this milestone.
UCLA experts are available for interviews about opioid-related topics
The University of Southern California (USC) Norris Comprehensive Cancer Center has partnered with Springbok Cares to provide a unique Virtual Reality initiative for patients in the Adolescent and Young Adult Cancer program at USC.
Researchers at the University of Southern California will demonstrate how using wearable technology and smartphones can improve cancer treatment at a White House event on Oct. 3. The USC project will be one of the participants in the Cancer Moonshot exhibit championed by Vice President Joe Biden. Researchers aim to provide doctors with real-time patient data from wearable technology and patient-reported experiences so that physicians can base their treatment decisions on objective measures rather than just subjective and episodic observations.
Why do some people lead a perfectly healthy lifestyle yet still die young? A new international study suggests that the answer lies in our DNA.
Time is of the essence when getting people stricken with acute ischemic strokes to treatment. And the use of stent retrievers — devices that remove the blood clot like pulling a cork out of a wine bottle Current professional guidelines recommend that stent retrievers be used to remove blood clots from stroke patients within six hours for people to benefit. But new research finds that the procedure has benefits for people up to 7.3 hours following the onset of a stroke.
Building on the results of a recent Cedars-Sinai Heart Institute study published just six months ago, the Department of Defense has awarded a $10 million grant to fund a cardiac cell therapy trial for patients diagnosed with a common but difficult-to-treat form of heart failure.
UCLA Health experts are available to discuss a wide variety of topics of interest for the month of October.
Many know Botox as a trendy way to get rid of wrinkles, but the popular drug — made from botulinum neurotoxin (BoNT) — can do more than just fill lines.
New report finds that across 800 films, representation of gender, race/ethnicity, LGBT status, disability still lags behind population norms.
Paola Mardo is the 2016-2017 Sony Pictures Entertainment (SPE) Fellow and will study film criticism as part of USC Annenberg’s Masters in Arts Journalism program.
Human factors researchers developed the Game User Experience Satisfaction Scale (GUESS), a psychometrically validated instrument that measures satisfaction on key factors such as playability, narratives, creative freedom, social connectivity, and visual aesthetics.
Researchers use hospital emergency room data from around the country to document emergence of E. coli strain that fights medication. They recommend development of new antibiotics and treatment guidelines.
Using newly updated mouse models, USC researchers demonstrated the impactful preventive properties of 9-cis retinoic acid against lymphedema. Currently, there is no cure for lymphedema, a swelling of the extremities that most commonly occurs after treatment for cancer.
California State University, Dominguez Hills (CSUDH) has received a $2.6 million grant from the U.S. Department of Education (ED) to create “Project Accelerate” to improve the learning, persistence, and overall success of CSUDH students, while decreasing their time to earning a degree.
Professor Ashish Sinha and a team of international researchers used their analysis of stalagmites recovered from a cave deep in central China to not only map over 640,000 years of history of the Asian Monsoon—the longest and most accurate record to date—but also change the understanding of how ice ages terminate.
David Warburton, MD, of Children’s Hospital Los Angeles (CHLA) has been awarded more than $2.3 million from the Department of Defense for the development of an innovative endoscopic device for performing noninvasive, quantitative analysis of lung epithelial cell metabolism during lung injury.
Cal State LA is one of the best regional universities in the nation, according to the 2017 U.S. News & World Report Best Colleges edition released today, Sept. 13. Cal State LA was ranked #14 among public regional universities in the West, a jump from last year’s #18 ranking.
In a first-of-its-kind look at human kidney development, researchers at The Saban Research Institute of Children’s Hospital Los Angeles have isolated human nephron progenitor (NP) cells. Their results may offer a future way to foster renal regeneration after chronic kidney failure or acute injury.
From infancy, we learn by watching other people, then use those memories to help us predict outcomes and make decisions in the future. Now a UCLA–Caltech study has pinpointed the individual neurons in the brain that support observational learning.
Recommendations to move at least 30 minutes a day have made recent headlines, but living a heart healthy lifestyle incorporates other factors too. UCLA Health offers these tips.
After receiving a stem cell injection into his spine, Kris Boesen, who was paralyzed from his neck to his toes after a car accident, is regaining movement in his extremities and hope for increased independence.
Scientists at Cedars-Sinai have developed a new way to identify which prostate cancer patients are likely to develop aggressive types of the disease even if their tumors at first appear to be lower risk. The new findings could help physicians prescribe the most effective treatments for each patient based on how genes are activated in the individual tumor.
Jill and Frank Fertitta Hall, the fifth and largest USC Marshall School of Business facility, will officially open on Sept. 7. The 104,000 square-foot, five-story building adds much-needed classroom and student services space to USC Marshall’s undergraduate program.
A paper just published in Human Factors: The Journal of the Human Factors and Ergonomics Society, describes a correlation between an operator’s working memory and ability to sustain attention and a phenomenon known as cognitive lock-up, when an individual focuses longer on an initial failure event than on subsequent failures.
Papers and panels will address human-centered issues in cyber operations, including situation awareness, vigilance, task-switching, and training.
Many human factors experts - some of whom are attending the 2016 Annual Meeting - are studying effects of automation in vehicles to help ensure the safe application of technology for drivers, passengers, pedestrians, and infrastructure.
Researchers at the Institute for the Developing Mind at Children’s Hospital Los Angeles have analyzed current gene-disease findings to understand why people with neurodevelopmental and mental illness often have physical disorders.
Research uncovers true properties of rare radioactive metal that could provide key to targeted cancer drugs.
A research team at Children’s Hospital Los Angeles has generated functional human and mouse tissue-engineered liver from adult stem and progenitor cells. Tissue-engineered Liver (TELi) was found to contain normal structural components such as hepatocytes, bile ducts and blood vessels.
Being overweight increases the chances of premature death, said Jonathan Samet of USC. His statement is backed by a four-continent effort involving 239 studies and data from 10.6 million people. The study — one of the largest to date — runs counter to the results of a JAMA, which found that being overweight actually adds to one’s life span.
Biomedical investigators at Cedars-Sinai have identified an enzyme found in all human cells that alerts the body to invading bacteria and jump-starts the immune system. In their study, published in the peer-reviewed medical journal Cell, the investigators provide clues to unraveling some of the mysteries surrounding the human immune system, which defends the body against harmful microbes such as bacteria.
Children’s Hospital Los Angeles (CHLA) has been recognized by the National Association of Epilepsy Centers (NAEC) as a Level 4 epilepsy center, providing the highest–level medical and surgical evaluation and treatment for patients with complex epilepsy.
UCLA Health experts are available to discuss a wide variety of topics of interest, with a focus on back-to-school issues, for the month of September.
Cedars-Sinai resident neurosurgeon Lindsey Ross, MD, a member of the medical center’s Neurological Surgery Residency Program, has won a coveted position as a 2016-2017 White House Fellow. Starting this week, Ross will spend the next year in Washington working in the U.S. Department of Health and Human Services, and participating in roundtable discussions with top government leaders, including President Barack Obama and Vice President Joe Biden.
Permanent brain damage from a stroke may be reversible thanks to a developing therapeutic technique. The novel approach combines transplanted human stem cells with a special protein that the U.S. Food and Drug Administration already approved for clinical studies in new stroke patients.
For the first time in Los Angeles County history, more Latinos than whites are being diagnosed with testicular cancer, a malady once regarded as a white man’s disease. This Q&A focuses on testicular cancer: who is at risk, why they are at risk and what preventive measures can be taken.
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