Focus: Hidden - Michigan

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After collecting data on a leukemia-affected family for nearly a decade, Children’s Hospital of Michigan, Detroit Medical Center (DMC), Hematologist and Wayne State University School of Medicine Professor of Pediatrics Madhvi Rajpurkar, M.D., joined an international team of genetic researchers in an effort to track down a mutation partly responsible for causing the disease. Their findings, recently published in one of the world’s leading science journals, have “major implications” for better understanding the genetic basis of several types of cancer, including leukemia.

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A University of Michigan researcher and his colleagues are forecasting an average but still large "dead zone" in the Gulf of Mexico this year.

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A team of researchers from Wayne State University was recently issued a U.S. patent (# 8,998,808) on a technology that will offer anesthesiologists better methods for monitoring and managing patients in the operating room.

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The University of Michigan Frankel Cardiovascular Center performs 500th procedure to fix heart valves using tiny tubes threaded through blood vessels.

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Adults across the country share the same top concern about the new alcohol-on-the-go product: potential misuse among underage youth.

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Variations in the amount of oxygen in Earth’s atmosphere significantly altered global climate throughout the planet’s history. Efforts to reconstruct past climates must include this previously overlooked factor, a new University of Michigan-led study concludes.

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We've all been there: We eat an entire sleeve of fat-free, low-calorie cookies and we're stuffing ourselves with more food 15 minutes later.

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It started out as a treatment for arthritis. But steered by science, it could become a first new approach in two decades for treating the damage that diabetes inflicts on the kidneys of millions of people.

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The Department of Energy’s (DOE’s) Office of Science recently announced its selection of 50 scientists from across the nation to receive its Early Career Research Program award. Eranda Nikolla, Ph.D., assistant professor of chemical engineering in Wayne State University’s College of Engineering, was selected out of 620 submissions to receive a five-year, $750,000 award for her proposal, Nanostructured, Targeted Layered Metal Oxides as Active and Selective Heterogeneous Electrocatalysts for Oxygen Evolution.

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Thomas Werner, an assistant professor of biological sciences at Michigan Tech, has bridged the miniscule and the massive in an effort to better understand the mechanisms behind several unique features of fruit fly genes.

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Having a stroke ages a person’s brain function by almost eight years, new research finds – robbing them of memory and thinking speed as measured on cognitive tests.

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Old rocks hold on to their secrets. Now, a geophysicist at Michigan Technological University has unlocked clues trapped in the magnetic signatures of mineral grains in those rocks. These clues will help clear up the murky history of the Earth’s early core.

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Day in and day out, millions of people with diabetes test their blood sugar levels. And many may wonder if all the careful eating, exercise and medication it takes to keep those levels under control is really worth it. A major new study should encourage them to keep going -- and prompt them to work with their doctors on reducing their cardiovascular risk.

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A survey of women with breast cancer found that nearly half considered having a double mastectomy. But of those who considered it, only 37 percent knew that the more aggressive procedure does not improve survival for women with breast cancer.

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Despite stereotypes about college students resorting to black-market Ritalin to help them cram for exams, young people are actually most likely to start misusing prescription stimulant drugs in their high school years, according to new University of Michigan Medical School research.

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Can a routine hospital stay upset the balance of microbes in our bodies so much that it sets some older people up for a life-threatening health crisis called sepsis? A new study suggests this may be the case.

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Funding from the Mark Cuban Foundation, run by the well-known owner of the Dallas Mavericks, will allow University of Michigan scientists and physicians to study how human growth hormone may aid recovery from an ACL tear.

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Why does schizophrenia happen, and how can we improve treatment for it? A Michigan team and their colleagues will take a new approach to addressing these questions by searching for genetic clues in postmortem brain tissues of people with and without schizophrenia.

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As drought continues, and demand grows, researchers like Alex Mayer from Michigan Technological University are looking to new models to improve the Rio Grande region's drought resiliency.

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The U-M Food Allergy Center will now be named the Mary H. Weiser Food Allergy Center and the Weiser family is also making significant financial commitments to the U-M Food Allergy Center.

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Researchers in the U.S. and Germany will take a unique look at diabetes complications by studying Pima Indians, a population heavily impacted by kidney damage caused by diabetes.

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Nearly 10 years after the Livonia preschooler Leah James lost her battle to an inoperable brain tumor, she has inspired a children’s book designed to help other families like hers cope with a cancer diagnosis.

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Mark A. Lumley, Ph.D., professor and director of the clinical psychology Ph.D. program at Wayne State University, recently received the 2015 Blue Cross Blue Shield of Michigan Foundation McDevitt Excellence in Research Award in the area of clinical research.

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For decades, scientists have known that ET-743, a compound extracted from a marine invertebrate called a mangrove tunicate, can kill cancer cells. The drug has been approved for use in patients in Europe and is in clinical trials in the U.S.

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Teens in the U.S. have more availability of mental health care than they did two years ago, but access is not equal in all communities.

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Obesity may be tougher on male immune systems than females, a new study in mice suggests.

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In a major advance in precision medicine, an international collaboration of researchers found 90 percent of castration resistant metastatic prostate cancers harbored some kind of genetic anomaly that could drive treatment choices.

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Most people see defects as flaws. A few Michigan Technological University researchers, however, see them as opportunities. Twin boundary defects may present an opportunity to improve lithium-ion batteries.

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As more Baby Boomers are screened for hepatitis C, a patient risk prediction model developed by the University of Michigan Health System, may help doctors target costly medications to those most likely to develop serious liver issues.

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Why do some cancer cells break away from a tumor and travel to distant parts of the body? A team of oncologists and engineers from the University of Michigan teamed up to help understand this crucial question.

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A class of FDA-approved cancer drugs may be able to prevent problems with brain cell development associated with disorders including Down syndrome and Fragile X syndrome, researchers at the University of Michigan Life Sciences Institute have found.

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A recent clinical trial, published in the New England Journal of Medicine and co-authored by the Children’s Hospital of Michigan, Detroit Medical Center (DMC) Chief of Critical Care and Wayne State University School of Medicine Professor of Pediatrics Kathleen L. Meert, M.D., shows that “therapeutic hypothermia” is no more effective than maintaining normal body temperature in children who’ve suffered cardiac arrest before being hospitalized.

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Screening to identify Type 2 diabetes followed by early treatment could result in substantial health benefits, according to new research that combined large scale clinical observations and innovative computer modelling.

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A new urine-based test improved prostate cancer detection – including detecting more aggressive forms of prostate cancer – compared to traditional models based on prostate serum antigen, or PSA, levels, a new study finds.

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Many parents of children age 5-17 don’t discuss behavioral or emotional issues that could be signs of potential health problems with their doctors.

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Researchers have developed and tested a new tool that searches for the most common genetic anomalies seen in cancer. The assay demonstrates the ability to make gene sequencing easier over a large volume of samples.

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Researchers at Michigan Technological University are working on 3D bioprinting synthetic tissue that could help regenerate nerve cells in patients with spinal cord injuries.

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Climate helps drive the erosion process that exposes economically valuable copper deposits and shapes the pattern of their global distribution, according to a new study from researchers at the University of Idaho and the University of Michigan.

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A simple reminder via electronic health record systems linked to significantly higher HPV vaccine completion rates.

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Arginine, a common amino acid found naturally in foods, breaks down dental plaque, which could help millions of people avoid cavities and gum disease, researchers at the University of Michigan and Newcastle University have discovered

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What’s the only thing worse than having a urinary catheter when you’re in the hospital? Having one and getting a urinary tract infection (UTI) – or worse – as a result. Now, a new detailed guide gives doctors and nurses information to help decide which hospital patients may benefit from a urinary catheter – and which ones don’t.

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Wayne State University researchers have been awarded a $1.8 million grant from the National Institute for Allergy and Infectious Diseases of the NIH to garner more genomic information about herpes simplex virus 1 that could lead to new anti-herpes treatments.

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People with depression or bipolar disorder often feel their thinking ability has gotten “fuzzy”, or less sharp than before their symptoms began. Now, researchers have shown in a large study that effect is indeed real – and rooted in brain activity differences that show up on advanced brain scans.

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For any biotechnology company, getting the first product out of the lab and into patients in a clinical trial is a major milestone, and a cause for celebration. But not many of those companies get to celebrate on the campus where the idea for their product was born and first developed.

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Study reports outcomes for three boys who became the first in the world to benefit from 3D printed devices that saved their lives at U-M's C.S. Mott Children's Hospital.

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Nearly half of foodborne illnesses in the U.S. from 1998 through 2008 have been attributed to contaminated fresh produce. Prevention and control of bacterial contamination on fresh produce is critical to ensure food safety. The current strategy remains industrial washing of the product in water containing chlorine. However, due to sanitizer ineffectiveness there is an urgent need to identify alternative antimicrobials, particularly those of natural origin, for the produce industry.

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In certain types of cancer, nerves and cancer cells enter an often lethal and intricate waltz where cancer cells and nerves move toward one another and eventually engage in such a way that the cancer cells enter the nerves.

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The threat of landslides and mudslides remains high across much of Nepal's high country, and the risk is likely to increase when the monsoon rains arrive this summer, according to a University of Michigan researcher.

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