Alternative DNA Repair Mechanism Could Provide Better Treatment for Neuroblastoma in Kids
Michigan Medicine - University of MichiganTargeting DNA repair pathways could provide new treatment options for children with high-risk cancer
Targeting DNA repair pathways could provide new treatment options for children with high-risk cancer
The cost of school sports keeps many children from participating, according to the latest University of Michigan Mott Children’s Hospital National Poll on Children’s Health.
When a bird swoops down and grabs a caterpillar devouring your backyard garden, you might view it as a clear victory for natural pest control.
President Obama will outline various executive actions and legislative proposals during the State of the Union address Jan. 20. University of Michigan experts are available to offer analysis.
The highest-ranking U.S. official to visit Cuba in five decades will lead a delegation Wednesday to Havana to begin talks about normalizing relations. The trip is part of President Obama's effort to ease the embargo with the communist nation.
A new human embryonic stem cell line containing the genetic mutation for adrenoleukodystrophy (ALD), and neurons grown from those cells, are now helping scientists study the condition -- thanks to an embryo donated by a couple seeking to avoid passing the disease to their son.
Combining insecticide-treated bed nets with vaccines and other control measures may provide the best chance at eliminating malaria, which killed nearly 600,000 people worldwide in 2013, most of them African children.
A key to victory in battle, according to Chinese general and military strategist Sun Tzu, is to know your enemy. In the current fight against whooping cough resurgence, perhaps the biggest obstacle is an incomplete understanding of its underlying causes, according to a University of Michigan population ecologist.
Researchers at the University of Michigan Comprehensive Cancer Center analyzed the global landscape of a portion of the genome that has not been previously well-explored. This analysis opens the door to discovery of thousands of potential new cancer biomarkers.
Over a 12-year period, the prevalence of falls among older adults appeared to be on the rise, a new nationally representative study says.
New research from the University of Michigan Comprehensive Cancer Center helps explain why pancreatic cancer is so lethal, with fewer than a third of patients surviving even early stage disease.
A new study from researchers at the University of Michigan Comprehensive Cancer Center characterizes the genetic underpinnings of a rare type of breast tumor called phyllodes tumors, offering the first comprehensive analysis of the molecular alterations at work in these tumors.
Innovative scoring system uses “Ann Arbor GVHD score” to better predict how patients will respond, minimize side effects
Pope Francis on Thursday visits the Philippines—one of the most devoutly Catholic countries in the world. Professors at the University of Michigan are available to discuss the pope's leadership challenges and the Church's influence in the country and other parts of Asia.
Researchers at the University of Michigan have identified how a promising drug in clinical trials for the treatment of obesity and related metabolic disorders improves the metabolism of sugar by generating a new signal between fat cells and the liver.
Wearable technology allows 24-year-old with a total artificial heart to wait at home for a heart transplant. It's the latest milestone in efforts to replace the failing heart.
After a forest fire, logging companies often follow to do what is called salvage logging—salvaging the timber that has not been completely destroyed by the fire. The economic benefit is clear. But the ecological effects are unknown.
Photonic booms--flashes that are faster than the speed of light--may turn out to help illuminate a variety of astronomical objects such as asteroids and the moon.
Was Beethoven's music influenced by a cardiac arrhythmia?
Learning how good bacteria in the gut feast on complex carbohydrates could end your break up with bread.
An exhaustive analysis of data from more than 40,000 cases of brain trauma in children – published by the authoritative New England Journal of Medicine – provides convincing evidence that protecting children in advance from head injuries is the key to reducing their severity.
Study indicates that alternatives to hysterectomy are being underused and that treatment guidelines are often not followed.
Many parents don’t follow guidelines that call for using rear-facing car seats until age 2, according to National Poll on Children’s Health data
One of the mysteries in cancer biology is how one protein, TGF-beta, can both stop cancer from forming and encourage its aggressive growth. Now, researchers at the University of Michigan Comprehensive Cancer Center have uncovered a key gene that may explain this paradox and provide a potential target for treatment.
Fewer new cases of end-stage renal disease are being reported in the United States and mortality rates are declining, indicating that patients on dialysis or with a kidney transplant are living longer.
A Henry Ford Hospital study, presented recently at the American Association of Hip and Knee Surgeons meeting in Dallas, found that injecting a newer long-acting numbing medicine called liposomal bupivacaine into the tissue surrounding the knee during surgery may provide a faster recovery and higher patient satisfaction.
By analyzing the DNA and RNA of lung cancers, researchers at the University of Michigan Comprehensive Cancer Center found that patients whose tumors contained a large number of gene fusions had worse outcomes than patients with fewer gene fusions. In addition, the researchers identified several new genetic anomalies that occur in lung cancer, including in patients with a history of smoking.
A Wayne State University interdisciplinary research team in the Eugene Applebaum College of Pharmacy and Health Sciences has made a surprising discovery: older, more mature motorists — who typically are better drivers in many circumstances — are much worse than their younger counterparts when texting while driving.
For up to one in five Americans over age 65, getting older brings memory and thinking problems. It may seem like part of getting older - but officially, it’s called mild cognitive impairment or MCI. A new definitive look at the evidence about what works and what doesn’t in MCI should help doctors and the seniors they treat.
In 2014, more teens use e-cigarettes than traditional, tobacco cigarettes or any other tobacco product—the first time a U.S. national study shows that teen use of e-cigarettes surpasses use of tobacco cigarettes.
A national survey of students in U.S. middle schools and high schools shows some important improvements in levels of substance use.
Most parents agree their children should be ready to move out of the pediatrician’s office into adult-focused care by age 18 – but just 30 percent actually make that transition by that age, according to the University of Michigan C.S. Mott Children’s Hospital National Poll on Children’s Health.
The Patient Protection and Affordable Care Act may have provided health care insurance to an estimated 20 million Americans who lacked coverage, but it has not eased the demand on the nation’s emergency departments. In fact, since the law’s passage, reliance upon the nation’s emergency rooms for non-emergency care has increased.
It's not unusual for people to use war metaphors such as "fight" and "battle" when trying to motivate patients with cancer.
Since its launch in April, 477,000 Michiganders have signed up for a new Medicaid health insurance option offered by the state, called the Healthy Michigan Plan. Now, University of Michigan researchers will study how well the new plan works, and advise the state government on how well it’s living up to what lawmakers intended.
Using indium tin oxide, a common coating in modern electronics, an engineer developed a biosensor that enables simultaneous electrical measurements and visual observation.
Despite years of effort to help American seniors with high blood pressure, heart disease, or diabetes get their blood pressure, cholesterol and blood sugar under control, new research shows wide gaps between older people of different ethnic backgrounds in all three of these key health measures.
The debate continues over whether recent police responses that resulted in citizen deaths were justified or excessive. Northern Michigan University's criminal justice program has purchased a use-of-force simulator. Such units are typically reserved for limited use in police academies or professional training. They provide realistic law enforcement scenarios designed to enhance rapid problem-solving skills. NMU's simulator will give students early and frequent exposure to some 700 potential scenarios and update/improve criminal justice education, which "has been stagnant for too long."
As if holiday travel isn't stressful enough. Now University of Michigan researchers say we're likely sharing that already overcrowded airline cabin with countless tiny creatures including house dust mites.
Ask any woman: urinary tract infections are painful and unpredictable. University of Michigan researchers identify genes to help fight the infections that are becoming resistant to antibiotics.
One of the most common infections contracted in hospitals, C. difficile is often a cause of disease and death among the elderly. Patients with C. difficile often have recurrent infections over prolonged periods of time, making treatment of this disease challenging. In the United States alone, there are approximately half a million C. difficile cases annually, with a mortality rate greater than 2.5 percent. A new, $3.2 million NIH grant aims to assess the effectiveness of a new treatment for the disease.
A common prostate cancer therapy should not be used in men whose cancer has not spread beyond the prostate, according to a new study led by researchers at Henry Ford Hospital. Results appear in European Urology.
Birds fly into windows all the time, often killing themselves. The student chapter of The Wildlife Society at Michigan Tech is researching these collisions at buildings on campus, hoping to develop some protective solutions.
Reduced water availability and quality, floods and problems related to heat stress are some of the potential impacts cities face with a changing climate.
A technology that started in a University of Michigan Medical School lab may soon help lung disease patients around the world breathe a little easier, by helping their doctors make a clearer diagnosis and more individualized treatment plan.
Patients with head and neck cancer who used antacid medicines to control acid reflux had better overall survival, according to a new study from the University of Michigan Comprehensive Cancer Center.
Charles Darwin noted more than 150 years ago that animals on the Galapagos Islands, including finches and marine iguanas, were more docile than mainland creatures. He attributed this tameness to the fact that there are fewer predators on remote islands.
As much as two-thirds of Earth's carbon may be hidden in the inner core, making it the planet's largest carbon reservoir, according to a new model that even its backers acknowledge is "provocative and speculative."
Despite clear signs that their memory and thinking abilities have gone downhill, more than half of seniors with these symptoms haven’t seen a doctor about them, a new study finds.