Information on functional status—whether or not a person can carry out routine daily tasks independently—improves the ability to predict risk of death in patients undergoing surgery, according to a study in the July issue of Anesthesia & Analgesia.
During the wars in Iraq and Afghanistan, US combat support hospitals treated at least 650 children with severe, combat-related head injuries, according to a special article in the July issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Wolters Kluwer.
More Americans are using soft contact lenses—especially daily disposable lenses—and taking advantage of new designs targeting vision problems that were difficult to correct with previous contact lenses, reports the July issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Wolters Kluwer.
House calls, a long-running option dating back to the early days of medicine, can be used in a new way to improve geriatric care and lower costs, says a report issued last week from the Centers for Medicare & Medicaid Services (CMS).
Stress hormones often given to patients to treat the side effects of therapy may cause a subset of breast cancers to become treatment-resistant.
Rorke-Adams, 86, was the only female president in the 188-year history of Philadelphia General Hospital. She went on to become acting chair of Pathology at CHOP, president of the American Association of Neuropathology, a Penn professor, and an international expert on pediatric brain tumors and shaken baby syndrome. And she was the guardian of a sample of Albert Einstein's brain until donating the slide to the Mutter Museum in 2008.
New studies and commentary directed toward improving the quality of health care and ensuring patient safety are assembled in the special June issue of the Southern Medical Journal, official journal of the Southern Medical Association. The journal is published for the society by Wolters Kluwer.
Neurodegenerative diseases, such as Lou Gehrig’s, Parkinson's, Alzheimer's, and Huntington's disease, all result in part from a defect in autophagy – one way a cell removes and recycles misfolded proteins and pathogens. Researchers show for the first time that the formation of ephemeral compartments key in this process require actin polymerization by a complex of seven proteins, which creates “comet tails.”
Researchers discover that a protein called Taranis could hold the key to a good night’s sleep.
Although a goal of Medicaid expansion under the Affordable Care Act was to provide Medicaid patients with a source of nonemergency care outside of hospital emergency departments (EDs), researchers suggest that these newly enrolled patients will likely continue to look to EDs for treatment of chronic diseases and other nonemergency issues, despite state attempts to impose fees on ED visits. Health policy researchers suggest in a new Perspective published in the New England Journal of Medicine that patient-centered medical homes may be more effective in reducing the number of Medicare patients seeking nonemergency care in EDs than increasing the cost of the visits.
Steven D. Douglas, M.D., received the Paradigm Builder Lectureship Award of the International Society for NeuroVirology on June 4. The Award recognizes Douglas’s 40 years of work in the biology of immune cells and HIV infection.
University of Pennsylvania School of Nursing Names Dr. Therese Richmond Associate Dean for Research and Innovation
Workers involved in nearly every step of the modern food industry are at increased risk of occupational illness/injury and death, compared to other industries, reports a study in the July Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine (ACOEM).
When trying to enroll in a health insurance plan through HealthCare.gov during the first open enrollment period of the Affordable Care Act’s (ACA) health insurance marketplaces, young adults were confused by unfamiliar health insurance terms, concerned about the affordability of plan options, and unsure how to seek good primary care. Those findings were among the results of a study led by researchers at the Perelman School of Medicine at the University of Pennsylvania that followed a group of well-educated young adults as they shopped for health insurance on HealthCare.gov.
Short boys are three times more likely than short girls to receive recombinant human growth hormone treatment for idiopathic short stature (ISS), even though in a general pediatric population, equal proportions of both genders had ISS.
Frederic D. Bushman, PhD, a widely recognized leader in the fields of microbiology and gene therapy, has been named the new chair of the department of Microbiology in the Perelman School of Medicine at the University of Pennsylvania.
A hormone that regulates blood sugar levels may be the key to reducing the risk of acute respiratory distress syndrome in obese patients.
According to a new study, women experiencing difficulty with time management, attention, organization, memory, and problem solving – often referred to as executive functions – related to menopause may find improvement with a drug already being used to treat attention deficit hyperactivity disorder (ADHD).
The NCCN Oncology Research Program (ORP) received a $2-million grant from Boehringer Ingelheim Pharmaceuticals, Inc. to facilitate studies of afatinib in non-small cell lung cancer.
The well-known "fight or flight" response is part of the inborn series of defense/fear responses activated in reaction to threats. Understanding the steps of the defense cascade can help in forming effective treatments for patients dealing with persistent aftereffects of trauma, according to a review in the Harvard Review of Psychiatry. The journal is published by Wolters Kluwer.
More than one-third of counties in the Unites States are located more than 50 miles from the nearest gynecologic oncologist, making access to specialty care for ovarian and other gynecologic cancers difficult for nearly 15 million women.
Community health workers (CHW) are expected to be a growing and vital part of healthcare delivery in the United States as the Affordable Care Act is fully implemented. A slate of steps detailing how CHW programs can maximize their effectiveness and impact on patients and healthcare spending is provided in a new perspective piece in The New England Journal of Medicine.
University of the Sciences board chairman Marvin Samson has announced leadership changes within the USciences board of trustees and the University administration.
New approaches, based on body mass index (BMI) or other simple measures, are needed to improve assessment of obesity in adolescents with physical disabilities, reports a paper in the American Journal of Physical Medicine & Rehabilitation, the official journal of the Association of Academic Physiatrists. The journal is published by Wolters Kluwer.
In his new book, Swarthmore College Political Scientist Dominic Tierney explains why the United States is struggling on the battlefield, how Washington can resolve a failing war, and how America can start winning again.
Older patients who received stem cells from younger, unrelated donors with higher numbers of so-called killer T cells (CD8 cells) had significantly reduced risk of disease relapse and improved survival compared to those who received stem-cells from donors with low numbers of CD8 cells, including older matched siblings.
Researchers say that the ability to "diagnose" the skills teen drivers lack may provide opportunities for better driving practice in a safe environment, so that teens are better prepared to navigate hazardous situations when they take to the road alone.
Botulinum toxin could offer an effective new treatment for two forms of neuropathy—pain caused by different types of nerve injury, according to an experimental study published in Anesthesia & Analgesia.
Young infants who can "resettle" themselves after waking up are more likely to sleep for prolonged periods at night, according to a video study in the June Journal of Developmental & Behavioral Pediatrics, the official journal of the Society for Developmental and Behavioral Pediatrics. The journal is published by Wolters Kluwer.
Professor Afaf Meleis of the University of Pennsylvania School of Nursing co-led a Lancet commission on women and health. Here are the findings from the commission's report.
Rev-erbα is a transcription factor that regulates a cell's internal clock and a new study describes how it regulates the clock in most cells in the body and metabolic genes in the liver in distinct ways.
Eating less late at night may help curb the concentration and alertness deficits that accompany sleep deprivation, according to results of a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania that will be presented at SLEEP 2015, the 29th annual meeting of the Associated Professional Sleep Societies LLC.
Physical activities, such as walking, as well as aerobics/calisthenics, biking, gardening, golfing, running, weight-lifting, and yoga/Pilates are associated with better sleep habits, compared to no activity, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania. In contrast, the study shows that other types of physical activity – such as household and childcare -- work are associated with increased cases of poor sleep habits. The full results of the study (Abstract #0246) will be presented during the poster session on Monday, June 8, at SLEEP 2015, the 29th annual meeting of the Associated Professional Sleep Societies LLC, June 6-10, in Seattle, WA.
When the T cells of your immune system are forced to deal over time with cancer or a chronic infection they become exhausted - less effective at attacking and destroying invaders. While the PD-1 protein pathway has long been implicated as a primary player in T cell exhaustion, a major question has been whether PD-1 actually directly causes exhaustion. A new paper seems to, at least partially, let PD-1 off the hook.
– Individuals with a higher level of moral reasoning skills showed increased gray matter in the areas of the brain implicated in complex social behavior, decision making, and conflict processing as compared to subjects at a lower level of moral reasoning, according to new research from the Perelman School of Medicine and the Wharton School of the University of Pennsylvania in collaboration with a researcher from Charité Universitätsmediz in Berlin, Germany. The team studied students in the Masters of Business Administration (MBA) program at the Wharton School. The work is published in the June 3rd edition of the journal PLOS ONE.
The Children's Hospital of Philadelphia announces that Patrick K. FitzGerald has been appointed to the newly created position of VIce President for Entrepreneurship & Innovation.
Scientists at The Wistar Institute have found a protein that circulates in the blood that appears to be more accurate at detecting non-small cell lung cancer (NSCLC) than currently available methods used for screening.
Wistar Institute scientists have identified how a specific variant of a key protein complex found in human cells called condensin can reorganize a cell’s genetic architecture in such a way as to promote senescence, making it an important facilitator in a cell’s anticancer ability.
NCCN and Pfizer will elicit grant proposals for quality improvement and education in metastatic breast cancer.
Karen Knudsen will become the ninth woman in an illustrious group of 68 leaders of NCI-designated Cancer Centers around the nation.
The National Comprehensive Cancer Network® (NCCN®) will host Emerging Issues in Tissue Allocation, on June 8, 2015, at the National Press Club in Washington, DC.
A new phase 3 study in some of the most difficult-to-treat patients, women with endocrine-resistant disease, showed that the newly approved drug, palbociclib, more than doubled the time to cancer recurrence for women with hormone-receptor (HR+) positive metastatic breast cancer.
People with dementia and other forms of cognitive impairment (CI) have altered responses to pain, with many conditions associated with increased pain sensitivity, concludes a research review in PAIN®, the official publication of the International Association for the Study of Pain. The journal is published by Wolters Kluwer.
As in adults, migraine surgery is effective for selected adolescent patients with severe migraine headaches that don't respond to standard treatments, reports a study in the June issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Researchers are exploring new approaches to designing prosthetic hands capable of providing "sensory feedback." Advances toward developing prostheses with a sense of touch are presented in a special topic article in the June issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
Cerebral palsy is the most common cause of childhood disability in the world, but is understudied, especially in developing countries. An ongoing international partnership in Botswana has done the first rigorous study of CP outcomes in Africa.
With demand for primary care expected to increase sharply over the next five years– due to passage of the Affordable Care Act (ACA), population growth and aging – the role of advanced-practice nurses or nurse practitioners (NPs) is also increasing. But a new study illustrates how federal policies influence the NP workforce and practice, and how misalignment of those policies with state mandates can affect workforce supply and patient access to care.
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