An international panel of experts from four renowned diabetes research centers, including UT Southwestern Medical Center, has reviewed current literature and is recommending a pivotal change in treatment of Type 2 diabetes to focus on obesity first and glucose control second.
A potential breakthrough in the early detection of the neck, head and anal cancers linked to human papilloma viruses (HPV) has emerged. It is based on a highly specific diagnostic test that appears to indicate cancer, and predict its course, from just a pinprick of blood.
As climate and commercial threats intensify, WHO-UNICEF-Lancet Commission presses for radical rethink on child health
The first ever global trends for adolescent insufficient physical activity show that urgent action is needed to increase physical activity levels in girls and boys aged 11 to 17 years. The study, published in The Lancet Child & Adolescent Health journal and produced by researchers from the World Health Organization (WHO), finds that more than 80% of school-going adolescents globally did not meet current recommendations of at least one hour of physical activity per day – including 85% of girls and 78% of boys.
Scientists from Germany and the United States have unveiled the results of a newly-completed
A new analysis co-led by The Johns Hopkins University identified 25 United States counties that are most likely to experience measles outbreaks in 2019. The analysis combined international air travel volume, non-medical exemptions from childhood vaccinations, population data and reported measles outbreak information.
Bill Kochevar, who was paralyzed below his shoulders in a bicycling accident, is believed to be the first person with quadriplegia in the world to have arm and hand movements restored with the help of two temporarily implanted technologies.
Optical coherence tomography (OCT) provides safe and improved guidance for patients undergoing percutaneous coronary intervention to treat coronary artery disease, according to results from the ILLUMIEN III: OPTIMIZE PCI trial.
New research offers unprecedented insights into the causes of childhood diarrhea, the second-leading cause of death of children worldwide, and suggests that the role of pathogens has been vastly underestimated.
A new study from Washington University in St. Louis suggests eight interventions that will help create healthier and more sustainable cities of the future, built to reduce the negative impacts of pollution, climate change, noise and crime.
A three-part series published in The Lancet and released in conjunction with the United Nations quantifies health gains achieved if cities were designed so that shops, facilities, work and public transportation were within walking distance of most residents.In part three of the series, researchers tackle how to implement timely research into city design, planning and policy to improve the health of a city’s residents.
Results from an international, randomized study show that an implanted nerve stimulator significantly improves symptoms in those with central sleep apnea, without causing serious side effects.
Being overweight increases the chances of premature death, said Jonathan Samet of USC. His statement is backed by a four-continent effort involving 239 studies and data from 10.6 million people. The study — one of the largest to date — runs counter to the results of a JAMA, which found that being overweight actually adds to one’s life span.
With publications in prestigious medical journals and multimillion dollar federal grants, UNC faculty have shown they are committed to moving the fields of HIV prevention, treatment and cure research forward.
Greater efforts should be made to actively monitor physical activity as a risk factor in clinical practice, finds a new study from the Brown School at Washington University in St. Louis.
In a paper published today in a special physical activity series of The Lancet, the Coordinated Approach to Child Health (CATCH) program developed by researchers at The University of Texas Health Science Center at Houston (UTHealth) was identified as an excellent example of an evidence-based physical activity intervention that has been successfully scaled up to affect population health.
Ahead of the Summer Olympic Games in London four years ago, researchers reported that physical inactivity was a global pandemic that required urgent action. With the 2016 Games looming, University of California San Diego School of Medicine investigators report little change in activity levels worldwide.
Research into Africa's first 'screen-and-treat' programme for hepatitis B suggests the initiative may reduce deadly complications of the virus.
Adding a novel monoclonal antibody therapy called olaratumab to traditional chemotherapy increased median survival by nearly a year in patients with advanced sarcoma, according to a multicenter clinical trial led by researchers at Columbia University Medical Center and NewYork-Presbyterian.
Researchers from Penn Medicine and other institutions found that treating metastatic thyroid cancer patients harboring a BRAF mutation with the targeted therapy vemurafenib —originally approved for melanoma patients with the mutation—showed promising anti-tumor activity in a third of patients. The results were published in this week’s Lancet Oncology.
Hospital admissions for a short-term and avoidable complication of diabetes have risen by 39 per cent in the last ten years, a new analysis has concluded.
A research paper published in The Lancet Infectious Diseases reported that the human papillomavirus (HPV) vaccine is safe and efficacious across a wide age range of women. The international study found that it protects against HPV infection in women older than 26 years.
An article published on July 6, 2016 in The Lancet ranks viral hepatitis infections – specifically both Hepatitis B (HBV) and Hepatitis C (HCV) – as the seventh leading cause of death worldwide in 2013, up from tenth in 1990. …hepatitis C is a critical public health concern that, despite the consistent release of research stating its increasing adverse impact on public health, continues to see woeful underfunding for prevention and treatment initiatives to curtail its spread.
Gay, bisexual and other men who have sex with men continue to have disproportionately high burdens of HIV infection in countries of low, middle and high income around the world, a new study led by the Johns Hopkins Bloomberg School of Public Health suggests.
Drinking piping hot coffee, tea and the caffeine-infused beverage yerba mate probably causes cancer, the World Health Organization announced Wednesday.
To protect human health, Endocrine Society members called on the European Commission to adopt science-based policies for regulating endocrine-disrupting chemicals in an opinion piece published today in The Lancet Diabetes & Endocrinology.
Scientists have discovered a unique pattern of scarring in the brains of deceased service members who were exposed to blast injury that differs from those exposed to other types of head injury. This new research was published online June 9 in Lancet Neurology, “Characterisation of Interface Astroglial Scarring in the Human Brain after Blast Exposure: a Post-mortem Case Series.”
A large worldwide study has found that, contrary to popular thought, low-salt diets may not be beneficial and may actually increase the risk of cardiovascular disease (CVD) and death compared to average salt consumption.
Meilan Han, M.D., an associate professor of internal medicine at the University of Michigan and the medical director of the U-M Women’s Respiratory Health Program, is the lead author on a new report that set out to provide a comprehensive view of COPD care in the U.S.
A new paper looks at how MRI and a clear understanding of the functional anatomy around the prostate can allow radiation oncologists to plan a course of treatment for patients with prostate cancer that spares these critical structures.
Every hospital’s ICU has treated them – the critically ill patients who spend weeks going from crisis to crisis, never quite getting better enough to get out of the ICU, but never quite dying. Now, research shows they really are a different kind of patient.
Compared to the nicotine patch and a placebo, the smoking cessation aids varenicline (marketed as Chantix in the U.S.) and bupropion (Zyban) do not show a significant increase in neuropsychiatric adverse events, reports an international team of researchers in a study published online April 22 in the journal The Lancet.
George Washington University's Dr. Michael S. Irwig published a review article in The Lancet Diabetes & Endocrinology journal on testosterone therapy for transgender men, calling for more research.
By spending less than $5 per person on essential health care services such as contraception, medication for serious illnesses and nutritional supplements, millions of maternal and child lives could be saved every year, according to a new analysis led by the Johns Hopkins Bloomberg School of Public Health.
Since 1980, the number of adults with diabetes worldwide has quadrupled from 108 million to 422 million in 2014, according to a new study published in The Lancet. The findings provide the most comprehensive estimates of worldwide diabetes trends to date and show that diabetes is fast becoming a major problem in low and middle income countries.
An investigational stem cell therapy derived from patients’ own blood marrow significantly improved outcomes in patients with severe heart failure, according to a study from the Cedars-Sinai Heart Institute.
More walkable neighborhoods, parks and public transit could all reduce your chance of becoming one of the 600 million adults who battle obesity worldwide, according to researchers at University of California, San Diego School of Medicine. The study, recently published online in The Lancet, found a neighborhood’s design plays a critical role in physical activity and could help reduce non-communicable diseases, such as obesity, diabetes and cardiovascular disease.
End-stage heart failure patients treated with stem cells harvested from their own bone marrow experienced 37 percent fewer cardiac events - including deaths and heart failure hospital admissions - than a placebo-controlled group, according to a new study. Results from ixCELL-DCM, the largest cell therapy clinical trial for treating heart failure to date, will be presented at the 2016 American College of Cardiology annual meeting and published online in The Lancet on April 4.
A landmark study published this month in the leading medical journal, The Lancet, reports the discovery of a blood test that can predict whether someone is likely to develop tuberculosis (TB) disease, long before the disease manifests.
A new study examines fertility issues in male and female childhood cancer survivors who had received chemotherapy. The study found that while most female survivors still have a good chance of conceiving, male survivors are significantly less likely to father children.
Most high-risk lung cancer patients might not need annual low-dose computed tomography (LDCT) screenings if they are cleared of disease in their initial test, according to a study led by a Duke Cancer Institute researcher.
In what investigators say is a surprise finding, results of a new study appear to strongly affirm the effectiveness of prescribing the anti-tuberculosis drug isoniazid alone — in place of the standard four-drug regimen — to prevent TB and reduce death in people with advanced HIV/AIDS infections. Those with HIV and AIDS are highly susceptible to TB.
The number one killer of HIV patients in resource-limited areas, including parts of Africa and India, is tuberculosis (TB), underscoring the need for optimal treatments and effective strategies to address this deadly co-infection. But TB is harder to detect in HIV-infected patients and diagnostic test results take time, so many healthcare providers prescribe multi-drug TB treatments as a precaution. However, for the first time, findings from a large, randomized clinical trial show that this aggressive approach does not save more lives, researchers from Penn Medicine and other institutions report in The Lancet.
Two widely used targeted therapy drugs approved by the FDA for the treatment of metastatic kidney cancer—sorafenib and sunitinib—are no more effective than a placebo in preventing return of the disease to increase life spans of patients suffering from advanced kidney cancer after surgery, according to a new multi-institutional study in the Lancet led by a researcher at the Abramson Cancer Center (ACC) of the University of Pennsylvania.
An imbalance of certain gut microbes appears to be the underlying cause of a frequently fatal intestinal illness in premature babies, according to new research led by Washington University School of Medicine in St. Louis.
Vitamin D supplementation during pregnancy may lead to stronger bones in babies born during the winter months, a new Southampton study has shown.
Researchers seeking to better understand how our genes contribute to stroke risk have completed what is believed to be the largest and most comprehensive review of the human genome to identify genes that predispose people to ischemic stroke, the cause of approximately 85 percent of all strokes.
Lung cancer is the most common cause of cancer-related death in the United States resulting in more than 158,000 deaths each year. With a 5-year survival rate at only 18 percent, the development of new and improved treatment options is needed. Moffitt Cancer Center researchers are leading the way in the creation of novel therapies. Most recently, Moffitt, in conjunction with partner institutions, initiated a multicenter phase 1b clinical trial to determine the safety and efficacy of a new drug combination for non-small cell lung cancer that stimulates a patient’s immune system to target and kill cancer cells.
Vascular surgery appears to be safer than stenting for patients over 70 years of age with carotid stenosis, or a blockage of the carotid arteries in the neck, according to new findings published in the Lancet.
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