Feature Channels: Alzheimer's and Dementia

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15-Sep-2010 12:55 PM EDT
Mild Memory Loss Is Not a Part of Normal Aging
RUSH

Simply getting older is not the cause of mild memory lapses often called senior moments, according to a new study by researchers at the Rush Alzheimer’s Disease Center. The study found that even the very early mild changes in memory that are much more common in old age than dementia are caused by the same brain lesions associated with Alzheimer’s disease and other dementias.

3-Sep-2010 1:30 PM EDT
Compounds Fend Off Alzheimer’s Disease Amyloid Pathology
UC San Diego Health

A team of scientists, led by University of California, San Diego School of Medicine researchers, has synthesized hundreds of new compounds with the potential of reducing the production of the A-beta 42 peptide, a primary component of Alzheimer’s disease (AD).

31-Aug-2010 3:25 PM EDT
Memory Problems More Common in Men?
American Academy of Neurology (AAN)

A new study shows that mild cognitive impairment (MCI) may affect more men than women. The research is published in the September 7, 2010, print issue of Neurology®, the medical journal of the American Academy of Neurology.

31-Aug-2010 4:40 PM EDT
Mild Cognitive Impairment is More Common in Men
Mayo Clinic

A new Mayo Clinic study found that the prevalence of mild cognitive impairment was 1.5 times higher in men than in women.

24-Aug-2010 12:00 PM EDT
Brain Exercises May Slow Cognitive Decline Initially, But Speed Up Dementia Later
American Academy of Neurology (AAN)

New research shows that mentally stimulating activities such as crossword puzzles, reading and listening to the radio may, at first, slow the decline of thinking skills but speed up dementia later in old age. The research is published in the September 1, 2010, online issue of Neurology®, the medical journal of the American Academy of Neurology.

30-Aug-2010 11:30 AM EDT
Scientists Identify Protein That Spurs Formation of Alzheimer’s Plaques
Rockefeller University

Scientists have discovered how the cancer drug Gleevec attacks beta-amyloid, the primary component of senile plaques in Alzheimer's disease. The finding suggests that drugs modeled on Gleevec could provide new treatments for this disease.

26-Aug-2010 5:00 PM EDT
Home-Based Intervention May Provide Some Benefit to Patients with Dementia and Their Caregivers
JAMA - Journal of the American Medical Association

An intervention that targeted modifiable stressors in the home of patients with dementia resulted in better outcomes for the patients and their caregivers at 4 months, but not at 9 months, although the caregivers perceived greater benefits, according to a study in the September 1 issue of JAMA.

Released: 26-Aug-2010 5:00 PM EDT
People Over 80 Often Have Mixed Pathologies in Their Brains That Account for Their Memory Loss, Confusion
LifeBridge Health

Most recent studies show that elderly people over the age of 80 often have mixed pathologies in their brains that account for their memory loss and confusion. Very few senior citizens have “pure Alzheimer disease”; therefore, this terminology should be used with caution. It now appears that vascular problems such as high blood pressure and diabetes can shrink the parts of the brain that control memory and can significantly affect at what age elderly people become demented. The following tips may be able to postpone cognitive decline late in life.

17-Aug-2010 2:20 PM EDT
Insulin Resistance, Type 2 Diabetes Linked to Plaques Associated with Alzheimer’s Disease
American Academy of Neurology (AAN)

People with insulin resistance and type 2 diabetes appear to be at an increased risk of developing plaques in the brain that are associated with Alzheimer’s disease, according to new research published in the August 25, 2010, issue of Neurology®, the medical journal of the American Academy of Neurology.

Released: 18-Aug-2010 2:00 PM EDT
Study Explains Why Alzheimer’s Drug is Both Safe and Effective
Sanford Burnham Prebys

Sanford-Burnham scientists uncover new clues to the molecular action of memantine, a drug used to treat Alzheimer’s disease, that show why side effects are rare.

Released: 17-Aug-2010 1:20 PM EDT
B Vitamins and the Aging Brain Examined
USDA, Office of Research, Education, and Economics

A U.S. Department of Agriculture nutritionist has collaborated in ongoing research that has taken a closer look at the role the B vitamins may play in preventing decline in brain function.

Released: 4-Aug-2010 12:10 PM EDT
Deep Brain Stimulation Shows Promise for Patients with Alzheimer’s
University Health Network (UHN)

In a world first, Dr. Andres M. Lozano and his team at Toronto Western Hospital has shown using Deep Brain Stimulation (DBS) on patients with early signs of Alzheimer’s disease is safe and may help improve memory.

Released: 29-Jul-2010 12:20 PM EDT
New Pathway to Parkinson’s and Alzheimer’s Diseases
Sanford Burnham Prebys

Sanford-Burnham researchers uncover new clues about the cause of brain cell death in neurodegenerative disorders such as Parkinson’s, Alzheimer’s, and Huntington’s diseases

20-Jul-2010 1:40 PM EDT
Sleep Disorder May Signal Dementia, Parkinson’s Disease Up to 50 Years Early
American Academy of Neurology (AAN)

A new study shows that a sleep disorder may be a sign of dementia or Parkinson’s disease up to 50 years before the disorders are diagnosed. The research is published in the July 28, 2010, online issue of Neurology®, the medical journal of the American Academy of Neurology.

23-Jul-2010 4:30 PM EDT
Delirium in Older Patients Associated with Greater Risk of Death, Dementia and Institutionalization
JAMA - Journal of the American Medical Association

A review and analysis of previous research indicates that delirium in elderly patients is associated with an increased risk of death, dementia, and institutionalization, independent of age, co-existing illnesses or illness severity, according to a study in the July 28 issue of JAMA.

Released: 22-Jul-2010 2:25 PM EDT
SIRT1 Gene Important for Memory
University of Southern California (USC)

Much-studied protein involved in aging, and tied to red wine ingredient resveratrol, is required for recall in mice; but over-expression fails to improve performance, according to a new study in Journal of Neuroscience.

   
Released: 22-Jul-2010 1:30 PM EDT
SBU Neurobiology and Behavior Chair Wins Nih Award to Conduct Research on Optogenetic Stimulation of Cholinergic Circuits in the Brain
Stony Brook University

Lorna W. Role, Ph.D. to receive up to $2.5 million over five years for research that could help individuals with Alzheimer's and other degenerative brain diseases.

Released: 15-Jul-2010 4:00 PM EDT
Rescuing Fruit Flies from Alzheimer’s Disease
Perelman School of Medicine at the University of Pennsylvania

Investigators have found that fruit fly males -- in which the activity of an Alzheimer’s disease protein is reduced by 50 percent -- show impairments in learning and memory as they age. What’s more, the researchers were able to prevent the age-related deficits by treating the flies with drugs such as lithium, or by genetic manipulations that reduced nerve-cell signaling.

12-Jul-2010 4:00 PM EDT
Researchers Find Dementia in Diabetics Differs from Dementia in Nondiabetics
Mayo Clinic

Researchers from Mayo Clinic’s Florida campus say that dementia in some diabetics appears to be caused often by vascular disease in the brain, and the dementia that develops in people without diabetes is more likely associated with deposition of the plaque seen in people with Alzheimer’s disease.

Released: 14-Jul-2010 2:20 PM EDT
Major Alzheimer’s Risk Gene Causes Alterations in Shapes of Brain Protein Deposits
Mount Sinai Health System

Researchers at Mount Sinai School of Medicine have used a newly discovered class of biomarkers to investigate the possibility that the shape of brain protein deposits is different in people with Alzheimer’s who have the highest-risk gene type than in those with the condition who have a neutral risk gene type. The study is being presented July 14 at the 2010 Alzheimer’s Association International Conference on Alzheimer's Disease in Honolulu, Hawaii.



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