Medulloblastoma, the most commonly occurring malignant brain tumor in children, can be classified into four subgroups—each with a different risk profile requiring subgroup-specific therapy. Currently, subgroup determination is done after surgical removal of the tumor.
Cedars-Sinai researchers have identified a novel genetic biomarker responsible for the progression of many breast and prostate cancers. The finding could bolster efforts to better identify patients who respond to certain types of chemotherapy drugs.
The 2015 International Annual Meeting of the Human Factors and Ergonomics Society features more than 400 presentations from leading HF/E experts across multiple domains on topics including patient safety, product design, driver distraction, emergency response, human-robot interaction, and more.
Pasadena Magazine’s annual Top Doctors issue has recognized 85 physicians with privileges to practice at Children's Hospital Los Angeles. Many of the honorees are members of the Children's Hospital Los Angeles Medical Group and are academically affiliated with the Keck School of Medicine of the University of Southern California.
High-grade serous ovarian cancer often responds well to the chemotherapy drug carboplatin, but why it so frequently comes back after treatment has been a medical mystery. Now a team of UCLA researchers has discovered that a subset of tumor cells that don’t produce the protein CA125, a biomarker used to test for ovarian cancer, has an enhanced ability to repair their DNA and resist programmed cell death — which allows the cells to evade the drug and live long enough to regrow the original tumor.
The California Wellness Foundation’s (Cal Wellness) Board of Directors elected a new member, USC Annenberg Dean Ernest J. Wilson III
A wealth of programs target autistic kids. But what about when they grow up? UCLA's Program for the Education and Enrichment of Relational Skills is the only evidence-based approach to teaching social skills to young adults with autism.
Robert Hernandez, associate professor of professional practice at USC Annenberg, has been chosen by the national Society of Professional Journalists to receive its Distinguished Teaching in Journalism Award.
Cedars-Sinai's July tip sheet includes story ideas about gene editing, a summer stem cell program for high school students, sudden cardiac arrest in African-Americans, and a "wrist watch" type device that is helping to track the movements of Parkinson's disease patients.
The UCLA department of neurosurgery ranks No. 2 in the nation in scholarly research, according to a recent paper evaluating the impact of published articles in the field.
A study by the Los Angeles County Trauma Consortium has found that compliance with Brain Trauma Foundation guidelines for treating traumatic brain injury do not necessarily lead to lower mortality rates.
For the first time, UCLA researchers have shown that a natural protein fragment produced in the brain can act as an inhibitor of a key enzyme implicated in the onset of Alzheimer’s disease, a finding that could lead to the development of new drugs to treat the disease.
A new study published in the Journal of Cognitive Engineering and Decision Making aims to evaluate the types of search strategies that Internet users adopt when trying to solve a complicated health problem.
Researchers at Children’s Hospital Los Angeles and The Saban Research Institute of CHLA created a dynamic functional mouse model for lung injury repair, a tool that will help scientists explain the origins of lung disease and provide a system by which new therapies can be identified and tested.
Findings are the first to shed light on the genetic differences between DiGeorge syndrome patients with autism and those with psychosis.
Looking at measurements of the vertebrae – the series of small bones that make up the spinal column – in newborn children, investigators at Children’s Hospital Los Angeles found that differences between the sexes are present at birth.
UCLA Health and One Legacy honor organ, eye and tissue donors
UCLA scientists have discovered a groundbreaking experimental therapy that has the ability to suppress the development of ulcerative colitis (UC), a disease which causes inflammation in the digestive tract and colon cancer. The treatment utilizes a chemical inhibitor able to block an RNA molecule (microRNA-214) involved in the transmission of genetic information.
Researchers in the Division of Hematology, Oncology and Blood & Marrow Transplantation at CHLA have shown greatly improved outcomes in using stem cell transplantation to treat patients with a serious but very rare form of chronic blood cancer called juvenile myelomonocytic leukemia (JMML).
An assessment tool developed jointly by psychiatrists at UCLA and the University of Texas, Houston will be the first to help identify maladaptive grief in youth between 8 and 18.
For the first time, researchers have employed a gene-editing technique involving low-dose irradiation to repair patient cells, according to a study published in the journal Stem Cells Translational Medicine. This method, developed by researchers in the Cedars-Sinai Board of Governors Regenerative Medicine Institute, is 10 times more effective than techniques currently in use.
UCLA’s Jonsson Comprehensive Cancer Center is ranked among the top 10 cancer centers in the nation, according to a U.S. News & World Report survey of board-certified physicians from across the country. The survey reviewed patient outcomes, the cancer center’s reputation among physicians, mortality rates and other care-related factors.
UCLA Health’s hospitals have been named to U.S. News and World Report’s 2015-2016 Best Hospitals Honor Roll. UCLA, which previously ranked No. 5 in the country, tied for No. 3 this year.
Johanna Olson, MD, and her colleagues at Children’s Hospital Los Angeles, provide care for the largest number of transyouth in the U.S. and have enrolled 101 patients in a study to determine the safety and efficacy of treatment that helps patients bring their bodies into closer alignment with their gender of identity.
Compared to Caucasians, African-Americans face twice the rate of sudden cardiac arrest, according to a new study from the Cedars-Sinai Heart Institute.
•UCLA scientists have for the first time demonstrated the importance of sodium-dependent glucose transporters (SGLTs) in delivering glucose to pancreatic and prostate cancer cells •Study results show promising evidence that current SGLT inhibitor drugs (such as those commonly used to treat diabetes) could potentially be used to block glucose uptake and reduce tumor growth in these cancers •Researchers also utilized PET imaging to measure SGLT activity, suggesting the technology could be used to better diagnose pancreatic and prostate cancers •Pancreatic and prostate cancers are among the most deadly forms of cancer in men, and new therapies are urgently needed to combat these diseases
Twenty-one Los Angeles high school students will be at Cedars-Sinai the week of July 20 to participate in hands-on stem cell research and to get a jump-start on potential careers in scientific research. The students will be participating in the fourth annual Research Week program at the Cedars-Sinai Board of Governors Regenerative Medicine Institute.
Cedars-Sinai's July tip sheet includes story ideas related to Alzheimer's disease research, an upcoming conference on Lou Gehrig's Disease, also known as ALS, identification of critical genes responsible for brain tumor growth, and an online registry that is improving clinical research study participation. To pursue any of these story ideas, please contact the respective individuals listed.
Why do some youngsters bounce back quickly from a traumatic brain injury, while others suffer for years? New UCLA/USC research suggests that damage to the coating around the brain’s nerve fibers--not injury severity-- may explain the difference.
USC Annenberg today announced that Monica Castillo has been selected as the school’s first Sony Pictures Entertainment Fellow.
A physical education program that brings commercial-grade fitness equipment to under-resourced schools, along with a curriculum based on boosting confidence and making participation more enjoyable, dramatically increases students’ performance on California’s standardized physical fitness test, a UCLA study has found.
Recent research has warned of the health detriments associated with sitting for long stretches of time at the office, but what about the nearly half of all employees worldwide who are required to stand for more than 75% of their workdays?
Research for Her™, Cedars-Sinai’s groundbreaking online registry that matches women with research studies and clinical trials, enrolled study participants more quickly when compared with traditional paper-based registries, according to new research published in the journal Gynecologic Oncology.
After generating new brain tumor models, Cedars-Sinai scientists in the Board of Governors Regenerative Medicine Institute identified the role of a family of genes underlying tumor growth in a wide spectrum of high grade brain tumors.
The Board of Trustees at Children’s Hospital Los Angeles (CHLA) has announced that Paul S. Viviano, currently the chief executive officer for the University of California, San Diego Health System and associate vice chancellor for UC San Diego Health Sciences, will serve as the organization’s new president and chief executive officer beginning Aug. 24, 2015. Viviano will be a member of the hospital’s Board of Trustees and will succeed Richard D. Cordova, FACHE, who previously announced his approaching retirement last December.
Though the ACA created several national initiatives to reduce hospital readmissions for heart attacks and congestive heart failure, there is nothing for sepsis, a potentially life-threatening illness caused by infection. Yet it costs the health care system more than both combined.
Physicians in the newly launched Diabetes & Metabolism Research Institute at City of Hope are now providing islet cell transplantation to suitable candidates through a clinical trial that they believe will be the first step in a multipronged effort to permanently cure type 1 diabetes.
Cedars-Sinai researchers have successfully tested two new methods for preserving cognition in laboratory mice that exhibit features of Alzheimer’s disease by using white blood cells from bone marrow and a drug for multiple sclerosis to control immune response in the brain.
Already pioneers in the use of immunotherapy, City of Hope researchers are now testing the bold approach to cancer treatment against one of medicine’s biggest challenges: brain cancer. This month, they will launch a clinical trial using patients’ own modified T cells to fight advanced brain tumors.
Monitoring men with very low- and low-risk prostate cancers using watchful waiting or active surveillance, called expectant management, is a useful approach for a large number of men with localized tumors and could spare them the debilitating side effects of aggressive treatments that are too often unnecessarily used in this patient population, a UCLA review of common practices in prostate cancer has found.
Beginning today, CHLA’s renowned specialists will staff Providence Tarzana’s Pediatrics Department inpatient unit as well as its pediatric and neonatal intensive care units – known as the PICU and NICU. Staff will be available 24 hours a day, allowing families access to high-quality specialty care for their children, closer to home.
A 44-year-old woman has received a successful heart transplant at Ronald Reagan UCLA Medical Center, thanks to an experimental Total Artificial Heart designed for smaller patients. The UCLA patient is the first person in California to receive the smaller Total Artificial Heart, and the first patient in the world with the device to be bridged to a successful heart transplant.
In the first study of its kind, UCLA and United Kingdom researchers found that neurons in a specific brain region play a key role in rapidly forming memories about every day events, a finding that may result in a better understanding of memory loss and new methods to fight it in Alzheimer’s and other neurological diseases.
UCLA doctors used a 3-D model of a patient’s heart to guide a tricky minimally-invasive valve replacement. UCLA patient Richard Whitaker was not a candidate for traditional surgery due his heart's unique anatomy and previous surgeries. Doctors practiced with the 3-D heart model before the actual procedure to make sure the valve would fit, which it did! Richard is now back to work after having the procedure and looking forward to planning a trip to Europe.
Michael Allen Pulsipher, MD, will join the Children’s Center for Cancer and Blood Diseases and the Division of Hematology, Oncology and Blood and Marrow Transplantation at Children’s Hospital Los Angeles as head of the Section of Blood and Marrow Transplantation (BMT) and as BMT clinical research chair, effective July 1, 2015. In addition, Pulsipher will be a professor of Pediatrics at the Keck School of Medicine of the University of Southern California (USC) and a Member of the USC Norris Comprehensive Cancer Center.
A team of neonatologists at Children’s Hospital Los Angeles investigated the use of robot-assisted telemedicine in performing bedside rounds and directing daily care for infants with mild-to-moderate disease. This is the first published report of using telemedicine for patient rounds in a neonatal intensive care unit (NICU).
Lynda Boone Fetter and Arnold “Arnie” Kleiner have been elected co-chairs of the Board of Trustees of Children’s Hospital Los Angeles, succeeding outgoing Board Co-chairs Cathy Siegel Weiss and Ted Samuels.
A new study by UCLA scientists has found that women diagnosed with breast cancer and treated with a one-week regimen of partial breast radiation after the surgical removal of the tumor, or lumpectomy, saw no increase in cancer recurrence or difference in cosmetic outcomes compared to women who received radiation of the entire breast for a period of up to six weeks after surgery. The study is one of the largest ever done on partial breast irradiation.
Chronic disease and mental health issues disproportionately affect low-income African-Americans, Latinos and Hispanics. Researchers at UCLA have developed a screening tool that may provide better treatment.
New research offers further evidence that cocaine use disrupts the immune system, making people who use it more likely to become infected with HIV.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right