A new study by UCLA scientists shows that enhancers, snippets of DNA that contribute to gene regulation, fall into the same “insulated neighborhoods” or chromatin loops as the target gene and other gene-specific regulatory elements.
Here's a great holiday story about a 20-year-old Reno, NV, man whose mother saved his life. Harley Brackney's snowboarding accident and subsequent trip to the emergency room led to the shocking discovery that he had a life-altering condition - stage 5 renal failure - and needed a kidney transplant. Fortunately for Harley Brackney, his mom was a perfect match and instead of waiting 7 to 10 years for a donor organ -- as many people must -- he was able to have a transplant in just a matter of months.
Two studies have linked DNA changes to their molecular effects in the brain, revealing new mechanisms for psychiatric diseases. The findings provide a roadmap for developing a new generation of therapies for conditions like autism, schizophrenia and bipolar disorder.
By age 12 to 18 months, 6.25% of children exposed to Zika during their mothers’ pregnancies had eye abnormalities, 12.2% had hearing problems, and 11.7% had severe delays in language, motor skills and/or cognitive function. In all, 14.5% had at least one of the three abnormalities.
Conventional math cannot adequately model the interaction of multiple genes over multiple time frames – a necessary foundation for any cancer-fighting drugs. The study, published in “Frontiers in Physiology” by Mahboobeh Ghorbani, Edmond Jonckheere and Paul Bogdan of the Ming Hsieh Department of Electrical Engineering, is the first study that accounts for the memory, cross-dependence and fractality of gene expression
Many people who are diagnosed with cancer will undergo some type of surgery to treat their disease — almost 95 percent of people with early-diagnosed breast cancer will require surgery and it’s often the first line of treatment for people with brain tumors, for example. But despite improvements in surgical techniques over the past decade, the cancer often comes back after the procedure.
Few governments make pre-primary education available on a tuition-free basis for two or more years, according to a new study from the WORLD Policy Analysis Center.
Of the 165,000 men in the U.S. expected to be diagnosed with prostate cancer this year, about half will have low-risk disease. Many of those patients will opt for active surveillance -- a process in which men with low-risk, slow-growing prostate cancer are regularly monitored to see if the cancer starts to grow and requires treatment.
Providing supervised access to medical-grade heroin to people whose use continues after trying multiple traditional treatments has been successful in other countries, and should be piloted and studied in the United States, according to a new RAND Corporation study.
Vascular surgeon Ali Azizzadeh, MD, was the first to use a newly approved, minimally invasive device to perform a series of innovative surgeries on patients with aneurysms of the aorta, the main vessel that delivers blood from the heart to the rest of the body.
New research from Cedars-Sinai has identified neurons that play a role in how people recognize errors they make, a discovery that may have implications for the treatment of conditions including obsessive-compulsive disorder and schizophrenia.
A UCLA-led research team has identified genetic processes involved in the neurodegeneration that occurs in dementia — an important step on the path toward developing therapies that could slow or halt the course of the disease. The findings appear Dec. 3 in the journal Nature Medicine.
For the first time, a 360-degree virtual reality (VR) Continuing Medical Education (CME) accredited course in GI surgery is available for streaming to surgeons and medical professionals. The course is a collaboration between medical experts at Cedars-Sinai and GIBLIB, the streaming media platform offering the largest library of on-demand medical lectures and surgical videos in the newest formats.
Usually one would have to visit an art museum in order to see the beautiful landscapes by Vietnamese-American artist, Christine Nguyen, but drivers in West Hollywood get an up-close view of her oversized artwork as part of their daily commute. Nguyen's art is displayed on protective fencing surrounding construction at the future home of the Cedars-Sinai Saul & Joyce Brandman Breast Center.
Opioid use in Mexico has been low, but national and international factors are converging and a threat of increased drug and addiction rates exists. Many of these factors may have originated in the U.S., making this a potential joint U.S.-Mexico epidemic.
UCLA researchers have found that commonly used hormone therapies for women diagnosed with breast cancer do not appear to cause significant cognitive dysfunction following the treatment.
With many prospective students, their families and communities facing hardship due to wildfires affecting the entire state, the California State University (CSU) is extending the priority application deadline for fall 2019 admission to December 15.
A new study has identified a novel molecular driver of lethal prostate cancer, along with a molecule that could be used to attack it. The findings were made in laboratory mice. If confirmed in humans, they could lead to more effective ways to control certain aggressive types of prostate cancer, the second-leading cause of cancer death for men in the U.S.
Heitham Hassoun, MD, a leading international health expert, has been named vice president and medical director of Cedars-Sinai's Center for International Health. Hassoun joins Cedars-Sinai from Johns Hopkins Medicine, where he was medical director for Global Healthcare at Johns Hopkins Medicine International.
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