Engaging in repetitive and ritualistic behaviors is part of typical child development. However, behaviors that develop into obsessive and compulsive symptoms (OCS) may represent a red flag for serious psychiatric conditions.
A molecule derived from a type of primrose could prove to be a potent inhibitor of metastatic growth for a rare and aggressive cancer.
Until now, it was unclear how this DNA packing affected development in early embryos. In a paper published this week in Science, researchers from the Perelman School of Medicine at the University of Pennsylvania found that in mouse embryos--only eight days after fertilization--compacted regions along the genome increase at protein-coding genes. Days later in the cell differentiation phase, these domains open to allow certain genes to be read and made into their corresponding proteins.
When researchers unlock the mysteries of Castleman disease, they may single out 2018 as one of the years in which they laid the foundation to help them turn the key, and the University of Pennsylvania has been the epicenter.
An implantable neuroprosthetic device may one day provide a new approach to restoring more natural facial movement in patients with one-sided facial paralysis (hemifacial palsy), suggests a study in the January issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
A growing body of evidence supports the effectiveness of botulinum toxin injections in reducing the frequency of chronic migraine headaches, concludes an updated review and analysis in the January issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
An analysis of nationwide data shows patients with symptoms are most likely to return to the hospital within a week of their thyroid surgery, suggesting avenues for better care.
Researchers at Children’s Hospital of Philadelphia (CHOP) evaluated a digital medicine tool designed as an investigational treatment for children with autism spectrum disorder (ASD) and co-occurring attention/deficit-hyperactivity disorder (ADHD).
Scientists have used a combination of mathematical modeling, electrophysiology, and computer simulations to explain how cells communicate effectively in highly constricted spaces such as the olfactory cilia. The findings will inform future studies of cellular signaling in the olfactory system and other confined spaces of the nervous system.
Wolters Kluwer, Health and the American Journal of Nursing (AJN) announced the 2018 winners of its annual AJN Book of the Year Awards honoring exceptional texts for advancing healthcare quality. The list of winners appears in the January 2019 issue of AJN, the “leading voice of nursing since 1900.” AJN is published in the Lippincott portfolio by Wolters Kluwer.
At least for brief periods, overlapping surgery is safe for patients undergoing outpatient or "same-day" orthopaedic surgery procedures, reports a study in the December 19, 2018 issue of The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.
A community-based, pilot study shows a high-tech app is as effective as low-tech picture card intervention at improving social and communication skills in children with autism.
The Monell Center and Thomas Jefferson University announce the funding of five collaborative pilot grants for projects that combine Monell’s research on the senses of taste and smell with Jefferson’s complementary strengths in the basic and clinical neurosciences.
Findings published in JNCCN-Journal of the National Comprehensive Cancer Network examine the differences between patient- and clinician-reported outcomes; recommend a greater focus on the cumulative effect of multiple low-level toxicities.
Brain tumor patients will now have access to Penn Medicine’s world-renowned cancer expertise through the launch of a new telemedicine second opinion program for brain tumors.
The overwhelming draw of DTC genetic kits is their appeal to discover more about one’s ancestry and heritage, as well as health and wellness. When I first wrote on this topic, I sought details about my risk for heart disease, given my family history, but as I learned from speaking with several Penn Medicine geneticists, DTC kits aren’t set up for this area yet. However, it is possible to glean the genetic basis for seemingly off-beat behaviors and traits, such as toe-length ratio or sweet-versus-salty taste preference.
Researcher shows the two most common means of resistance to BRAF and MEK inhibitors are actually connected processes and can be targeted by other therapies.
A new treatment for patients with a form of congenital retinal blindness has shown success in improving vision, according to results published today in led by researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania.
A new study from the University of Pennsylvania School of Nursing’s Center for Health Outcomes and Policy Research (CHOPR) describes the quality of end of life care in nearly 500 U.S. hospitals, utilizing nearly 13,000 bedside nurses as informants of quality. The study has been published online first. It will also be in a future issue of the Journal of the American Geriatrics Society.
Researchers find an effective way to treat an underdiagnosed condition that can cause heart attack and heart-attack-like symptoms.
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