Research Alert
Article title: Lung immune tone via gut-lung axis: gut-derived LPS and short-chain fatty acids' immunometabolic regulation of lung IL-1β, FFAR2 and FFAR3 expression
Authors: Qing Liu, Xiaoli Tian, Daisuke Maruyama, Mehrdad Arjomandi, Arun Prakash
From the authors: “Together, this translational study using mouse and human lung tissue and cells point to an important role for the gut microbiome and their [short-chain fatty acids] in establishing and regulating lung immune tone.”
This study is highlighted as one of June’s “best of the best” as part of the American Physiological Society's APSselect program.
Journal Link: American Journal of Physiology-Lung Cellular and Molecular Physiology