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Immunology

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Medicine

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Cancer, Radiotherapy, Immune Response

Ludwig Researchers Unravel Novel Mechanism by Which Tumors Grow Resistant to Radiotherapy

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A Ludwig Cancer Research study has uncovered a key mechanism by which tumors develop resistance to radiation therapy and shown how such resistance might be overcome with drugs that are currently under development.

Medicine

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Cancer, Immunotherapy, Immunology, Immune System, Side Effects, cancer guidelines

Society for Immunotherapy of Cancer Spearheads Initiative to Align Management of Immunotherapy Side Effects

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The first consensus recommendations on recognition and clinical management of immune-related side effects from cancer immunotherapy are published today in the Journal for ImmunoTherapy of Cancer (JITC).

Science

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CRISPR, CRISPR-Cas9, Gene Editing, infectious disease control, DNA and CRISPR, RNA, Darpa

Infectious diseases: CTRL + ALT + Delete

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Gene editing holds great promise for ‘deleting’ diseases from human bodies. Sandia National Laboratories is now working to make this technology safer and to ensure that one day it can be delivered into humans without triggering adverse immune system reactions or causing other undesirable side effects.

Medicine

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CAR T-cell therapy, Leukemia & Lymphoma Society, Acute Lymphoblastic Leukemia (ALL

The Leukemia & Lymphoma Society Awards Grant to Savoldo for Immunotherapy Research

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A grant from The Leukemia & Lymphoma Society will help fund clinical research led by UNC Lineberger's Barbara Savoldo, MD, PhD, into an investigational chimeric antigen receptor (CAR) T-cell treatment for acute lymphoblastic leukemia that would include a built-in "safety switch."

Medicine

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Allergies, Allergy, Fall allergies

Don’t Let Fall Allergies Leave You in the Cold

Fall allergies have symptoms similar to the flu, but treatment varies drastically.

Medicine

Science

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Alzheimber's Disease, Alzheimer, Alzheimer Disease & Associated Disorders, Gut Bacteria, Rutgers, Rutgers Univeristy , Disease Progression

Age and Gut Bacteria Contribute to MS Disease Progression, According to Rutgers Study

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https://www.ncbi.nlm.nih.gov/pubmed/29078267

Medicine

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Preemies Activism, Craniofacial Conditions, New Therapy Lessons, and More in the Children's Health News Source

Click here for the latest research and features on Children's Health.

Medicine

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Cancer, Immunotherapy, Cancer Immunity

How a Poorly Explored Immune Cell May Impact Cancer Immunity and Immunotherapy

The immune cells that are trained to fight off the body’s invaders can become defective. It’s what allows cancer to develop. So most research has targeted these co-called effector T-cells. But a new study takes a step back and considers: What if the problem isn’t with the effector T-cells but starts higher up the cellular chain?

Medicine

Science

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Cryo Electron Microscopy, cryo-EM, Immune activation

Detailed View of Immune Proteins Could Lead to New Pathogen-Defense Strategies

Biologists at Berkeley Lab and UC Berkeley used cryo-EM to resolve the structure of a ring of proteins used by the immune system to summon support when under attack, providing new insight into potential strategies for protection from pathogens. The researchers captured the high-resolution image of a protein ring, called an inflammasome, as it was bound to flagellin, a protein from the whiplike tail used by bacteria to propel themselves forward.

Medicine

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cryo-EM, Cryo Electron Microscopy, Immune System, Pathogen detection

How the Immune System Identifies Invading Bacteria

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Never-before-seen images of mouse immune system proteins and bacterial bits reveal an inspection strategy that identifies pathogens.







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