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A protein that helps colorectal cancer cells spread to other parts of the body could be an effective treatment target.

Channels: All Journal News, Cancer, Genetics, Immunology,

Keywords: Cancer, Biology, Genetics, Immunology, Molecular Biology, Medicine, Health

John Theurer Cancer Center at Hackensack University Medical Center is the only site in New Jersey and one of just 17 in the country participating in a multicenter international Phase II study of an innovative personalized cancer vaccine being evaluated in combination with pembrolizumab immunotherapy in patients with melanoma that has been surgically removed but has a high risk of coming back. The hope is that the vaccine can prime a patient's immune system to be more responsive to immunotherapy and reduce the risk of cancer recurrence.

Channels: Cancer, Clinical Trials, Immunology, Personalized Medicine, Vaccines, Surgery, social media distr - auto for marked clients,

Research into engineering artificial organs that mimic the functions of human lymph nodes at The University of Alabama in Huntsville (UAH) has garnered one of its professors a $507,777 National Science Foundation (NSF) Faculty Early Career Development Program (CAREER) Award.

Channels: Cancer, Cell Biology, Immunology, Embargoed Feed - hidden, Grant Funded News,

Keywords: immunoengineering, artificial glands, Immunotheapy, Cancer, Lymph Gland, B-cell, UAH, University of Alabama in Huntsville, hudsonalpha institute for biotechnology, National Science Foundation (NSF) , NSF, Nsf Career Award, Bioengineering

The continuing epidemic of pre-term birth includes this stark reality: tiny, fragile babies are born with underdeveloped lungs and prone to lifelong respiratory infections and related chronic illnesses. Cincinnati Children’s researchers report in Immunology the discovery of a complex biological process could in the development of cost effective treatments to help babies develop lifelong pulmonary resistance to respiratory infections.

Channels: Cell Biology, Children's Health, Infectious Diseases, Respiratory Diseases and Disorders, Immunology, Embargoed Feed - hidden, All Journal News,

Keywords: Premature Birth, Babies, pulmonary infections, Pneumonia, Lung Infections, Pediatrics, Cell Press , Immunity, Cincinnati Children's Hospital Medical Center, news release, news

A Ludwig Cancer Research study has identified a mechanism by which regulatory T cells, which suppress immune responses, adapt their metabolism to thrive in the harsh microenvironment of the tumor.

Channels: All Journal News, Cancer, Immunology, National Institutes of Health (NIH), Nature (journal), Cancer Center Featured Story 2,

Keywords: Cancer, immunotheraphy, cancerresearch

Yvonne Chen engineers immune cells to target their most evasive enemy: cancer. New cancer immunotherapies generate immune cells that are effective killers of blood cancers, but they have a hard time with solid tumors.

Channels: Medical Meetings, All Journal News, Blood, Cancer, Immunology, Embargoed Feed - hidden,

Keywords: Biophysical Society Annual Meeting, UCLA, UCLA Engineering, Cancer, Immunotherapy, Tumors, BPS20, University Of California Los Angeles, BPS, Biophysical Society 64th Annual Meeting, Yvonne Y Chen, t-cells, chimeric antigen receptor, cars, CAR-T, jonsson comprehensive cancer center

The insights from the PEXIVAS Trial, a 10-year study, shows treatment for ANCA-associated vasculitis can become much more patient-friendly by using half the typical dose of steroids and no blood plasma exchanges

Channels: All Journal News, Healthcare, Immunology, Kidney Disease, National Institutes of Health (NIH), NEJM, Embargoed Feed - hidden, Grant Funded News,

Keywords: Perelman School of Medicine at the University of Pennsylvania, Rheumatology, Vasculitis, McMaster University, University Of Cambridge

It's no coincidence that some of the worst viral disease outbreaks in recent years -- SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus -- originated in bats.

Channels: All Journal News, Cell Biology, Environmental Science, Immunology, Infectious Diseases, Public Health, Ebola, China News, Southeast Asia News, Coronavirus,

Keywords: Cell Biology, Disease In The Developing World, Ecology/Environment, Infectious/Emerging Diseases, Parasitology, Virology, Zoology, veterinary science

Columbia Engineers have engineered probiotics to safely deliver immunotherapies within tumors, including nanobodies against two proven therapeutic targets—PD-L1 and CTLA-4. Continuously released by bacteria, the drugs continue to attack the tumor after just one dose, facilitating an immune response resulting in tumor regression. The versatile probiotic platform can also be used to deliver multiple immunotherapies simultaneously, enabling the release of effective therapeutic combinations within the tumor for more difficult-to-treat cancers like colorectal cancer.

Channels: All Journal News, Cancer, Immunology, Pharmaceuticals, National Institutes of Health (NIH), Embargoed Feed - hidden,

Keywords: Cancer, Immunotheapy, Probiotic, Tumor, Checkpoint Inhibition, Bacteria, Antibodies