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Article ID: 702172

Researchers from Australia and Japan have discovered a new human immunodeficiency syndrome in two patients on separate continents. The study, which will be published October 18 in the Journal of Experimental Medicine, reveals that a mutation in a gene called IKBKB disrupts the immune system, leading to excessive inflammation and the loss of both T and B white blood cells.

Article ID: 702338

UT Southwestern biochemist Dr. Zhijian “James” Chen today was named winner of the prestigious 2019 Breakthrough Prize in Life Sciences for his discovery of the cGAS enzyme that launches the body’s immune defense against infections and cancers. That enzyme patrols the cell’s interior and triggers the immune system in response to DNA.

Article ID: 701981

Robust environmental monitoring should be used as the world approaches global eradication of polio, say University of Michigan researchers who recently studied the epidemiology of the 2013 silent polio outbreak in Rahat, Israel.

Article ID: 701899

The American Association of Pharmaceutical Scientists (AAPS) is pleased to announce the elevation of six recipients to AAPS Fellow (FAAPS), one of the highest honors given to members of the association. Each year

Article ID: 702165

Wistar researchers have characterized the function of neutrophils, a type of white blood cells, during early stages of tumor progression, showing that they migrate from the bone marrow to distant sites and facilitate tumor cell seeding and establishment of metastasis.

Article ID: 702143

The steps cells take in response to challenges are more complex than previously thought, finds new research. The study investigates a system relevant to cancer, viral infection, and diabetes.

Article ID: 702115

Tamara Strauss has been living with high-grade, stage IV pancreatic neuroendocrine cancer for more than three years. Current treatments, although effective for her, are highly toxic. Tamara enrolled in a first-of-its-kind, pilot study at Moores Cancer Center at UC San Diego Health to test a personalized vaccine using her unique cancer mutations to boost an anti-tumor immune response.

Article ID: 702086

Researchers are investigating whether infants born into poverty have stronger inflammatory responses, predisposing them to chronic disease during their lives.