Latest News from: UC Davis MIND Institute

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Released: 28-May-2020 1:35 PM EDT
Autism severity can change substantially during early childhood
UC Davis MIND Institute

A UC Davis MIND Institute study found that around 30% of young children with autism have less severe autism symptoms at age 6 than they did at age 3, with some losing their autism diagnoses entirely. It also found that girls tend to show greater reduction and less rise in their autism symptom severity than boys with autism. Children with higher IQs were more likely to show a reduction in their symptoms.

Newswise: Depression symptoms linked to reduced cognitive control in people with autism
Released: 19-May-2020 3:35 PM EDT
Depression symptoms linked to reduced cognitive control in people with autism
UC Davis MIND Institute

Adolescents and young adults with autism spectrum disorder (ASD) and those with typical development show similar proactive cognitive control. However, symptoms of depression in individuals with autism were linked to less proactive control, a UC Davis study found.

Newswise: Helping the world understand, detect and treat a devasting genetic disorder
Released: 23-Jan-2020 1:55 PM EST
Helping the world understand, detect and treat a devasting genetic disorder
UC Davis MIND Institute

Fragile X syndrome is a debilitating genetic neurodevelopmental disorder that affects people worldwide, but many doctors don’t know anything about it, let alone have the resources to properly diagnose or treat it.

Newswise:Video Embedded healing-and-hope-treating-fragile-x-in-serbia
VIDEO
Released: 23-Jan-2020 1:20 PM EST
Healing and Hope: Treating Fragile X in Serbia
UC Davis MIND Institute

Doctors and scientists — experts in the rare and severely disabling fragile X syndrome — had arrived from the United States, including six from the UC Davis MIND Institute. They came to offer the families useful information and maybe open doors to desperately needed help in a region of the world that, until fairly recently, hardly recognized fragile X syndrome, let alone knew how to diagnose or treat it.

Newswise: Enlarged amygdala involved in psychiatric challenges in young girls with autism
Released: 21-Jan-2020 2:55 PM EST
Enlarged amygdala involved in psychiatric challenges in young girls with autism
UC Davis MIND Institute

behavioral problems than similar age boys with ASD. These challenges are associated with a larger amygdala, a UC Davis Health study has found. The amygdala is a key part of the brain that helps regulate emotions and detects threats.

Newswise: Computer-based memory games may benefit people with fragile X syndrome
Released: 15-Apr-2019 6:05 PM EDT
Computer-based memory games may benefit people with fragile X syndrome
UC Davis MIND Institute

Memory training game may help people with fragile X and other intellectual disorders.

Newswise: Experimental Drug Improves Eye Gaze Behavior in Fragile X Syndrome
15-Jan-2019 6:05 PM EST
Experimental Drug Improves Eye Gaze Behavior in Fragile X Syndrome
UC Davis MIND Institute

Researchers at MIND Institute at UC Davis and Rush University Medical Center have found that mavoglurant, an experimental drug known as an mGluR5 negative modulator, can positively modify a key characteristic behavior in individuals with fragile X syndrome (FXS).

Newswise: Siblings of children with autism or ADHD are at elevated risk for both disorders
6-Dec-2018 3:00 PM EST
Siblings of children with autism or ADHD are at elevated risk for both disorders
UC Davis MIND Institute

Later-born siblings of children with autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD) are at elevated risk for both disorders, a new study led by Meghan Miller, assistant professor in the Department of Psychiatry and Behavioral Sciences and at the UC Davis MIND Institute, has concluded. The findings appear today in JAMA Pediatrics.

Newswise: Third Study Confirms: Increased Cerebrospinal Fluid Can Predict Autism
26-Sep-2018 6:00 PM EDT
Third Study Confirms: Increased Cerebrospinal Fluid Can Predict Autism
UC Davis MIND Institute

Researchers at the UC Davis MIND Institute and the University of North Carolina have shown for the third time that an increased amount of extra-axial cerebrospinal fluid (CSF) is associated with the diagnosis of autism spectrum disorder in young children. The ability to identify ASD children early could improve both treatment and quality of life. The study was published in the journal The Lancet Psychiatry.

Newswise: New Biomarker Panel Could Accelerate Autism Diagnoses
31-Aug-2018 4:30 PM EDT
New Biomarker Panel Could Accelerate Autism Diagnoses
UC Davis MIND Institute

Investigators at the UC Davis MIND Institute and NeuroPointDX, a division of Stemina Biomarker Discovery, have identified a group of blood metabolites that could help detect some children with autism spectrum disorder (ASD). Part of the Children’s Autism Metabolome Project (CAMP), the largest metabolomic ASD study ever attempted, these findings are a key step toward developing an ASD biomarker test. The research was published September 6 in the journal Biological Psychiatry.

Newswise: New Model Could Illuminate Autism Subtype
Released: 28-Jun-2018 2:05 PM EDT
New Model Could Illuminate Autism Subtype
UC Davis MIND Institute

Can a new mouse model provide essential insights into one type of autism spectrum disorder? UC Davis researchers hope their work yields new therapies for children.

Newswise: Immune System and Gastrointestinal Deregulation Linked with Autism
Released: 17-Apr-2018 3:05 PM EDT
Immune System and Gastrointestinal Deregulation Linked with Autism
UC Davis MIND Institute

Researchers at the UC Davis MIND Institute have found that children with autism spectrum disorder (ASD) have reduced immune system regulation, as well as shifts in their gut microbiota. The immune deregulation appears to facilitate increased inflammation and may be linked to the gastrointestinal issues so often experienced by children with ASD. The research was published in the journal Brain, Behavior, and Immunity.

Newswise: Amygdala Neurons Increase as Children Become Adults – Except in Autism
Released: 20-Mar-2018 12:00 PM EDT
Amygdala Neurons Increase as Children Become Adults – Except in Autism
UC Davis MIND Institute

In a striking new finding, researchers at the UC Davis MIND Institute found that typically-developing children gain more neurons in a region of the brain that governs social and emotional behavior, the amygdala, as they become adults. This phenomenon does not happen in people with autism spectrum disorder (ASD). Instead, children with ASD have too many neurons early on and then appear to lose those neurons as they become adults. The findings were published today in the journal Proceedings of the National Academy of Sciences (PNAS).

Newswise: Folic Acid May Mitigate Autism Risk From Pesticides
6-Sep-2017 3:05 PM EDT
Folic Acid May Mitigate Autism Risk From Pesticides
UC Davis MIND Institute

Researchers at UC Davis and other institutions have shown that mothers who take recommended amounts of folic acid around conception might reduce their children’s pesticide-related autism risk.

Newswise: UC Davis MIND Institute wins coveted ACE grant
Released: 7-Sep-2017 11:05 AM EDT
UC Davis MIND Institute wins coveted ACE grant
UC Davis MIND Institute

The UC Davis MND Institute has been awarded a 5-year, $12 million Autism Centers of Excellence (ACE) grant, one of five in the nation, to create a “Center for the Development of Phenotype-based Treatments of Autism Spectrum Disorder.”

Newswise:Video Embedded cerebrospinal-fluid-shows-promise-as-autism-biomarker
VIDEO
3-Mar-2017 4:00 PM EST
Cerebrospinal Fluid Shows Promise as Autism Biomarker
UC Davis MIND Institute

Researchers from the UC Davis MIND Institute, University of North Carolina (UNC) and other institutions have found that altered distribution of cerebrospinal fluid (CSF) in high-risk infants can predict whether they will develop autism spectrum disorder (ASD). The study appears today in the journal Biological Psychiatry.

Newswise: Placenta Provides Time Capsule for Autism Studies
Released: 17-Feb-2017 3:05 PM EST
Placenta Provides Time Capsule for Autism Studies
UC Davis MIND Institute

In two recent studies, researchers at UC Davis have shown that placental tissue can provide critical information about the epigenetic landscape that influences fetal development.

Newswise: Gram-Negative Bacteria May Influence Alzheimer’s Disease Pathology
Released: 29-Nov-2016 7:05 PM EST
Gram-Negative Bacteria May Influence Alzheimer’s Disease Pathology
UC Davis MIND Institute

For the first time, researchers have found higher levels of Gram-negative bacteria antigens in brain samples from late-onset Alzheimer’s disease patients. Compared to controls, patients with Alzheimer's had much higher levels of lipopolysaccharide (LPS) and E coli K99 pili protein. In addition, The UC Davis team also found LPS molecules congregated with amyloid plaques, which have been linked to Alzheimer’s pathology and progression. The research was published today in the print edition of the journal Neurology.

Newswise: Cognitive function tests reliable for people with intellectual disabilities, UC Davis research shows
Released: 6-Sep-2016 7:05 PM EDT
Cognitive function tests reliable for people with intellectual disabilities, UC Davis research shows
UC Davis MIND Institute

Researchers at the UC Davis MIND Institute have found that a battery of tests appears to have strong potential for measuring cognitive changes over time for people with intellectual disabilities. The work could open new doors to research into whether drugs and specialized educational programs or treatments can improve function in people with Down syndrome, fragile X syndrome and other causes of intellectual disabilities.

Newswise:Video Embedded sertraline-brand-named-zoloft-improves-functioning-in-young-children-with-fragile-x
VIDEO
Released: 26-Aug-2016 2:05 PM EDT
Sertraline, Brand Named Zoloft, Improves Functioning in Young Children with Fragile X
UC Davis MIND Institute

Treatment with sertraline may provide nominal but important improvements in cognition and social participation in very young children with fragile X syndrome, the most common genetic cause of intellectual disability and the leading single-gene cause of autism, a study by researchers with the UC Davis MIND Institute has found.

Newswise:Video Embedded digital-neurotherapeutic-in-development-at-the-uc-davis-mind-institute
VIDEO
Released: 22-Jun-2016 2:05 PM EDT
“Digital Neurotherapeutic” in Development at the UC Davis MIND Institute
UC Davis MIND Institute

A UC Davis researcher has created a video game for children who experience cognitive impairments from genetic disorders with the hope that that it will improve their ability to mentally process information about space and time.

Newswise: Distance Language Intervention Helps Adolescents with Disabilities Communicate
Released: 27-Apr-2016 6:05 PM EDT
Distance Language Intervention Helps Adolescents with Disabilities Communicate
UC Davis MIND Institute

To address the deficit of interventions for older children and adolescents with fragile X, MIND Institute researcher Andrea McDuffie and colleagues created an intervention that uses a shared storytelling paradigm and real-time parent coaching, all provided in the home through telecommunications. The small but important study found that the intervention improved adolescent boys’ abilities to produce longer sentences, use more diverse vocabulary and concentrate for longer time periods during conversational interactions.

Newswise: Autism Awareness Month Experts Available for Interviews
Released: 14-Apr-2016 2:05 PM EDT
Autism Awareness Month Experts Available for Interviews
UC Davis MIND Institute

Two autism experts from the UC Davis MIND Institute are available for interviews during Autism Awareness Month


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