Latest News from: University of California, Los Angeles (UCLA), Health Sciences

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Newswise: UCLA-Easton Center names new director to lead Alzheimer’s research
Released: 22-Sep-2020 2:45 PM EDT
UCLA-Easton Center names new director to lead Alzheimer’s research
University of California, Los Angeles (UCLA), Health Sciences

Dr. Keith Vossel, who is known for his discovery that many Alzheimer’s patients experience nighttime seizures that disrupt their sleep, is the new director of the Mary S. Easton Center for Alzheimer’s Disease Research at UCLA.

Newswise: Scientists awarded $52M NIH grant to study schizophrenia cause and effect
Released: 15-Sep-2020 5:25 PM EDT
Scientists awarded $52M NIH grant to study schizophrenia cause and effect
University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers and their colleagues from two other institutions have been awarded a $52 million grant from the National Institutes of Health to lead an international study to better understand the cause and effect of schizophrenia in high-risk youth.

Released: 14-Sep-2020 11:40 AM EDT
UCLA joins nationwide clinical trial to study course of COVID-19 in people with cancer
University of California, Los Angeles (UCLA), Health Sciences

To help better understand the impact and outcomes of COVID-19 in people undergoing cancer treatment, UCLA are participating in a NCI study with cancer centers across the country.

Newswise: UCLA study shows how interferon-gamma guides response to cancer immunotherapy
3-Sep-2020 3:05 PM EDT
UCLA study shows how interferon-gamma guides response to cancer immunotherapy
University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers shed light on how interferon-gamma (IFN-y) guides the treatment response in people with advanced melanoma who are treated with one of the leading immunotherapies — immune checkpoint blockade.

8-Sep-2020 5:25 PM EDT
COVID-19 may have been in L.A. as early as last December, UCLA-led study suggests
University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers and colleagues who analyzed electronic health records found that there was a significant increase in patients with coughs and acute respiratory failure at UCLA Health hospitals and clinics beginning in late December 2019, suggesting that COVID-19 may have been circulating in the area months before the first definitive cases in the U.S. were identified. This sudden spike in patients with these symptoms, which continued through February 2020, represents an unexpected 50% increase in such cases when compared with the same time period in each of the previous five years.

Newswise: People with Anorexia Nervosa and Body Dysmorphic Disorder Show Similarities and Differences in Brain Function
Released: 8-Sep-2020 2:50 PM EDT
People with Anorexia Nervosa and Body Dysmorphic Disorder Show Similarities and Differences in Brain Function
University of California, Los Angeles (UCLA), Health Sciences

A new UCLA study shows partially overlapping patterns of brain function in people with anorexia nervosa and those with body dysmorphic disorder, a related psychiatric condition characterized by misperception that particular physical characteristics are defective.

Newswise: UCLA Cannabis Research Initiative launches COVID-19 survey
Released: 3-Sep-2020 7:05 PM EDT
UCLA Cannabis Research Initiative launches COVID-19 survey
University of California, Los Angeles (UCLA), Health Sciences

To better understand the effect of the COVID-19 pandemic on cannabis and CBD use, the UCLA Cannabis Research Initiative has launched the Cannabis, CBD and COVID Survey.

Newswise: Older adults with existing depression show resilience during the pandemic
Released: 18-Aug-2020 6:05 PM EDT
Older adults with existing depression show resilience during the pandemic
University of California, Los Angeles (UCLA), Health Sciences

Study finds that older adults with depression are showing resilience during the COVID-19 pandemic.

Released: 12-Aug-2020 12:10 PM EDT
Grant boosts psychosocial care resources during COVID-19 pandemic
University of California, Los Angeles (UCLA), Health Sciences

The Simms/Mann-UCLA Center for Integrative Oncology has received a $50,000 grant from Los Angeles-based PHASE ONE Foundation to support psychosocial care for people with cancer, their families and frontline healthcare workers during the COVID-19 pandemic.

Newswise: Test accurately IDs people whose gonorrhea can be cured with simple oral antibiotic
4-Aug-2020 7:10 PM EDT
Test accurately IDs people whose gonorrhea can be cured with simple oral antibiotic
University of California, Los Angeles (UCLA), Health Sciences

A test designed by UCLA researchers can pinpoint which people with gonorrhea will respond successfully to the inexpensive oral antibiotic ciprofloxacin, which had previously been sidelined over concerns the bacterium that causes the infection was becoming resistant to it.

Newswise: Chemotherapy is used to treat less than 25% of people with localized sarcoma
Released: 6-Aug-2020 12:45 PM EDT
Chemotherapy is used to treat less than 25% of people with localized sarcoma
University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers have found that chemotherapy is not commonly used when treating adults with localized sarcoma, a rare type of cancer of the soft tissues or bone. In a nationwide analysis of nearly 20,000 patients whose cancer had not yet spread to other organs, the scientists learned that only 22% were treated with some form of chemotherapy.

Newswise: UCLA launches major mental health study to discover insights about depression
Released: 4-Aug-2020 4:35 PM EDT
UCLA launches major mental health study to discover insights about depression
University of California, Los Angeles (UCLA), Health Sciences

UCLA has launched a major new study, sponsored by and in collaboration with Apple, designed to help revolutionize detection and treatment of depression.

Released: 4-Aug-2020 11:55 AM EDT
ACTG Announces Launch of Novel Clinical Trial Testing Multiple Therapeutics to Treat COVID-19
University of California, Los Angeles (UCLA), Health Sciences

The AIDS Clinical Trials Group (ACTG) has initiated the ACTIV-2 Outpatient Monoclonal Antibodies and Other Therapies Trial. ACTIV-2 includes both phase 2 and phase 3 evaluations of multiple promising investigational agents for treating early COVID-19 in a single trial.

Newswise:  UCLA researchers receive $2.97 million grant to develop test for early detection of liver cancer
Released: 4-Aug-2020 11:40 AM EDT
UCLA researchers receive $2.97 million grant to develop test for early detection of liver cancer
University of California, Los Angeles (UCLA), Health Sciences

UCAL researchers are developing a nanotechnology-enabled cancer diagnostic solution that will help detect early stage liver cancer for people who are at risk of developing the disease.

Newswise: Psychology of Masking: Why Some People Don’t Cover Up
Released: 28-Jul-2020 3:50 PM EDT
Psychology of Masking: Why Some People Don’t Cover Up
University of California, Los Angeles (UCLA), Health Sciences

Although discomfort, confusion and even political affiliation are often cited as reasons that make people less likely to wear a mask in public, the psychological traits that shape a person’s behavioral choices may also factor into the decision.

Released: 27-Jul-2020 5:05 PM EDT
Brain changes in Alzheimer’s disease may lead to new drug targets
University of California, Los Angeles (UCLA), Health Sciences

A team of UCLA neurologists have uncovered new potential drug targets in the brains of patients with Alzheimer’s disease, after testing more than a thousand patient samples

Newswise: How airway cells work together in regeneration and aging
Released: 27-Jul-2020 3:55 PM EDT
How airway cells work together in regeneration and aging
University of California, Los Angeles (UCLA), Health Sciences

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified the process by which stem cells in the airways of the lungs switch between two distinct phases — creating more of themselves and producing mature airway cells — to regenerate lung tissue after an injury.

Newswise: Fine-tuning adoptive cell therapy for advanced cancers
Released: 22-Jul-2020 12:10 PM EDT
Fine-tuning adoptive cell therapy for advanced cancers
University of California, Los Angeles (UCLA), Health Sciences

In a new study looking at adoptive cell transfer products bearing a transgenic T-cell receptor (TCR), researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a discordant phenomenon in which a subset of patients displayed profoundly decreased expression of the transgenic TCR over time, despite the transgenic TCR being present at the DNA level.

Newswise: Coronavirus antibodies fall dramatically in first 3 months after mild cases of COVID-19
Released: 21-Jul-2020 4:50 PM EDT
Coronavirus antibodies fall dramatically in first 3 months after mild cases of COVID-19
University of California, Los Angeles (UCLA), Health Sciences

A study by UCLA researchers shows that in people with mild cases of COVID-19, antibodies against SARS-CoV-2 — the virus that causes the disease — drop sharply over the first three months after infection, decreasing by roughly half every 36 days on average. If sustained at that rate, the antibodies would disappear within about a year.

Newswise: Researchers ID new target in drive to improve immunotherapy for cancer
17-Jul-2020 6:10 PM EDT
Researchers ID new target in drive to improve immunotherapy for cancer
University of California, Los Angeles (UCLA), Health Sciences

Researchers at the UCLA Jonsson Comprehensive Cancer Center and UCLA School of Dentistry have identified a potential new combination therapy to treat advanced head and neck squamous cell carcinoma, the most common type of head and neck cancer.

Newswise: Doctors motivated by both health, malpractice concerns when ordering additional tests
Released: 17-Jul-2020 8:45 PM EDT
Doctors motivated by both health, malpractice concerns when ordering additional tests
University of California, Los Angeles (UCLA), Health Sciences

A UCLA-led study has found that dermatopathologists, who specialize in diagnosing skin diseases at the microscopic level, are motivated both by patient safety concerns and by malpractice fears — often simultaneously — when ordering multiple tests and obtaining second opinions, with a higher proportion of these doctors reporting patient safety as a concern. When ordering additional microscopic tests for patients, 90% of the dermatopathologists surveyed cited patient safety as a concern and 71% of them reported malpractice fears. Similarly, when obtaining second reviews from a consulting pathologist or recommending additional surgical sampling, 91% cited safety concerns and 78% malpractice concerns.

Newswise: Team Sports Risks Go Well Beyond Injury During the Pandemic
Released: 9-Jul-2020 6:25 PM EDT
Team Sports Risks Go Well Beyond Injury During the Pandemic
University of California, Los Angeles (UCLA), Health Sciences

Annabelle de St. Maurice, MD, MPH, co-chief infection prevention officer for UCLA Health, speaks on The Centers for Disease Control and Prevention's guide for youth sports to resume.

Newswise: Welcome, Robin the AI robot
Released: 7-Jul-2020 2:05 PM EDT
Welcome, Robin the AI robot
University of California, Los Angeles (UCLA), Health Sciences

In response to the COVID-19 pandemic, UCLA Mattel Children’s Hospital launched an innovative project to support the emotional needs of children through a new AI powered robot. Robin’s technology enables the robot to build what is called associative memory — it recognizes a child’s emotions by interpreting his or her facial expressions and builds responsive dialogue by replicating patterns formed from previous experiences.

Newswise: How the body regulates scar tissue growth after heart attacks
Released: 3-Jul-2020 11:35 AM EDT
How the body regulates scar tissue growth after heart attacks
University of California, Los Angeles (UCLA), Health Sciences

New UCLA research conducted in mice could explain why some people suffer more extensive scarring than others after a heart attack. The study, published in the journal Cell, reveals that a protein known as type 5 collagen plays a critical role in regulating the size of scar tissue in the heart.

Newswise: Study pinpoints new function for histones
Released: 2-Jul-2020 4:05 PM EDT
Study pinpoints new function for histones
University of California, Los Angeles (UCLA), Health Sciences

Scientists discovered that histones act as an enzyme that converts copper into a form that can be used by the cells. The finding refutes earlier theories that copper spontaneously converts in the body into a usable state.

Newswise: School HPV vaccine policies could result in higher vaccination rates, reduction in cancers
Released: 29-Jun-2020 7:35 PM EDT
School HPV vaccine policies could result in higher vaccination rates, reduction in cancers
University of California, Los Angeles (UCLA), Health Sciences

A UCLA-led study has found that in 2 of 3 states and jurisdictions with policies that require students entering school to receive the human papillomavirus vaccine, vaccination rates among 13-to-17-year-olds were significantly higher than in surrounding states without such policies.

Newswise: UCLA survey seeks public opinion on allocating resources during COVID-19
Released: 29-Jun-2020 11:05 AM EDT
UCLA survey seeks public opinion on allocating resources during COVID-19
University of California, Los Angeles (UCLA), Health Sciences

As California prepares for a potential surge of COVID-19, there is a pressing need to determine how critical care resources should be allocated, especially if there is an extreme shortage of those resources.

Released: 29-Jun-2020 9:00 AM EDT
Supporting LGBTQ+ youth who are Black, Indigenous and people of color
University of California, Los Angeles (UCLA), Health Sciences

Youth who are Black, Indigenous and people of color (BIPOC) that also identify as LGBTQ+ representation of sexual orientations and gender identities experience higher rates of social discrimination and isolation, including bullying, family rejection and a lack of social support. Here are ways that family and friends can support them.

Released: 25-Jun-2020 7:05 PM EDT
States with the highest income inequality also experienced a larger number of COVID-19 deaths
University of California, Los Angeles (UCLA), Health Sciences

States with the highest level of income inequality had a larger number of COVID-19-related deaths compared with states with lower income inequality. New York state, with the highest income inequality, had a mortality rate of 51.7 deaths per 100,000 vs. Utah, the state with the lowest income inequality and which had a mortality of 0.41 per 100,000.

Newswise: New technique allows scientists to measure mitochondrial respiration in frozen tissue
Released: 22-Jun-2020 6:50 PM EDT
New technique allows scientists to measure mitochondrial respiration in frozen tissue
University of California, Los Angeles (UCLA), Health Sciences

UCLA scientists have developed a method for restoring oxygen-consumption activity to previously frozen mitochondria samples. By speeding up research, investigators hope to accelerate the diagnosis of people living with mitochondrial diseases and secondary disorders in which mitochondria play a key role, including diseases related to aging, metabolism and the heart.

Released: 22-Jun-2020 5:50 PM EDT
ACTG Studies at AIDS 2020: Virtual
University of California, Los Angeles (UCLA), Health Sciences

Topics include the efficacy and safety of third-line treatment regimens in resource-limited settings, viral rebound rates after treatment interruption of modern ART, and whether a standardized frailty score can improve clinicians’ ability to estimate cardiovascular risk among older people with HIV.

Newswise: Homeless people are more likely to be put on ventilators for respiratory infections than non-homeless
Released: 17-Jun-2020 5:40 PM EDT
Homeless people are more likely to be put on ventilators for respiratory infections than non-homeless
University of California, Los Angeles (UCLA), Health Sciences

Researchers from UCLA, Harvard Medical School and the University of Tokyo found that during a recent six-year period, homeless people in New York state were more likely to hospitalized and treated with mechanical ventilators for respiratory infections than people who are not homeless. These findings have implications for the COVID-19 pandemic.

Newswise: UCLA receives nearly $14 million from NIH to investigate gene therapy to combat HIV
Released: 15-Jun-2020 5:10 PM EDT
UCLA receives nearly $14 million from NIH to investigate gene therapy to combat HIV
University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers and colleagues have received a $13.65 million grant from the National Institutes of Health to investigate and further develop an immunotherapy known as CAR T, which uses genetically modified stem cells to target and destroy HIV.

Newswise: UCLA Health’s Dr. Clara Lajonchere elected Chair of the California Precision Medicine Advisory Council
Released: 11-Jun-2020 7:05 PM EDT
UCLA Health’s Dr. Clara Lajonchere elected Chair of the California Precision Medicine Advisory Council
University of California, Los Angeles (UCLA), Health Sciences

Dr. Clara Lajonchere, deputy director of the Institute for Precision Health at UCLA Health, has been elected chair of the new California Precision Medicine Advisory Council.

Newswise: Reprogramming of Immune System Cures Child with Often-Fatal Fungal Infection
10-Jun-2020 1:00 PM EDT
Reprogramming of Immune System Cures Child with Often-Fatal Fungal Infection
University of California, Los Angeles (UCLA), Health Sciences

In the June 11 issue of the New England Journal of Medicine, a team of UCLA physicians and scientists describes the first case of immune modulation being used to cure a severe and often fatal fungal infection. The team “retuned” a 4-year-old’s immune system so that it could fight off disseminated coccidioidomycosis.

Released: 8-Jun-2020 3:05 PM EDT
Innovative Project Solves UCLA Health’s COVID-19 Testing Swab Shortage With 3D-Printed Swabs
University of California, Los Angeles (UCLA), Health Sciences

UCLA Health has been granted permission from the Food and Drug Administration to use a 3D printed design for COVID-19 testing swabs. The effort was led by a fellow from the UCLA Biodesign program.

Newswise: Some types of prostate cancer may not be as aggressive as originally thought
Released: 4-Jun-2020 11:25 AM EDT
Some types of prostate cancer may not be as aggressive as originally thought
University of California, Los Angeles (UCLA), Health Sciences

Researchers at the UCLA Jonsson Comprehensive Cancer Center analyzed gene-expression patterns in the most aggressive prostate cancer grade group — known as Gleason grade group 5 — and found that this grade of cancer can actually be subdivided into four subtypes with distinct differences. The findings may affect how people are treated for the disease.

Newswise: Cognitive behavior therapy tops other psychotherapies in reducing inflammation
3-Jun-2020 9:00 AM EDT
Cognitive behavior therapy tops other psychotherapies in reducing inflammation
University of California, Los Angeles (UCLA), Health Sciences

A review of 56 randomized clinical trials finds that psychological and behavioral therapies may be effective non-drug treatments for reducing disease-causing inflammation in the body.

Newswise: Swelling of Tissues Drives Immune System Activity, UCLA Researchers Find
Released: 2-Jun-2020 1:30 PM EDT
Swelling of Tissues Drives Immune System Activity, UCLA Researchers Find
University of California, Los Angeles (UCLA), Health Sciences

A UCLA research team has identified a new paradigm for understanding the regulation of the immune system, potentially paving the way for new approaches to treating infections and immune-related diseases such as type 1 diabetes and certain cancers.

Newswise: New drug combinations help overcome resistance to immunotherapy
Released: 28-May-2020 11:55 AM EDT
New drug combinations help overcome resistance to immunotherapy
University of California, Los Angeles (UCLA), Health Sciences

A new study from researchers at the UCLA Jonsson Comprehensive Cancer Center helps explain how disruptions in genes can lead to the resistance to one of the leading immunotherapies, PD-1 blockade, and how new drug combinations could help overcome resistance to the anti-PD-1 therapy in a mechanistically-based way.

Released: 20-May-2020 6:05 PM EDT
$5.75M grant to help researchers study role of obesity in development of pancreatic cancer
University of California, Los Angeles (UCLA), Health Sciences

A team of researchers from the UCLA Jonsson Comprehensive Cancer Center and peer institutions has been awarded a $5.75 million grant from the National Cancer Institute to study the correlation between obesity, inflammation and pancreatic cancer. The scientists hope their findings may help people avoid getting this cancer.

Newswise: Scientists find evidence of link between diesel exhaust, risk of Parkinson’s
Released: 19-May-2020 8:05 PM EDT
Scientists find evidence of link between diesel exhaust, risk of Parkinson’s
University of California, Los Angeles (UCLA), Health Sciences

A new UCLA study in zebrafish has identified the process by which air pollution can damage brain cells, potentially contributing to Parkinson’s disease.


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