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When researchers from UCLA and the Laureate Institute for Brain Research in Tulsa, Oklahoma, wanted to test an app they created to measure body image perception, they went to the body image experts — fashion models.

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Nearly 98% percent of people prescribed direct-acting oral anticoagulants such as apixaban used over-the-counter products. Of those, 33% took at least one such product that, in combination with the anticoagulants, could cause dangerous internal bleeding.

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Thiazide diuretics demonstrate better effectiveness and cause fewer side effects than ACE inhibitors as first-line antihypertensive drugs, according to a report published Oct. 24 in The Lancet. Marc A. Suchard, MD, PhD, professor of biostatistics at the UCLA Fielding School of Public Health served as lead author.of the study.

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A UCLA-led study finds that, with the use of MRI scans, it is possible to distinguish between memory loss caused by Alzheimer’s disease and traumatic brain injury.

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The study, conducted in mice, is the first to show that creatine uptake is critical to the anti-tumor activities of killer T cells, the foot soldiers of the immune system.

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A new study examining the role that star-shaped brain cells called astrocytes play in Huntington’s disease has identified a potential strategy that may halt the disease and repair some of the damage it causes.

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This month, the UCLA Jonsson Cancer Center has launched a pioneering chimeric antigen receptor (CAR) T cell immunotherapy trial that will attack cancer cells by simultaneously recognizing two targets – CD19 and CD20 – that are expressed on B-cell lymphoma and leukemia.

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Now, in experiments in mice as well as isolated human cancer cells, UCLA researchers have discovered a way to eliminate the CML stem cells. Their approach uses an antibody to block a protein that the stem cells rely on to grow. The advance, described in a study published in the Journal of Clinical Investigation, might eventually help treat not only chronic myelogenous leukemia but other cancers as well.

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A new study led by UCLA researchers, have found that obtaining a second opinion from pathologists who are board certified or have fellowship training in dermatopathology can help improve the accuracy and reliability of diagnosing melanoma, one of the deadliest and most aggressive forms of skin cancer.

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Researchers from the UCLA Jonsson Comprehensive Cancer Center and other institutions in the U.S., Canada, the United Kingdom and Singapore, have identified 1,178 biomarkers in men’s genomes — the complete set of genetic material inherited from one’s parents — that predict how an individual person’s prostate cancer will grow. The finding suggests that predicting how a person’s cancer will evolve may lie in their inherited DNA.

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Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered a molecular process that controls the rate at which nerves grow both during embryonic development and recovery from injury throughout life.

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A study led by UCLA researchers found that adding ribociclib, a targeted therapy drug, to standard hormone therapy has been shown to significantly improve overall survival in postmenopausal women with advanced hormone-receptor positive/HER2- breast cancer, one of the most common forms of the disease.

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Scientists from the UCLA Integrated Substance Abuse Programs will lead a $25 million National Institutes of Health study testing treatments, including the use of telemedicine, to help fight the opioid epidemic in rural America.

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UCLA researchers have identified a new drug delivery pathway that may help stop tumor growth and keep cancer from coming back in mice.

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In experiments with mice, UCLA researchers have shown they can harness the power of iNKT cells to attack tumor cells and treat cancer. The new method, described in the journal Cell Stem Cell, suppressed the growth of multiple types of human tumors that had been transplanted into the animals.

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Seven years ago, Jason Esterhuizen was in a horrific car crash that destroyed his eyes, plunging him into total darkness. Today, he’s regained visual perception and more independence, thanks to an experimental device implanted in his brain by researchers at UCLA Health.

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A UCLA-led study has found that using three-dimensional virtual reality models to prepare for kidney tumor surgeries resulted in substantial improvements, including shorter operating times, less blood loss during surgery and a shorter stay in the hospital afterward.

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Physician-scientist Dr. Dennis Slamon, has been awarded the 2019 Lasker-DeBakey Clinical Medical Research Award for the groundbreaking development of breast cancer drug Herceptin (trastuzumab), a life-saving therapy for women with HER2-positive breast cancer.

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UCLA has been awarded a grant from the U.S. Department of Commerce’s Economic Development Administration to create a regional hub for the development of medical technology and digital health tools.

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Dozens of countries lack important legal protections against children doing work that could be harmful or interfere with their education, according to a study by the WORLD Policy Analysis Center at UCLA.

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In a new book edited by a professor from the UCLA Fielding School of Public Health, academicians and community organizers explain how public health practitioners can identify and address racism.

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A drug developed by UCLA physician-scientists and chemists speeds up the regeneration of mouse and human blood stem cells after exposure to radiation. If the results can be replicated in humans, the compound could help people recover quicker from chemotherapy, radiation and bone marrow transplants.

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Researchers developed a drug delivery system that can break through the blood-brain barrier in mice.

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A comprehensive dementia care program staffed by nurse practitioners working within a health system improves the mental and emotional health of patients and their caregivers.

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A Veterans Health Administration program that added mental health specialists, care managers or both in primary care clinics significantly improved access to mental health and primary care services to veterans with behavioral health needs. The practice also resulted in 9% higher average annual costs for each patient.

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UCLA researchers have developed an artificial intelligence system that could help pathologists read biopsies more accurately and to better detect and diagnose breast cancer.

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A research team has identified dozens of genes, including 16 new genes that increase the risk of autism spectrum disorder.

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The prostates of older mice contain more luminal progenitor cells — cells capable of generating new prostate tissue — than the prostates of younger mice, UCLA researchers have discovered.

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Researchers from the UCLA Jonsson Comprehensive Cancer Center undertook a head-to-head comparison of two imaging techniques and have concluded that prostate-specific membrane antigen imaging is more effective in detecting the location of the prostate cancer recurrence.

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UCLA hospitals rank #1 in L.A. and California, #6 in nation. For 30th consecutive year, U.S. News & World Report places UCLA on national honor roll reserved for top medical centers.

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A UCLA-led research team has found that giving mice antibiotics for 10 days prior to a liver transplant leads to better liver function after the surgery -- then they came across data that it also works in humans. It's all linked to the antibiotics' effect on the microbiome.

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Using an ultra-sensitive and high-throughput isolation technology, UCLA researchers were able to characterize and identify the neoantigens driving the antitumor responses in a patient treated with anti-PD-1 blockade and isolate the T cell receptors responsible for such effect.

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New research suggests that 32% of children up to the age of 3 years who were exposed to the Zika virus during the mother’s pregnancy had below-average neurological development. Also, fewer than 4% of 216 children evaluated had microcephaly —a smaller-than-normal head that is one of the hallmarks of the mosquito-borne disease. The heads of two of those children grew to normal size over time, the researchers reported.

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An interdisciplinary team of UCLA scientists has found that small cell neuroendocrine cancers from a range of tissues have a common molecular signature and share drug sensitivities with blood cancers.

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A team of researchers from UCLA and the University of Toronto have identified a new biomarker found in urine that can help detect aggressive prostate cancer, potentially saving hundreds of thousands of men each year from undergoing unnecessary surgeries and radiotherapy treatments.

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Dr. Beth Karlan, the newly appointed director of cancer population genetics at UCLA’s Jonsson Comprehensive Cancer Center, is hopeful that her research will not only help women get diagnosed with ovarian cancer at an earlier stage, but also identify the women who are most at-risk so they can intervene before the cancer even develops.

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Air quality samples collected near the Aliso Canyon natural gas storage facility during the 2015 blowout that led to the largest-known human-caused release of methane in U.S. history showed elevated levels of pollutants known or suspected to be associated with serious health problems

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UCLA researchers have published a Cell study showing that the brains of pairs of animals synchronize during social situations. The level of synchronization actually predicted how much the animals would interact.

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Each year, 1M men in the U.S. undergo biopsies for prostate cancer. UCLA physicians have found that a new biopsy method, which includes biopsy guided by magnetic resonance imaging (MRI), can be used together with the traditional method to increase the rate of prostate cancer detection.

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Twelve years after the landmark Convention on the Rights of Persons with Disabilities, UCLA WORLD Policy Analysis Center finds evidence of marked progress -- but gaps remain leaving more than 160 million people behind

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A UCLA-led research team has pinpointed a three-drug combination that could prove to be an effective new therapy for people with a specific type of advanced melanoma.

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Results of a phase 3 clinical trial by researchers at UCLA’s Jonsson Comprehensive Cancer Center found that women with HER2-positive breast cancer had significantly better response rates, but more severe side effects, when they were treated with traditional neoadjuvant chemotherapy along with dual HER2-targeted blockade, compared to a more novel approach using HER2-targeted chemotherapy plus HER2-targeted blockade.

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In a study led by UCLA investigators, treatment with the immunotherapy drug pembrolizumab helped more than 15% of people with advanced non-small cell lung cancer live for at least five years — and 25% of patients whose tumor cells had a specific protein lived at least that long.

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A UCLA-led study has found that using a drug called ribociclib in combination with a common hormone therapy may help premenopausal women with the most common type of breast cancer live longer than if they only receive the hormone therapy.

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Waze, the crowdsourced traffic application, could potentially help first responders reach a car crash in half the time it currently takes compared with reports received by the California Highway Patrol emergency personnel.

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In a new study published by European Urology, UCLA researchers and colleagues from ten other institutions examined the protocol for treating aggressive prostate cancer. With aggressive forms of this disease, it is often unclear if radiation therapy should be applied to the prostate alone or to the whole pelvis. The reason a low-dose of radiation may be applied to the whole pelvis is that pelvic lymph nodes may have microscopic cancer cells within them.

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Private insurers covering people receiving treatment for dialysis paid four times more than government insurance programs such as Medicare paid for the same service. Government programs paid, on average, $248 per dialysis session, compared with $1,041 per session for people with private insurance.