High response rates for patients with stage 4 lung cancer after anti-inflammatory drug added temporarily to immune checkpoint inhibitor therapy
As a new space race revs up, propelling humans back to the Moon and toward a Mars landing for the first time, mysteries remain about the unique pressures of spaceflight on humans – especially for those blasting off through new commercial space travel operations. For the first time, researchers have data on the physical and psychological impact of spaceflight on an all-civilian crew.
Almost a century ago, the discovery of antibiotics like penicillin revolutionized medicine by harnessing the natural bacteria-killing abilities of microbes. Today, a new study co-led by researchers at the Perelman School of Medicine at the University of Pennsylvania suggests that natural-product antibiotic discovery is about to accelerate into a new era, powered by artificial intelligence (AI).
In their pursuit to discover the mechanism behind how RVCL does its damage, researchers found some clues to the DNA damage theory of aging
Physical and sexual abuse, having parents who misuse substances, and witnessing violent crime are tragic events that don’t remain locked in a single point in time. Rather, they are termed adverse childhood experiences (ACEs) and 64 percent of American adults who participated in a recent survey reported experiencing at least one ACE prior to turning 18 years old.
Penn Medicine helps bridge medical science with the arts in the world’s first project to image double basses.
A new “armored” form of CAR T cell therapy may be able to help patients with non-Hodgkin lymphoma whose cancers do not respond to currently available CAR T cell therapies. The Phase I clinical trial was presented at the 2024 ASCO Annual Meeting.
Leading experts in transplant from Penn Medicine will converge in the Pennsylvania Convention Center in Philadelphia from June 1-5 for the American Transplant Congress. The event is the Joint Annual meeting of the American Society of Transplant Surgeons and the American Society of Transplantation.
Penn Medicine will once again join with community partners and Siemens Healthineers to host a free mammogram clinic and community health fair in June, giving the West Philadelphia and Upper Darby communities convenient access to health screenings right in their neighborhoods.
Six hospitals in the University of Pennsylvania Health System (UPHS) earned perfect scores as part of Penn Medicine once again being named a 2024 LGBTQ+ Healthcare Equality Leader by the Human Rights Campaign (HRC) Foundation.
Researchers from Penn Medicine’s Abramson Cancer Center (ACC) and the Perelman School of Medicine at the University of Pennsylvania will present data on the latest advances in cancer research at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, happening May 31—June 4, 2024 in Chicago and online.
An experimental mRNA vaccine against avian influenza virus H5N1 is highly effective in preventing severe illness and death in preclinical models. The vaccine could potentially help manage the outbreak of the H5N1 virus currently circulating in birds and cattle in the United States, and prevent human infections with the virus.
In a trial analyzing how messages were framed in an underserved population, offering colorectal cancer screening options resulted in the highest screening rate
Researchers from the Gene Therapy Program (GTP) at the Perelman School of Medicine at the University of Pennsylvania will present ten research abstracts, two invited talks, and a workshop presentation highlighting their translational science and discovery research on gene therapy, gene editing, and adeno-associated virus (AAV) vector technology at the American Society of Cell and Gene Therapy (ASGCT) 27th Annual Meeting on May 7 - 11, 2024 in Baltimore, Maryland.
Mitchell Schnall, MD, PhD, has been appointed to a newly created role as Senior Vice President for Data and Technology Solutions for the University of Pennsylvania Health System (UPHS), following two terms as Chair of Radiology in Penn’s Perelman School of Medicine. In his new role, he will lead teams and projects that will pave a path for Penn Medicine to lead the health care industry into a new, technology- and data-driven era.
When one study says a treatment works, but another says it doesn’t (or worse), how are clinicians supposed to determine what they should do? A Penn Medicine team recently received funding from PCORI to build a guide system for these situations
In a public commitment to become the most environmentally friendly health care organization in the nation and lead the industry to reduce its outsized impact on climate change, Penn Medicine has signed the ambitious Health Sector Climate Pledge, promising to significantly cut and, eventually, eliminate its carbon emissions by 2042.
Liver inflammation, a common side-effect of cancers elsewhere in the body, has long been associated with worse cancer outcomes and more recently associated with poor response to immunotherapy. Now, a team led by researchers from the Abramson Cancer Center and Perelman School of Medicine at the University of Pennsylvania has found a big reason why.
Mitchell A. Lazar, M.D., Ph.D., the Rhoda and Willard Ware Professor in Diabetes and Metabolic Disease, and Director of the Institute for Diabetes, Obesity, and Metabolism in the Perelman School of Medicine at the University of Pennsylvania, is the 2025 recipient of the George M. Kober Medal from the Association of American Physicians (AAP). Lazar will receive the honor in Chicago at the AAP’s annual meeting which takes place April 25-27, 2025.
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