Articles on personal care product chemicals; PBPK modeling; 2D vs 3D for drug-induced liver injury; zebrafish and drug discovery; glutathione restoration and acetaminophen; high-throughput screening for thyroid hormone T4; and genetically engineered food crops featured in new Toxicological Sciences.
The Toxicological Sciences 20th anniversary celebration continues with articles on mitochondrial toxicity and organophosphorus compounds, in addition to featured papers on metabolic syndrome; paternal exposures and offspring’s mitochondria; data fusion and AOPs; DNA damage assay predictability; and imaging mammary epithelial organoids.
Despite a worldwide increase in individuals aged 60 or older, few issues in toxicological science associated with the aging process have been addressed, and the elderly remain a largely understudied, vulnerable population. SOT hosting meeting to discuss research and issues related to this topic.
With more than 6,500 individuals from around the world in attendance, the Society of Toxicology (SOT) 57th Annual Meeting and ToxExpo will feature leading experts from across the broad range of disciplines and specialties that inform and advance toxicology.
January 2018 issue of SOT journal honors the publication's 20-year history and features the newest, groundbreaking research in toxicology.
Through its awards, SOT honors more than two dozen groundbreaking scientists, emerging leaders, postdoctoral researchers, and graduate students who are advancing the science of toxicology. The SOT Awards also recognize the contributions of educators and science communicators as they work to encourage students to pursue STEM careers and improve public understanding of the connection between scientific research and public health.
The Society of Toxicology (SOT) has approved a new Issue Statement on the issues and complexities associated with understanding the health risk from low-level arsenic exposure.
The Society of Toxicology (SOT) has approved a new Issue Statement on food and feed safety related to genetically engineered (GE) crops (commonly referred to as GMOs). The Society's journal, Toxicological Sciences, also has published a new forum article that provides an in-depth review of 20+ years of GE research.
Editor's Highlights include papers on aryl hydrocarbon receptor activation and neutrophil function; transcriptomic analysis of TCE and PCE in the liver and kidney; functional genomics of TCE metabolites genotoxicity; and increased aflatoxin b1 damage in pregnant mice.
The October 2017 issue of Toxicological Sciences (Vol. 159, Issue 2) includes a wide range of articles on topics representing the latest in toxicological research and advances.
Scientific research and publishing over the past decade has experienced some substantial transformations—and not in a good way. With an increasing number of poor-quality scientific journals appearing in the marketplace, it is important to know how to recognize potential scams.
With increasing reports of and concerns about opioid abuse, there are actions toxicologists can take to help prevent and treat the problem.
A rise in caloric consumption combined with a decrease in physical activity has contributed to a boom of metabolic diseases, such as type 2 diabetes mellitus and cardiovascular diseases (e.g., heart failure and stroke).
The later-in-life effects of early life exposure to inorganic arsenic, reducing the toxicity of cancer treatments, advances in organs-on-a-chip and other alternative test methods, how to translate in vitro research to real-world understanding, controversies in pesticide toxicology, and the reproductive and developmental effects of botanical dietary supplements are just a few of the cutting-edge scientific topics being explored at the Society of Toxicology (SOT) 56th Annual Meeting and ToxExpo.
The 2017 SOT Awards recipients have studied the role of pesticide exposure on neurodegenerative diseases, connections between chemicals and the susceptibility to allergies and asthma, risk assessment, alternative test methods and strategies, and more, in their efforts to improve public, animal and environmental health.
Toxicologists who research health, exposure-related disease, and susceptibility are actually concurrently studying the consequences of epigenetic regulation, which is why an understanding of toxicoepigenetics is so important.
There generally are two approaches used to indirectly assess proarrhythmic risk, but some researchers believe that human induced pluripotent stem-cell derived (hiPSC)-cardiomyocytes offer an opportunity to change the paradigm.
SOT congrats Congress and President Obama for the passage and adoption of the Frank R. Lautenberg Chemical Safety for the 21st Century Act. The bill contains strong, objective, scientific underpinnings and will protect public health for years to come.
For the last several years, an SOT Task Force has been serving as a resource to members of Congress working on a bill for chemical safety reform. The compromise bill being voted on this week by the US Congress "will protect public health for years to come," says SOT leadership.
Alternative methods to animal testing, how epigenomic exposures impact health, safety of toxic metals in foods, effects of exposures to nanoparticles, generational effects of environmental exposures, and the toxicological effects of manmade and natural disasters are the topics of some of the more than 170 scientific sessions being conducted at the 55th Annual Meeting and ToxExpo of the Society of Toxicology (SOT), March 13–17, 2016, at the Ernest N. Morial Convention Center in New Orleans, Louisiana.
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