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University Hospitals in Cleveland will receive GI Genius intelligent endoscopy modules, which use artificial intelligence, as part of an award through the Medtronic Health Equity Assistance Program for colorectal cancer screening. This program, sponsored by Medtronic and Amazon Web Services, donates AI-assisted colonoscopy technology to facilities providing for medically underserved communities with either low CRC screening rates or where access to this cutting-edge technology is not currently available.

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The Center for Disease Control’s National Center for Immunization and Respiratory Diseases has awarded University Hospitals of Cleveland a sizable grant to support its assignment as a study site in the United States Flu Vaccine Effectiveness Network.

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Announcement about Randy Vince, Jr., MD, MS, joining University Hospitals (UH) in Cleveland as the inaugural Minority Men’s Health Director for UH Cutler Center for Men and as a faculty member of the system's Urology Institute and UH Seidman Cancer Center.

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University Hospitals Names Celina Cunanan as Chief Diversity, Equity & Belonging Officer

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Researchers at University Hospitals, with support from an American Heart Association® grant, will work to better understand how to successfully treat Black women diagnosed with depression who are also at risk for high blood pressure.

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Many therapeutics for asthma and other obstructive lung diseases target the β2-adrenergic receptor (β2AR), a G protein-coupled receptor (GPCR) that rapidly supports airway relaxation when stimulated. Yet, overuse of these agents is associated with adverse health outcomes, including death, which has limited their utility as frontline therapies. Now, a mouse model study published in today’s issue of Molecular Cell, from investigators at University Hospitals (UH) and Case Western Reserve University, identifies a novel strategy to isolate the beneficial effects of β2AR stimulation. This suggests a new therapeutic approach to airway diseases as well as numerous other conditions involving the aberrant function of GPCRs.

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With the support of Harrington Discovery Institute at University Hospitals (UH), an ophthalmic therapeutic dubbed KIO-301, which was initially developed by Richard Kramer, PhD, at the University of California, Berkeley (UCB), has successfully been granted approval to start a Phase 1b, first-in-human clinical trial. Currently under the stewardship of Kiora Pharmaceuticals, Inc., (NASDAQ: KPRX) via a license with UCB, Inc., the drug is intended to restore lost vision in patients with Retinitis Pigmentosa (RP)--a rare, genetic eye disease that causes severe loss of functional vision and affects an estimated 100,000 people in the U.S.

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Announcement that University Hospitals in Cleveland appointed Scott Sasser, MD, FACEP, as Chief Physician Executive and President, University Hospitals Medical Group and University Hospitals Physician Services; effective Aug. 1, 2022,

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Announcement of annual hospital ranking from US News & World Report, which recognized University Hospitals Cleveland Medical Center as a Best Hospital for 2022-2023. UH Cleveland Medical Center ranked in four of 15 adult specialties, and is ranked third among all hospitals in Ohio.

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Several hospitals in the University Hospitals health system have been recognized by the American Heart Association (AHA) for their quality stroke care. The American Heart Association/American Stroke Association’s Get With The Guidelines®-Stroke Quality Achievement Awards, achieved by UH medical centers, recognizes their commitment to ensuring stroke patients receive the most appropriate treatment according to nationally recognized, research-based guidelines based on the latest scientific evidence.

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University Hospitals Cleveland Medical Center named first SpaceOAR Hydrogel, Center of Excellence in the World

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Announcement of the American Hospital Association (AHA), the premier national trade association representing more than 5,000 hospitals and health systems, selecting University Hospitals health system as the 2022 winner of its most prestigious honor: the Quest for Quality Prize.

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n a new paper, researchers from University Hospitals (UH) detail how they used data via a dashboard to decrease the use of packed red-blood cell (pRBC) transfusions and platelets with an increase in appropriate transfusions. Their paper, “Transfusion Utilization and Appropriateness: Thinking Differently at a Tertiary Academic Medical Center,” appears in the July/August 2022 issue of the edition of the Physician Leadership Journal. (DOI: https://doi:10.55834/plj.1146877267)

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A new study from UH Harrington Heart & Vascular Institute in Cleveland further proves that people living in areas that were subjected to housing discrimination decades ago now suffer from higher rates of poor health outcomes, including heart disease, kidney failure and diabetes.

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Spicy foods are trending lately, with a booming hot sauce market and spicy food challenges happening across the world and our devices. From TikTok pepper-eating contests to “extreme” items on restaurant menus that require adventurous diners to sign liability waivers, it begs the question: Can consuming the spiciest peppers and hot sauces in the world be bad for your health? University Hospitals dietitian, Jayna Metalonis, MS, RD, LD, explores this hot topic and shares the surprising health benefits of spicy foods.

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Cleveland's University Hospitals patients with strokes are being given tenecteplase, a faster-acting drug than alteplase (tPA), which has been a mainstay since the 1990s.

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Announcement of renowned neurosurgeon Sepideh Amin-Hanjani, MD, joining University Hospitals Cleveland Medical Center as the new Director, Cerebrovascular and Skull Base Surgery. She also is Vice-Chair of the Department of Neurological Surgery at UH.

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Researchers at UH Rainbow published new findings that COVID-19 is not equivalent to flu infection for children. Among 66 pediatric ICUs in the US, the number admitted each quarter with COVID-19 or MIS-C during the first 15 months of the pandemic was twice as high as that for flu pre-pandemic.

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Harrington Discovery Institute® at University Hospitals in Cleveland, Ohio, and its registered UK charity Fund for Cures UK, Ltd. (Fund for Cures UK) have issued a call for proposals for the 2023 Harrington UK Rare Disease Scholar Award. In addition to grant funding, Harrington Discovery provides guidance and oversight in drug development, while intellectual property is retained by the scholar and their institution.

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A drug currently used in just 1% of cancers has significant potential against the remaining 99%, according to a new study from UH Seidman Cancer Center and Case Western Reserve University, published in the prestigious journal Nature Cancer. Ivosidenib, or AG-120, is currently used against cancers that have a mutation in the IDH1 gene. However, study results show that Ivosidenib is also effective against unmutated, or “wild-type” IDH1. The protein coded by the IDH1 gene in cancers helps cancer cells survive in a stressful tumor environment, so any inhibitor medication that could weaken this defense mechanism is considered a promising therapy. UH and CWRU scientists discovered that under conditions present in the tumor microenvironment, drugs previously believed to be selective for the mutant enzyme have activity against the normal protein. Specifically, low glucose and magnesium levels enhance drug activity. The team has now tested Ivosidenib in mouse models of pancreatic, colorectal, o