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Article URL:

http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1009975

Press-only preview: https://plos.io/pgen-1009975

 

Image Caption: Heat map showing five clusters of genetic variants and their proportional association estimates with nine traits.

Image Credit: Andrew J Grant (CC-BY 4.0, https://creativecommons.org/licenses/by/4.0/)

Article Title: Noise-augmented directional clustering of genetic association data identifies distinct mechanisms underlying obesity

Author Countries: United Kingdom

Funding: AJG and SB are supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (grant number 204623/Z/16/Z). DG is supported by the British Heart Foundation Research Centre of Excellence (RE/18/4/34215) at Imperial College London and a National Institute for Health Research Clinical Lectureship (CL-2020-16-001) at St. George’s, University of London. PDWK is supported by the UK Medical Research Council (MC_UU_00002/13). This research was funded by the NIHR Cambridge Biomedical Research Centre (BRC-1215-20014). The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. For the purpose of open access, the author has applied a CC-BY public copyright licence to any Author Accepted Manuscript version arising from this submission. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing interests: I have read the journal’s policy and the authors of this manuscript have the following competing interests. DG is employed part-time by Novo Nordisk. The other authors declare no competing interests.

Journal Link: PLOS Genetics

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