Feature Channels: Drug Resistance

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Newswise: Hospitals Can Reduce Antibiotic Overuse by Avoiding Unnecessary Blood Draws in Critically Ill Children, Study Shows
Released: 2-May-2022 11:05 AM EDT
Hospitals Can Reduce Antibiotic Overuse by Avoiding Unnecessary Blood Draws in Critically Ill Children, Study Shows
Johns Hopkins Medicine

A Johns Hopkins Children’s Center-led national quality improvement collaborative highlights a “less is more” method that may prevent antibiotic overprescribing

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26-Apr-2022 12:35 PM EDT
New Model for Antibacterial Mechanism: Toxic Misinformation
Brookhaven National Laboratory

Biologists have discovered an aberrant protein that’s deadly to bacteria. The discovery could help scientists unravel the lethal mechanism of certain antibiotics—and potentially point the way to future antibacterial drugs.

Newswise: Study Reveals Genetic Diversity of a Particularly Problematic Pathogen
Released: 27-Apr-2022 3:55 PM EDT
Study Reveals Genetic Diversity of a Particularly Problematic Pathogen
University of California San Diego Health

Researchers at UC San Diego have used a systems biology approach to parse the genetic diversity of Clostridioides difficile, a particularly problematic pathogen, particularly in health care settings.

Released: 25-Apr-2022 2:05 PM EDT
Offspring weakens, when parents are given antibiotics
University of Southern Denmark

Antibiotics have once proclaimed the salvation of the world. Today, researchers fear that antibiotics could become a threat to public health and the natural environment.

Released: 25-Apr-2022 11:05 AM EDT
US study suggests COVID-19 pandemic may be accelerating antimicrobial resistance
European Society of Clinical Microbiology and Infectious Diseases

Among those hospitalised during the pandemic, both COVID-19 patients and those tested for SARS-COV-2 but negative, had higher rates of antibiotic-resistant bacterial infections compared to patients hospitalised before the pandemic, according to a study evaluating the pandemic’s impact on antimicrobial resistance (AMR) in 271 hospitals across the USA, to be presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Lisbon, Portugal (23-26 April).

Released: 21-Apr-2022 3:05 PM EDT
Scientists use machine learning to identify antibiotic resistant bacteria that can spread between animals, humans and the environment
University of Nottingham

Experts from the University of Nottingham have developed a ground-breaking software, which combines DNA sequencing and machine learning to help them find where, and to what extent, antibiotic resistant bacteria is being transmitted between humans, animals and the environment.

Released: 19-Apr-2022 5:50 PM EDT
New study on mice sheds light on the anti-obesity effects of vitamin E
Shibaura Institute of Technology

Over the past few decades, obesity has become increasingly common throughout the entire world.

Newswise: Targeting “Cell Clustering” by Gene Deletion Reduces Drug Resistance
Released: 15-Apr-2022 7:05 AM EDT
Targeting “Cell Clustering” by Gene Deletion Reduces Drug Resistance
Stony Brook University

A recent study published in the journal Communications Biology shows manipulating and deleting a specific gene (AMN1) from yeast could provide a foundation for a new approach to combatting drug resistance when treating microbial infections or cancer.

Released: 14-Apr-2022 9:00 AM EDT
NIH Grant Awarded to Study HIV Drug-Resistant Genetic Mutations Across Africa
Institute of Human Virology at the University of Maryland School of Medicine

University of Maryland School of Medicine (UMSOM)’s Institute of Human Virology (IHV) researchers received funding from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases (NIAID) for $2.7 million to study genetic changes in two genes from the HIV-1 virus that may make it resistant to antiretroviral therapy.

7-Apr-2022 3:25 PM EDT
From Rare Soil Microbe, a New Antibiotic Candidate
Washington University in St. Louis

Demand for new kinds of antibiotics is surging, as drug-resistant and emerging infections are becoming an increasingly serious global health threat. Researchers are racing to reexamine certain microbes that serve as one of our most successful sources of therapeutics: the actinomycetes.

Newswise: Microbiology expert advocates for One Health approach to tackling antibiotic resistance globally
Released: 8-Apr-2022 1:05 PM EDT
Microbiology expert advocates for One Health approach to tackling antibiotic resistance globally
University of California, Irvine

Dr. Oladele "Dele" Ogunseitan, UC Presidential Chair and Professor of Population Health and Disease Prevention at the University of California, Irvine Program in Public Health, discusses using a One Health approach to combating global antibiotic resistance.

Newswise: How a narrow-spectrum antibiotic takes aim at C. Diff
Released: 6-Apr-2022 2:00 PM EDT
How a narrow-spectrum antibiotic takes aim at C. Diff
Rockefeller University

Most antibiotics are double-edged swords. Besides killing the pathogen they are prescribed for, they also decimate beneficial bacteria and change the composition of the gut microbiome.

Released: 5-Apr-2022 3:55 PM EDT
The latest news on clinical trials is here on Newswise
Newswise

Here are some of the latest articles that have been added to the Clinical Trials channel on Newswise.

Released: 29-Mar-2022 2:55 PM EDT
妙佑医疗国际研究发现纳米孔测序法可快速检测和鉴定抗生素耐药性微生物
Mayo Clinic

有越来越多人因抗生素耐药性感染而面临死亡。此类感染是微生物物种通过突变以躲避制药破坏性攻击所引发的。仅2019年,全球便有超过120万人死于抗生素耐药性感染。

Released: 29-Mar-2022 2:50 PM EDT
أبحاث مايو كلينك تُظهر أن أسلوب تسلسل الثقوب النانوية يكتشف ويحدد الميكروبات المقاومة للمضادات الحيوية بسرعة
Mayo Clinic

مدينة روتشستر، ولاية مينيسوتا- يموت عدد متزايد من الناس بسبب العَدوى المقاومة للمضادات الحيوية. وهذه العَدوى تغذيها أنواع الميكروبات التي تتحور لتتجنب الأدوية المطورة بهدف تدميرها. توفي أكثر من 1.2 مليون شخص حول العالم في عام 2019 بسبب العَدوى المقاومة للمضادات الحيوية.

Released: 29-Mar-2022 1:45 PM EDT
Pesquisa da Mayo Clinic mostra que método de sequenciamento por nanoporos detecta e identifica rapidamente micróbios resistentes a antibióticos
Mayo Clinic

Cada vez mais pessoas estão morrendo por infecções resistentes a antibióticos. Essas infecções são alimentadas por espécies microbianas que estão em mutação para escapar das drogas desenvolvidas para destruí-las.

Released: 29-Mar-2022 1:35 PM EDT
El método de secuenciación de nanoporos detecta e identifica rápidamente microbios resistentes a antibióticos, demuestra estudio de Mayo Clinic
Mayo Clinic

Una creciente cantidad de personas muere debido a infecciones resistentes a los antibióticos. Estas infecciones son propiciadas por especies bacterianas que mutan a fin de evadir a los fármacos creados para destruirlas.

Newswise: Drug-resistant bacteria flaunt their curves
Released: 15-Mar-2022 11:45 AM EDT
Drug-resistant bacteria flaunt their curves
Osaka University

If you’ve been hitting the gym and getting results, you know it’s time to strut your stuff; and it turns out bacteria feel the same way.

Newswise: Hospital-affiliated doctors prescribe fewer antibiotics through telehealth than third-party physicians
Released: 8-Mar-2022 10:05 AM EST
Hospital-affiliated doctors prescribe fewer antibiotics through telehealth than third-party physicians
Michigan Medicine - University of Michigan

A new study found that for telemedicine visits related to acute respiratory infection, contractor-supplied physicians prescribed antibiotics to patients nearly twice as often as emergency physicians employed by the hospital system. As the majority of acute respiratory infections are viral, researchers say the findings highlight concerns of antibiotic stewardship amid growing antibiotic resistance.

Released: 1-Mar-2022 4:45 PM EST
Genome Refolding Contributes to Cancer Therapy Resistance, Penn Study Finds
Perelman School of Medicine at the University of Pennsylvania

While gene mutations can lead to drug resistance, researchers in the Perelman School of Medicine at the University of Pennsylvania have identified an important, non-genetic adaptation that could also drive resistance to targeted therapy in T cell leukemia, a type of blood cell cancer.

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Released: 1-Mar-2022 10:10 AM EST
Fungal infections cost U.S. $6.7B in a year
University of Georgia

New research from the University of Georgia found that fungal infections account for $6.7 billion in health care spending in 2018. And that’s just the cases that were directly responsible for inpatient hospital stays.

Newswise: The protective armour of superbug C.difficile revealed
Released: 25-Feb-2022 1:45 PM EST
The protective armour of superbug C.difficile revealed
Newcastle University

The spectacular structure of the protective armour of superbug C.difficile has been revealed for the first time showing the close-knit yet flexible outer layer – like chain mail.

Released: 24-Feb-2022 3:05 PM EST
Machine Learning Antibiotic Prescriptions Can Help Minimize Resistance Spread
American Technion Society

Using genomic sequencing techniques and machine learning analysis of patient records, Israeli researchers have developed an antibiotic prescribing algorithm that cuts the risk of emergence of antibiotic resistance by half.

17-Feb-2022 3:35 PM EST
The Latest Research News in Cardiovascular Health
Newswise

The Latest Research News in Cardiovascular Health

Newswise: Protein structure offers clues to drug-resistance mechanism
Released: 18-Feb-2022 12:50 PM EST
Protein structure offers clues to drug-resistance mechanism
Massachusetts Institute of Technology (MIT)

MIT chemists have discovered the structure of a protein that can pump toxic molecules out of bacterial cells. Proteins similar to this one, which is found in E. coli, are believed to help bacteria become resistant to multiple antibiotics.

Newswise: Elsa U. Pardee Foundation and National Cancer Institute Fund Leukemia Research at TTUHSC El Paso
Released: 17-Feb-2022 12:00 PM EST
Elsa U. Pardee Foundation and National Cancer Institute Fund Leukemia Research at TTUHSC El Paso
Texas Tech University Health Sciences Center El Paso

Texas Tech University Health Sciences Center El Paso has received more than a quarter-million dollars to study the proteins that contribute to disease progression and drug resistance in acute myeloid leukemia.

Newswise: New UNC Charlotte research center to drive pandemic preparedness and prevention
Released: 9-Feb-2022 1:50 PM EST
New UNC Charlotte research center to drive pandemic preparedness and prevention
University of North Carolina at Charlotte

The key to preventing another global pandemic may be found at UNC Charlotte. Expanding upon the University’s award-winning development of a novel COVID-19 wastewater surveillance program and rapidly growing success in bioinformatics, the University is bringing together experts to explore ways to combat threats to human health.

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Released: 8-Feb-2022 12:20 PM EST
Agricultural fungicides may be driving antimicrobial resistance
University of Georgia

New research from the University of Georgia has shown, for the first time, that compounds used to fight fungal diseases in plants are causing resistance to antifungal medications used to treat people.

Newswise: Ludwig Cancer Research Study Identifies Potential Vulnerability in Drug-Resistant Neuroblastoma
Released: 7-Feb-2022 12:45 PM EST
Ludwig Cancer Research Study Identifies Potential Vulnerability in Drug-Resistant Neuroblastoma
Ludwig Cancer Research

A Ludwig Cancer Research study has identified a potential vulnerability in neuroblastoma tumors that might be exploited to improve treatment of the aggressive childhood cancer, which accounts for roughly 15% of all deaths from pediatric malignancies.

Released: 4-Feb-2022 11:20 AM EST
Shorter Treatment is Better for Young Children with Outpatient Pneumonia
Vanderbilt University Medical Center

Five days of antibiotics is superior to 10 days for children with community-acquired pneumonia who are not hospitalized, according to a study published in JAMA Pediatrics.

Released: 26-Jan-2022 1:45 PM EST
The latest news in Behavioral Science for media
Newswise

Here are some of the latest articles we've posted in the Behavioral Science channel.

Released: 24-Jan-2022 3:40 PM EST
The Latest Research News from the Health Disparities Channel
Newswise

The latest research news from the Health Disparities Channel.

Released: 20-Jan-2022 3:45 PM EST
What Is Combination Drug Therapy?
Tufts University

Using drugs in synergistic combinations may clear infections more efficiently and slow the acquisition of drug resistance. Bree Aldridge of Tufts University School of Medicine explains how researchers find the right drug cocktails, slowing AMR, and the role artificial intelligence can have in both.

Newswise: New Tool Assesses Evolutionary Risks of Antibiotics
Released: 19-Jan-2022 1:30 PM EST
New Tool Assesses Evolutionary Risks of Antibiotics
University of California San Diego

Countering a rising antibiotic resistance crisis, doctors now prescribe combinations of antibiotics. Yet many risks are involved with such multi-drug combinations. Scientists have developed a way to help doctors evaluate outcomes for different drug pairs and boost the odds of successful treatment.

Newswise: Scientists prove that deadly gene has jumped from a harmless organism to a nasty pathogen
Released: 17-Jan-2022 5:05 PM EST
Scientists prove that deadly gene has jumped from a harmless organism to a nasty pathogen
University of South Australia

Australian scientists have made a surprising discovery in the origins of an antibiotic-resistant gene previously thought to have been confined to Adelaide.

Newswise: Sanford Burnham Prebys researchers awarded $3.6 million to study antibiotic resistance
Released: 13-Jan-2022 5:35 PM EST
Sanford Burnham Prebys researchers awarded $3.6 million to study antibiotic resistance
Sanford Burnham Prebys

Sanford Burnham Prebys professor Andrei Osterman, Ph.D., has been awarded a $3.6 million grant from the National Institutes of Health (NIH) to expand current knowledge of antibiotic resistance, which will inform more precise antibiotic prescribing practices and help researchers develop drugs that are harder for bacteria to resist.

Newswise: Unlocking the secrets of a critical schistosomiasis drug
Released: 6-Jan-2022 12:00 PM EST
Unlocking the secrets of a critical schistosomiasis drug
Texas Biomedical Research Institute

For decades, no one really knew how the drug praziquantel treated a parasitic disease afflicting more than 200 million people around the world. Now, two independent teams of researchers have found the answer, which could help lead to improved treatments that support the W.H.O.’s goal of eliminating Schistosomiasis as a public health problem by 2025.

Newswise: Plasma-Based Engineering Creates Contact-Killing, Antifouling, Drug-Release Surfaces
Released: 4-Jan-2022 10:05 AM EST
Plasma-Based Engineering Creates Contact-Killing, Antifouling, Drug-Release Surfaces
American Institute of Physics (AIP)

Conventional wet-chemistry methods used to create biocidal materials are complex, time-consuming, and expensive. In the Journal of Applied Physics, researchers present a tutorial in which they explore a promising alternative called plasma-enabled surface engineering. The technology relies on nonequilibrium plasma that produces chemical reactions to change the properties at the material surface. Reactions can be manipulated by adjusting electric power for surface activation, coating deposition, and surface nanostructuring of virtually any solid material.

Released: 28-Dec-2021 1:40 PM EST
CDC Awards $2 Million to Penn to Combat Antimicrobial Resistance in Southern Africa
Perelman School of Medicine at the University of Pennsylvania

More than $2 million in grants from the U.S. Centers for Disease Control and Prevention (CDC) will allow a Penn Medicine team to further develop infrastructure and clinical capacity to address antimicrobial resistance and infectious diseases in Botswana.

Newswise: UCLA Jonsson Comprehensive Cancer Center study details chromosome-level changes that allow melanomas to develop drug resistance
Released: 20-Dec-2021 2:55 PM EST
UCLA Jonsson Comprehensive Cancer Center study details chromosome-level changes that allow melanomas to develop drug resistance
University of California, Los Angeles (UCLA), Health Sciences

UCLA Jonsson Comprehensive Cancer Center researchers led the development of a melanoma model of drug resistance, enabling them to study structures and dynamics resulting in intrachromosomal and extrachromosomal changes that support resistance in cancer cells.

Newswise: Pet Scans Help Guide Drug to Best Treat Orthopaedic Implant Bacterial Infections
Released: 16-Dec-2021 11:20 AM EST
Pet Scans Help Guide Drug to Best Treat Orthopaedic Implant Bacterial Infections
Johns Hopkins Medicine

Treating bacterial infections associated with orthopaedic implants has often been a case of too little, too late. The traditional therapy has been a combination of prolonged antibiotics, including rifampin, a 50-year-old drug that has been a staple in the global fight against tuberculosis and other bacterial diseases.

Released: 15-Dec-2021 4:10 PM EST
Researchers first to predict when bacteria may become resistant to antibiotics
University College London

Scientists have spotted signs of ‘pre-resistance’ in bacteria for the first time – signs that particular bacteria are likely to become resistant to antibiotics in the future – in a new study led by UCL and Great Ormond Street Hospital researchers.

Released: 13-Dec-2021 4:40 PM EST
New resistance-busting antibiotic combination could extend the use of ‘last-resort’ antibiotics
University of Oxford

Scientists have discovered a new potential treatment that has the ability to reverse antibiotic resistance in bacteria that cause conditions such as sepsis, pneumonia, and urinary tract infections.

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Released: 30-Nov-2021 3:20 PM EST
Ohio State takes 'One Health' approach to identify antibiotic-resistant bacteria
Ohio State University Wexner Medical Center

With the knowledge that human, animal and environmental health are intertwined, researchers at five of The Ohio State University’s colleges and its medical center are uniquely positioned to collaborate on a “one health” approach to battle antibiotic resistance and prevent the next global health crisis.

Released: 30-Nov-2021 1:35 PM EST
Single-cell sequencing and bioinformatic tools applications discussed in Research Review
Sbarro Health Research Organization (SHRO)

Nowadays, single-cell RNA sequencing technologies and related bioinformatics tools are emerging as essential devices for dissecting tumors at single-cell resolution and understanding carcinogenesis and drug response mechanisms, representing a turning point in cancer research.

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Released: 23-Nov-2021 1:25 PM EST
Ultrashort-pulse lasers kill bacterial superbugs, spores
Washington University in St. Louis

Researchers at Washington University School of Medicine in St. Louis have found that multidrug-resistant bacteria and bacterial spores can be killed by ultrashort-pulse lasers. The findings could lead to new ways to sterilize wounds and blood products without damaging human cells.

Released: 17-Nov-2021 10:10 AM EST
New group of antibacterial molecules identified
Karolinska Institute

Researchers at Karolinska Institutet, Umeå University, and the University of Bonn have identified a new group of molecules that have an antibacterial effect against many antibiotic-resistant bacteria.


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