Scientists have identified a crucial gene, CsMIKC1,that controls the number of flowering sites in Cannabis sativa, a finding that could significantly enhance both medicinal and grain yields. The study reveals how CsMIKC1 drives inflorescence development, offering new pathways to boost productivity in Cannabis cultivation.
Cancer cells appear to hijack a genetic pathway involved in DNA repair to drive malignancy and overcome treatment, a study led by UT Southwestern Medical Center researchers shows. Their findings, published in Cell, explain how chromosomes in some tumors undergo massive rearrangements and could lead to new strategies to avoid cancer drug resistance.
Researchers at the University of Michigan Health Rogel Cancer Center have uncovered a key reason why a typically normal protein goes awry and fuels cancer. They found the protein NSD2 alters the function of the androgen receptor, an important regulator of normal prostate development.
The vision of people with a rare inherited condition that causes them to lose much of their sight early in childhood was 100 times better after they received gene therapy to address the genetic mutation causing it. Some patients even experienced a 10,000-fold improvement in their vision after receiving the highest dose of the therapy, according to researchers from the Perelman School of Medicine at the University of Pennsylvania who co-led the clinical trial published in The Lancet.
About 8 to 10 million Americans over age 40 have an overabundance of cloned white blood cells, or lymphocytes, that hamper their immune systems. Although many who have this condition — called monoclonal B-cell lymphocytosis (MBL) — do not experience any symptoms, a new study shows they may have an elevated risk for several health complications, including melanoma, a form of skin cancer.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
The new approach marks a major step forward in the design of AI tools to support clinical decisions in cancer diagnosis, therapy. The model uses features of a tumor’s microenvironment to forecast how a patient might respond to therapy and to help inform individualized treatments.
A research team created seven learning models using Support Vector Machine (SVM) algorithms to discern flowering-time-associated genes (FTAGs) from non-FTAGs, with the SVM-Kmer-PC-PseAAC model performing the best (F1 score = 0.934, accuracy = 0.939, and receiver operating characterstic = 0.943).
A research team conducted a comprehensive analysis of phylogenetic relationships among Australian citrus species and 13 international accessions, shedding light on their genetic diversity and evolutionary history.
The National Science Foundation (NSF) has funded University of Illinois Urbana-Champaign research that aims to connect the dots between quantitative and molecular genetics and improve crop breeding.
Scott Holmes of Camilla, Georgia, is a senior nursing major at Georgia Southern University. This summer he became the South Georgia campus' first participant in PCOM's Pathways to Medicine Undergraduate Research program.
Assistant Professor of Pharmaceutical Sciences Kuo-Ching (KC) Mei from Binghamton University, State University of New York and his team have won the $1.9M Maximizing Investigators’ Research Award (MIRA) for Early Stage Investigators (ESI) from the National Institute of General Medical Sciences to tackle gene therapy challenges.
New research from Memorial Sloan Kettering Cancer Center (MSK) uses cryo-electron microscopy to shed new light on the ubiquitin; could help predict the risk of blood clots in cancer patients; reveals why micronuclei burst, accelerating aggressive cancers; and surveys healthcare providers about the benefits and risks of commercial genetic testing.
FAU has received a five-year NIH grant to further research on designing and applying statistical methods to identify regions of the genome affected by natural selection, which is an important evolutionary force that enables humans to adapt to new environments and fight disease-causing pathogens.
Advancing the frontiers of agricultural genetics, a newly developed eight-way tomato Multiparental advanced generation intercross (MAGIC) population serves as a rich genetic resource that unlocks diverse traits from wild tomato species.
A new study has mapped the genetic makeup of mango, revealing its genomic diversity and population structure that influence key agronomic traits. The research identifies genetic differentiation among mango populations and discovers candidate genes linked to flowering, fruit weight, and aroma compounds, essential for advancing mango breeding through genomic-assisted methods.
Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.
Scientists have unveiled a revolutionary protospacer adjacent motif (PAM)-less genome editing system using CRISPR-SpRY, marking a major advancement in soybean breeding. This innovative method eliminates the traditional PAM sequence constraints, enabling precise editing at specific loci.
New study reveals how an unexpected genetic mechanism influences the evolution of butterfly wing coloration.
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