Scientists have identified a gene involved in cell metabolism and energy production that is overactive in a deadly form of brain cancer known as glioblastoma, according to a study at Washington University School of Medicine in St. Louis. The findings suggest that inhibiting that gene may improve the outlook for glioblastoma patients.
There are many important events in a person’s life, including weddings, graduations, school dances and job interviews. The clothing industry has long profited from these events and the special clothing they require. However, according to new research from the University of Missouri, approximately 30 million Americans living with mobility challenges and impairments lack the appropriate clothing required for social engagements, work and exercise. Following this new study researchers suggest that apparel manufacturers could play a vital role in helping people navigate social barriers by providing more accessible clothing options.
A researcher at Missouri University of Science and Technology wants to scrap the traditional electronic and paper survey approaches to gathering marketing and information systems data in favor of scanning your brainwaves.
How do you remember what happened today in the weeks and months that follow? Researchers at the Stowers Institute for Medical Research have answered a piece of that question in a recent study.
Research from Saint Louis University finds that male and female same-sex partnered patients fail to identify as such in medical records and that failure may contribute to poorer health outcomes.
On Giving Tuesday, holiday donation campaigns launch into high gear, with various year-end appeals supporting a whole array of causes. But how do people decide where to donate their money? They know that they should give to the neediest cases, but new research from Washington University in St. Louis’s Olin Business School shows the donation decision often comes down to something called a “charity beauty premium.
One out of every six American women has experienced a sexual assault or an attempted sexual assault or rape in her lifetime, according to the National Institute of Justice and the Centers for Disease Control and Prevention. While more than half of female survivors of rape report symptoms of post-traumatic stress disorder (PTSD), previous research has found that not all survivors respond to traditional treatments for PTSD, causing their symptoms to resurface over time. Abigail Rolbiecki, Ph.D., a researcher at the University of Missouri School of Medicine, says that photovoice interventions, where participants express their thoughts and feelings through photos, combined with traditional PTSD treatments, could result in a more complete recovery for survivors of sexual assault.
The island of Madagascar off the coast of Africa was largely unexplored seismically until recently. The first broadband seismic images of the island help solve a longstanding mystery: why are there volcanoes far from any tectonic boundary?
Patients with the most lethal form of acute myeloid leukemia (AML) – based on genetic profiles of their cancers – typically survive for only four to six months after diagnosis, even with aggressive chemotherapy. But new research indicates that such patients, paradoxically, may live longer if they receive a milder chemotherapy drug.
Scientists at Washington University in St. Louis isolated an enzyme that controls the levels of two plant hormones simultaneously, linking the molecular pathways for growth and defense. Similar to animals, plants have evolved small molecules called hormones to control key events such as growth, reproduction and responses to infections.
The parasite that causes river blindness infects about 37 million people in parts of Africa and Latin America, causing blindness and other major eye and skin diseases in about 5 million of them. A study from Washington University School of Medicine in St. Louis sheds light on the genetic makeup of the parasite, a step toward the goal of eradication.
Private speech is a good thing for a child’s cognitive development; however, it may be important that children monitor and repair errors in their speech, even when talking to themselves. Louis Manfra, assistant professor in the College of Human Environmental Sciences at the University of Missouri, found that children do, in fact, monitor their speech for errors, even without a listener. Manfra says parents and caregivers might encourage preschool-aged children to monitor their private speech by demonstrating such behavior in their own aloud private speech.
A combination of two topical drugs that have been in use for years triggers a robust immune response against precancerous skin lesions, according to a new study. The research, from Washington University School of Medicine in St. Louis and Harvard Medical School, shows that the therapy activates the immune system’s T cells, which then attack the abnormal skin cells.
Carrying extra weight increases a person's risk that a benign blood disorder will develop into multiple myeloma, a blood cancer. This is particularly true for older, African-American men.
With the holidays right around the corner, families are planning meals and trips to spend time with loved ones. With the food and travel, it is easy for exercise schedules to become disrupted. Steve Ball, associate professor of nutrition and exercise physiology at the University of Missouri, says that to prevent holiday weight gain, people need to focus on consistency and set realistic goals for exercise.
An engineer at Washington University in St. Louis discovered a model in which the mechanics of the cells’ environment can predict their movement, a finding that ultimately could mean confining cell transition in tumors and potentially making cancer “a substantially less deadly disease,” said the lead researcher.
Striking racial divides in the 2016 election serve as a reminder that racially charged narratives still have a powerful hold on the American mindset. If the left is to compete in future elections, it must learn to tell competing narratives that build coalitions around racial justice, says political scholar Clarissa Hayward.
This is the campus where, through historic debates, presidential and vice presidential candidates make their bones or make their exits. This is the campus where the democratic process is more than an exercise; it’s a point of unity, pride, leadership, scholarship, research, life.So at such a transformative moment in history, when America’s “Brexit vote” came to pass, where better than Washington University in St.
Ten graduates of Missouri University of Science and Technology were honored as Missouri S&T’s 2016 Alumni of Influence during a special event Saturday, Nov. 5, at Hasselmann Alumni House on the Missouri S&T campus.
A computer scientist at Washington University in St. Louis has developed a way to coax cells to do natural things under unnatural circumstances, which could be useful for stem cell research, gene therapy and biofuel production.Michael Brent, the Henry Edwin Sever Professor of Engineering in the School of Engineering & Applied Science, has designed an algorithm, called NetSurgeon, that recommends genes to surgically remove from a cell’s genome to force it to perform a normal activity in a different environment or circumstance.
A new technique to cheaply and rapidly create sets of DNA fragments that include all possible genetic variants will help scientists distinguish between genetic variants linked to disease and those that are innocuous.
While employee salaries and wages can account for up to 80 percent of the total operating budget in health care organizations, human resources departments in many U.S. hospitals still rely on traditional, bureaucratic HR practices that can constrain employee effort and initiative. Now, researchers at the University of Missouri School of Medicine have identified three HR practices for hospitals that can improve clinical work behaviors, leading to better outcomes for patients.
Researchers at Washington University School of Medicine in St. Louis and Vanderbilt University School of Medicine have identified a human antibody that prevents, in pregnant mice, the fetus from infection and the placenta from damage. The antibody also protects adult mice from Zika disease.
The discarded bone of a chicken leg, still etched with teeth marks from a dinner thousands of years ago, provides some of the oldest known physical evidence for the introduction of domesticated chickens to the continent of Africa, research from Washington University in St. Louis has confirmed.Based on radiocarbon dating of about 30 chicken bones unearthed at the site of an ancient farming village in present-day Ethiopia, the findings shed new light on how domesticated chickens crossed ancient roads — and seas — to reach farms and plates in Africa and, eventually, every other corner of the globe.
Researchers have developed a chemical compound that detects the Alzheimer’s protein amyloid beta better than current FDA-approved agents. The compound potentially could be used in brain scans to identify the signs of Alzheimer’s early, or to monitor response to treatment.
Inflammation is one of the main reasons why people with diabetes experience heart attacks, strokes, kidney problems and other, related complications. Now, in a surprise finding, researchers at Washington University School of Medicine in St. Louis have discovered, in mice, that when certain immune cells can’t manufacture fat, the mice don’t develop diabetes and inflammation, even when consuming a high-fat diet.
The American Physical Society and the American Institute of Physics this month awarded the 2017 Dannie Heineman Prize for Mathematical Physics to Carl M. Bender of Washington University in St. Louis. Here he explains the work that won the prize
A new study shows that Zika targets the male reproductive system, at least in mice. Three weeks after Zika infection, male mice had shrunken testicles, low levels of sex hormones and reduced fertility. The results suggest that Zika infection may interfere with men’s ability to have children.
Scientists at Washington University School of Medicine in St. Louis have shown that supplementing healthy mice with a natural compound called NMN can compensate for the loss of energy production that is typical of aging. Older NMN-supplemented mice showed improved energy metabolism, reducing typical signs of aging such as gradual weight gain, loss of insulin sensitivity and declines in physical activity.
Salmonella has a unique characteristic that allows the bacteria to penetrate through cell barriers and replicate inside its host. Now, scientists at the Cancer Research Center and the University of Missouri have developed a non-toxic strain of Salmonella to penetrate and target cancer cells. Results from this study could lead to promising new treatments that actively target and control the spread of cancer.
State actions to regulate retail sales of tobacco nearly doubled between 2012 and 2014, according to new research from the Brown School at Washington University in St. Louis, but much of that activity involved e-cigarettes, perhaps the least harmful tobacco product.Researchers surveyed tobacco-control officials from 48 states in 2012 and again in 2014 to determine the extent of their policy activity at the retail level.
In a serendipitous moment, scientists studying light sensing molecules in plants have discovered that they are also temperature sensors.The discovery may eventually allow them to design crop varieties that are better able to cope with a warming world.
A faculty member at Washington University in St. Louis’ School of Engineering & Applied Science has been awarded two separate grants worth a combined $2.5 million to develop better biomedical imaging tools.Mark Anastasio, professor of biomedical engineering, will use a four-year, $2.2 million grant from the National Institutes of Health (NIH) to create a new X-ray technique that will assist engineers as they develop new bioengineered tissues.
Researchers, led by scientists at Washington University School of Medicine in St. Louis, have identified areas in the brains of children with Tourette’s syndrome that appear markedly different from the same areas in the brains of children who don’t have the neuropsychiatric disorder.
Charcot-Marie-Tooth disease is an untreatable inherited disorder that leads to loss of motor neurons and paralysis. Now, scientists at Washington University School of Medicine in St. Louis and Stanford University have designed compounds to correct the molecular dysfunction underlying the disease.
There is no basis in logic or fact to the claims by Donald Trump and some of his surrogates that this year’s presidential election is rigged against Trump, says an election law expert at Washington University in St. Louis.Trump’s argument focuses on three concerns, said Greg Magarian, professor of law: “Those are in-person voter fraud, cheating by local election officials and conspiratorial adverse press coverage.
Scientists, led by a team of researchers at Washington University School of Medicine in St. Louis, have linked mutations in a single gene to autism in people who have a rare tumor syndrome typically diagnosed in childhood. The findings, in patients with neurofibromatosis type 1 (NF1), may lead to a better understanding of the genetic roots of autism in the wider population.
According to new research from the University of Missouri, minimal exercise may be all it takes for postmenopausal women to better regulate insulin, maintain metabolic function and help prevent significant weight gain. These findings suggest that women can take a proactive approach and may not need to increase their physical activity dramatically to see significant benefits from exercise.