Feature Channels: Stem Cells

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Released: 23-Aug-2022 12:00 PM EDT
Golgi-dependent Reactivation and Regeneration of Quiescent Neural Stem Cells
Preprints

Mahekta Rajeshkumar Gujar, Yang Gao, Xiang Teng, Qiannan Deng, Ye Sing Tan, Yusuke Toyama, Hongyan Wang

Newswise: Untapped potential of stem cells could aid repair of spinal cord damage
Released: 22-Aug-2022 3:15 PM EDT
Untapped potential of stem cells could aid repair of spinal cord damage
Francis Crick Institute

Scientists at the Francis Crick Institute have identified a group of latent stem cells that respond to injury in the central nervous system of mice.

Released: 22-Aug-2022 12:00 PM EDT
Human Embryonic Stem Cell-derived Cerebral Organoids for Treatment of Mild Traumatic Brain Injury in a Mouse Model
Preprints

Jong-Tae Kim, Sung Min Cho, Dong Hyuk Youn, Tae Yeon Kim, Sung Woo Han, Chan Hum Park, Younghyurk Lee, Eun Pyo Hong, Harry Jung, Jae Jun Lee, Jong Kook Rhim, Jeong Jin Park, Jun Hyong Ahn, Heung Cheol Kim,

Released: 22-Aug-2022 12:00 PM EDT
Transplantation of human umbilical cord mesenchymal stem cells induces angiogenesis and promotes repair of uterine scars in rats
Preprints

Xiuyin Shen, Xin Luo, Shuzhen Wu, Yingchun Wan, Huiting Ma, Shaoxin Ye, Zhuoling Zhang, Min Lu, Hai Tang, Xiaoyan Gou, Xiaoling Guo, ZhengPing Liu

Released: 22-Aug-2022 12:00 PM EDT
Cortical interneuron development is affected in leukodystrophy 4H
Preprints

Stephanie Dooves, Liza M.L. Kok, Dwayne B. Holmes, Nicole Breeuwsma, Marjolein Breur, Marianna Bugiani, Nicole Wolf, Vivi M Heine

Released: 22-Aug-2022 12:00 PM EDT
A nationwide survey of late effects in survivors of juvenile myelomonocytic leukemia in Japan
Preprints

Shuichi Ozono, Kazuo Sakashita, Nao Yoshida, Harumi Kakuda, Kenichiro Watanabe, Miho Maeda, Yasushi Ishida, Atsushi Manabe, Takashi Taga, Hideki Muramatsu

Released: 22-Aug-2022 12:00 PM EDT
Differentiation of human induced pluripotent stem cells into cortical neural stem cells
Preprints

Alexandra Neaverson, Malin H.L. Andersson, Osama A. Arshad, Luke Foulser, Mary Goodwin-Trotman, Adam Hunter, Ben Newman, Minal Patel, Charlotte Roth, Tristan Thwaites, Helena Kilpinen, Matthew E. Hurles, Andrew Day, Sebastian S. Gerety

Released: 22-Aug-2022 12:00 PM EDT
Induced pluripotent stem cell-derived dendritic cell vaccine therapy genetically modified on the ubiquitin-proteasome system
Preprints

Shinta Tominaga, Toshiyasu Ojima, Motoki Miyazawa, Hiromitsu Iwamoto, Junya Kitadani, Shimpei Maruoka, Keiji Hayata, Hiroki Yamaue

17-Aug-2022 4:35 PM EDT
The Locked Library: Disease Causes Cells to Reorder Their DNA Incorrectly
Perelman School of Medicine at the University of Pennsylvania

With super-resolution imaging, Penn Medicine researchers discovered that cells change the physical structure of their genome when they’re affected by disease

Released: 20-Aug-2022 12:00 PM EDT
Molecular evolution and inheritance pattern of Sox gene family among Bovidae
Preprints

Mabel O Akinyemi, Muyiwa S Adegbaju, Anastasia Grytsay, Osamede H Osaiyuwu, Jessica Finucan, Ibukun M Ogunade, Sunday O Peters, Bolaji N Thomas, Olanrewaju B Morenikeji

Released: 19-Aug-2022 12:00 PM EDT
Lipidomic profiling reveals age-dependent changes in complex plasma membrane lipids that regulate neural stem cell aging
Preprints

Xiaoai Zhao, Xin Yan, Kévin Contrepois, Francesco Vallania, Mathew Ellenberger, Chloe M. Kashiwagi, Stephanie D. Gagnon, Cynthia J. Siebrand, Matias Cabruja, Gavin M. Traber, Andrew McKay, Daniel Hornburg, Purvesh Khatri, Michael P.

Released: 19-Aug-2022 12:00 PM EDT
NANOGP1, a tandem duplicate of NANOG, exhibits partial functional conservation in human naive pluripotent stem cells
Preprints

Katsiaryna Maskalenka, Gokberk Alagoz, Felix Krueger, Joshua Wright, Maria Rostovskaya, Asif Nakhuda, Adam Bendall, Christel Krueger, Simon Walker, Aylwyn Scally, Peter Rugg-Gunn

Released: 19-Aug-2022 12:00 PM EDT
Hematopoietic Stem Cell Gene Therapy Alleviates Disease Phenotypes in a Murine Model of Danon Disease
Preprints

Chao Chen, Sherin Hashem, Jay Sharma, Ana Maria Manso, Paul Bushway, Jason Duran, Emily Gault, Yusu Gu, Jose Cano Nigenda, Angel Soto-Hermida, Kirk Peterson, Paul Saftig, Stephanie Cherqui, Sylvia Evans,

Released: 18-Aug-2022 3:55 PM EDT
Immune cell model paves way for new treatments targeting common infection amongst immunocompromised children
Murdoch Childrens Research Institute

Researchers have successfully engineered human immune cells to model an infection common among immunocompromised people in a breakthrough discovery, paving the way for new drug testing and treatments.

Released: 18-Aug-2022 12:00 PM EDT
Gilteritinib-induced severe immune-related enteritis: a possible case report
Preprints

Pan Luo, Huiyin Qiu, Yushan Yang, Jiaqi Wu, Xianmin Song, Guorong Fan, Gaolin Liu, Junwei Gao

Released: 18-Aug-2022 12:00 PM EDT
Mesenchymal stromal cell encapsulation in uniform chitosan beads using microchannel emulsification
Preprints

Dongjin S Shin, Francesco K Touani, Damon G.K Aboud, Anne Kietzig, Sophie Lerouge, Corinne A Hoesli

Released: 18-Aug-2022 12:00 PM EDT
Loss of LRP1 in adult neural stem cells impairs migration to ischemic lesions
Preprints

Kristi Dietert, Swetha Mahesula, Sheetal Hegde, John Verschelde, Pamela Reed, Shane Sprague, Erzsebet Kokovay, Naomi L Sayre

Newswise: Why We Fit A Mini Brain with a Mini Cap
14-Aug-2022 2:05 PM EDT
Why We Fit A Mini Brain with a Mini Cap
 Johns Hopkins University

It could be the world’s tiniest EEG electrode cap, created to measure activity in a brain model the size of a pen dot. Its designers expect the device to lead to better understanding of neural disorders and how potentially dangerous chemicals affect the brain. This engineering feat, led by Johns Hopkins University researchers and detailed today in Science Advances, expands what researchers can accomplish with organoids, including mini brains—the lab-grown balls of human cells that mimic some of a brain’s structure and functionality.

Released: 17-Aug-2022 12:00 PM EDT
Deriving Schwann Cells from hPSCs Enables Disease Modeling and Drug Discovery for Diabetic Peripheral Neuropathy
Preprints

Homa Majd, Sadaf Amin, Zaniar Ghazizadeh, Andrius Cesiulis, Edgardo Arroyo, Karen Lankford, Sina Farahvashi, Angeline K Chemel, Mesomachukwu Okoye, Megan D Scantlen, Jason Tchieu, Elizabeth L Calder, Valerie LeRouzic, Abolfazl Arab,

Released: 17-Aug-2022 12:00 PM EDT
Media for culturing cells v1
Preprints

Rebecca Berrens

Newswise: Cell Mapping Close to the Bone
Released: 16-Aug-2022 4:05 PM EDT
Cell Mapping Close to the Bone
King Abdullah University of Science & Technology (KAUST)

Tissues contain many different cell types, and it remains challenging to understand how they interact and contribute to tissue function.

Released: 16-Aug-2022 2:05 PM EDT
Many paths are open to neurons born early
University of Bonn

When it comes to royalty, things are clear: The monarch's first child inherits the crown. Siblings born later must make do with a less glamorous profession.

Released: 16-Aug-2022 12:00 PM EDT
Collagen Ⅰ-DDR1 signaling promotes hepatocellular carcinoma cell stemness via Hippo signaling repression.
Preprints

Yi-Xiao Xiong, Xiaochao Zhang, Jing-Han Zhu, Yuxin Zhang, Yonglong Pan, Yu Wu, Jian-Ping Zhao, Junjie Liu, Yuan-Xiang Lu, Huifang Liang, Zhanguo Zhang, Wanguang Zhang

Released: 16-Aug-2022 12:00 PM EDT
Fludarabine/TBI 8 Gy versus fludarabine/treosulfan conditioning in patients with AML in first complete remission: A Study from the Acute Leukemia Working Party of the EBMT
Preprints

Gesine Bug, Myriam Labopin, Riitta Niittyvuopio, Matthias Stelljes, Christian Reinhardt, Inken Hilgendorf, Nicolaus Kroeger, Ain Kaare, Wolfgang Bethge, Kerstin Schaefer-Eckart, Mareike Verbeek, Stephan Mielke, Kristina Carlson, Ali

Released: 16-Aug-2022 12:00 PM EDT
Bone Regeneration by Hydroxyapatite-Gelatinnanocomposites
Preprints

Sahar I Mostafa, Nesma M Abdelfattah, Sayed M Ghorab, Manal F Osman, Noha A Elwassefy

Released: 16-Aug-2022 12:00 PM EDT
Mass spectrometry imaging reveals early metabolic priming of cell lineage in differentiating human induced pluripotent stem cells
Preprints

Arina A. Nikitina, Alexandria Van Grouw, Tanya Roysam, Danning Huang, Facundo M. Fernandez, Melissa L. Kemp

Released: 15-Aug-2022 12:00 PM EDT
Directed differentiation of mouse pluripotent stem cells into functional lung-specific mesenchyme
Preprints

The successful generation of endodermal, ectodermal, and most mesodermal lineages from pluripotent stem cells has resulted in basic discoveries and regenerative medicine clinical trials of cell-based therapies.

Released: 15-Aug-2022 12:00 PM EDT
Alcam-a and Pdgfr-α are essential for the development of sclerotome derived stromal cells that support hematopoiesis in vivo.
Preprints

: Mesenchymal stromal cells are essential components of hematopoietic stem and progenitor cell (HSPC) niches, regulating HSPC proliferation and fate decisions.

Released: 15-Aug-2022 12:00 PM EDT
Mechanical force sensing drives extrusion of Enterovirus A71-infected cells from colonic epithelial organoids
Preprints

Jasmine Moshiri, Ailsa Craven, Sara Mixon, Manuel Amieva, Karla Kirkegaard

Released: 15-Aug-2022 12:00 PM EDT
Mesenchymal stem cells transplantation combined with IronQ attenuates ICH-induced inflammation response via Mincle/Syk signaling pathway
Preprints

Guoqiang Yang, Jiraporn Kantapan, Maryam Mazhar, Xue Bai, Yuanxia Zou, Honglian Wang, Bingfeng Huang, Sijing Yang, Nathupakorn Dechsupa, Li Wang

Released: 15-Aug-2022 12:00 PM EDT
Lipids Maintain Genomic Stability and Developmental Potency of Murine Pluripotent Stem Cells
Preprints

Liangwen Zhong, Miriam Gordillo, Xingyi Wang, Yiren Qin, Yuanyuan Huang, Alexey Soshnev, Ritu Kumar, Gouri Nanjangud, Daylon James, C. David Allis, Todd Evans, Bryce Carey, Duancheng Wen

Released: 12-Aug-2022 12:00 PM EDT
Peripherally Inserted Central Venous Catheter for Pediatric Hematologic Diseases; A Retrospective 11-year Single-center Experience.
Preprints

Silvio Ligia, Salvatore Giacomo Morano, Francesca Kaiser, Alessandra Micozzi, Maria Luisa Moleti, Walter Barberi, Fiorina Giona, Antonio Chistolini, Valentina Arena, Alfonso Piciocchi, Maurizio Forgione, Giulia Gasperini, Marco Fabbri, Anna Maria Testi

Released: 12-Aug-2022 12:00 PM EDT
Effect of human breast milk-derived exosomes on the migration and inflammatory response of lipopolysaccharide-exposed dental pulp stem cells
Preprints

Ehsaneh Azaryan, Samira Karbasi, Mansoore Saharkhiz, Mohammad Yahya Hanafi-Bojd, Asghar Zarban, Fariba Emadian Razavi, Mohsen Naseri

Released: 11-Aug-2022 2:45 PM EDT
Large number of stem cell lines carry significant DNA damage, say researchers
University of Cambridge

DNA damage caused by factors such as ultraviolet radiation affect nearly three-quarters of all stem cell lines derived from human skin cells, say Cambridge researchers, who argue that whole genome sequencing is essential for confirming if cell lines are usable.

Released: 11-Aug-2022 12:00 PM EDT
Deciphering transcriptional networks during human cardiac development
Preprints

Robin Canac, Bastien Cimarosti, Aurore Girardeau, Virginie Forest, Pierre Olchesqui, Jeremie Poschmann, Richard Redon, Patricia Lemarchand, Nathalie Gaborit, Guillaume Lamirault

Released: 11-Aug-2022 12:00 PM EDT
Human model of primary carnitine deficiency cardiomyopathy reveals ferroptosis as a novel disease mechanism
Preprints

Malte Loos, Birgit Klampe, Thomas Schulze, Xiaoke Yin, Konstantinos Theofilatos, Bärbel Ulmer, Carl Schulz, Charlotta Behrens, Tessa Van Bergen, Eleonora Adami, Henrike Maatz, Michaela Schweizer, Susanne Brodesser, Boris Skryabin,

Released: 11-Aug-2022 12:00 PM EDT
Development of lacrimal gland organoids from iPSC derived multizonal ocular cells
Preprints

Melis Asal, Gamze Koçak, Vedat Sarı, Tuba Reçber, Emirhan Nemutlu, Canan Aslı Utine, Sinan Guven

Released: 11-Aug-2022 12:00 PM EDT
Exercise Training Remodels Adipocyte-Specific Extracellular Matrix Proteins and Alters Innervation and Vascularization in Inguinal White Adipose Tissue (iWAT)
Preprints

Pasquale Nigro, Maria Vamvini, Jiekun Jackie Yang, Tiziana Caputo, Li-Lun Ho, Danae Papadopoulos, Nicholas Philip Carbone, Royce Colin, Jie He, Hirshman Frederick Michael, Joseph Daniel White, Jacques Robidoux, Robert Hickner, Soeren



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