An injury to the anterior cruciate ligament (ACL) can lead to severe osteoarthritis in both animal and human patients. Now, a new interdisciplinary study on the protein that lubricates our joints says that lubricant may actually be a precursor of joint disease.
Scientists have estimated that the age of an individual does not indicate how likely they are to be infected by SARS-CoV-2. However, development of symptoms, progression of the disease, and mortality are age-dependent.
A team of researchers at the University of Chicago have developed a self-assembling nanoparticle to create a toolbox for treating infections such as Toxoplasma gondii, a serious parasitic infection.
A team of psychologists at the Universities of Sussex and Portsmouth have purr-fected the art of building a bond with cats.
Both old wives’ tales and psychological literature posit that spouses’ faces become more similar over time. Scholars have argued that partners tend to occupy the same environments, engage in the same activities, eat the same food, and mimic each other’s emotions—and as these factors can also influence facial appearance—their faces should converge with time. For example, if the partners smile a lot—and make each other smile—they should co-develop similar smile lines.
Oral cancer is more likely to spread in patients experiencing high levels of pain, according to a team of researchers at NYU College of Dentistry that found genetic and cellular clues as to why metastatic oral cancers are so painful.
A team of psychologists at the Universities of Sussex and Portsmouth have purr-fected the art of building a bond with cats.
Columbia Engineering researchers report that Sofosbuvir-terminated RNA is more resistant to the proofreader of SARS-CoV-2, the virus that causes COVID-19, than Remdesivir-terminated RNA. The results of the new study, published today by the Nature Research journal Scientific Reports, support the use of the FDA-approved hepatitis C drug EPCLUSA—Sofosbuvir/Velpatasvir—in combination with other drugs in COVID-19 clinical trials.
Numerous animals may be vulnerable to SARS-CoV-2, the virus that causes Covid-19, according to a large study modelling how the virus might infect different animals' cells, led by UCL researchers. The study, published in Scientific Reports, reports evidence that 26 animals regularly in contact with people may be susceptible to infection. The researchers investigated how the spike protein from SARS-CoV-2 could interact with the ACE2 protein it attaches to when it infects people. The focus of the investigation was whether mutations in the ACE2 protein in 215 different animals, that make it different from the human version, would reduce the stability of the binding complex between the virus protein and host protein. Binding to the protein enables the virus to gain entry into host cells; while it is possible the virus might be able to infect animals via another pathway, it is unlikely based on current evidence that the virus could infect an animal if it cannot form a stable binding
Forecasting the spreading of a pandemic is paramount in helping governments to enforce a number of social and economic measures, apt at curbing the pandemic and dealing with its aftermath.
New light is being shed on a little-known role of Y chromosome genes, specific to males, that could explain why men suffer differently than women from various diseases, including Covid-19.
A collaborative team of researchers from the United Kingdom and the Beaumont Research Institute in Royal Oak, Michigan have been awarded more than $1.67 million by the National Institute on Aging, a division of the U.S. National Institutes of Health, to study the link between dementia and post-operative delirium.
Researchers have sequenced the genome of Alexander Fleming's penicillin mould for the first time and compared it to later versions.
Lee Gettler, associate professor of anthropology at Notre Dame, led a team that worked with the BaYaka and Bondongo societies in the Republic of the Congo.
How a second wave of COVID-19 infections may evolve across Europe over the next few months, using data on infection rates and travel within and between European countries, is modelled in a Scientific Reports paper.
As extreme weather and other events increase in frequency and intensity, cybercriminals ramp up attacks on technologies that tie together urban infrastructure systems, networks critical to the flow of data, people, goods, and services must be made more resilient to failure, according to a team of scientists.
The reactive and piecemeal approach historically used to manage beaches in Hawai'i has failed to protect them.
Researchers have shown there may be key genetic differences in the causes of attention-deficit hyperactivity disorder (ADHD) between African Americans and people of European ancestry, which may play an important part in how patients of different ethnic backgrounds respond to treatments for this condition.
In research with key ramifications for women of childbearing age, findings by Oregon State University scientists show that embryos produced by vitamin E-deficient zebrafish have malformed brains and nervous systems.
Researchers at the University of Helsinki have developed a technique in which a computer models visual perception by monitoring human brain signals.
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