Androgens stimulate prostate cancer cells to grow. Researchers have discovered a new function of the AR in prostate cells — the AR is imported into and localizes to mitochondria of the cell, where it plays a novel role in regulating multiple mitochondrial processes.
For the first time, scientists have identified compounds found in coffee which may inhibit the growth of prostate cancer. This is a pilot study, carried out on drug-resistant cancer cells in cell culture and in a mouse model;
The Cancer Prevention and Research Institute of Texas (CPRIT) has awarded UT Southwestern Medical Center more than $18.4 million for cancer research and faculty recruitment.
UNLV study examines firsthand accounts of new fathers’ experiences with PPD, how it differs from that of women, and how to best remove barriers they face in receiving diagnoses and treatment of the little-known phenomenon.
New research by scientists at the University of Nottingham suggests that environmental contaminants found in the home and diet have the same adverse effects on male fertility in both humans and in domestic dogs.
Scientists from Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified how prostate cancer transforms into a deadly treatment-resistant subtype following treatment with anti-androgen therapy. Their findings—which include the metabolic rewiring and the epigenetic alteration that drives this switch— reveal that an FDA-approved drug holds potential as a NEPC treatment. The research also uncovers new therapeutic avenues that could prevent this transformation from occurring. The study was published in Cancer Cell.
Some patients with metastatic prostate cancer respond to a combination of immune checkpoint inhibitors after hormonal therapy and chemotherapy have failed, according to early results from a clinical trial led by investigators at MD Anderson
New research suggests that the relationship between physical and brain fitness varies in older adults by virtue of their sex. The study is published ahead of print in the Journal of Applied Physiology.
Investigators at Rutgers Cancer Institute of New Jersey have found that a surgical procedure, when used as a first-line therapy for a form of testicular cancer known as seminoma, is associated with favorable survival rates.
When normal cells grow, divide or do any job in the body, they do so in response to a whole slew of internal sensors that measure nutrients and energy supply, and environmental cues that inform what happens outside the cell.
Many men with low-risk prostate cancer who most likely previously would have undergone immediate surgery or radiation are now adopting a more conservative “active surveillance” strategy, according to an analysis of a new federal database by scientists from Dana-Farber Cancer Institute.
Current tools used to predict prostate cancer progression are generally subjective in nature, leading to differing interpretations among clinicians
In what they consider a surprise finding, Johns Hopkins Medicine researchers have demonstrated a key role for male sex hormone “signaling” in inducing—rather than suppressing—allergic lung inflammation in a mouse model of asthma.
To make it easier for patients to receive world-class cancer care, UC San Diego Health has added a new multidisciplinary cancer clinic in Hillcrest and expanded its infusion center for both oncology patients and others in need of infusion services.
A new $1.7 million grant from the National Cancer Institute will enable researchers at the University of Illinois at Chicago to study the fruit and its potential as a treatment for prostate cancer.
A recent study has found that a specific gene in cancerous prostate tumors indicates when patients are at high-risk for the cancer to spread, suggesting that targeting this gene can help patients live longer.
Manish Kohli, M.D., has joined Moffitt Cancer Center as the vice chair of the Department of Genitourinary Oncology. He also has an extensive research background, focusing on creating new ways to bring individualized care to patients.
People with cancer are more than four times more likely to commit suicide than people without cancer, according to Penn State College of Medicine researchers.
Alterações genéticas no câncer de próstata de baixo risco, diagnosticado por biópsia com agulha, podem identificar homens que são portadores de câncer nas glândulas prostáticas com risco maior, segundo descoberta feita pela Mayo Clinic. A pesquisa, publicada na edição de janeiro da Mayo Clinic Proceedings, descobriu pela primeira vez que alterações genéticas associadas ao câncer de próstata de risco intermediário e alto também podem estar presentes em alguns casos de câncer de próstata de baixo risco.
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