Health care personnel who received a two-dose regimen of Pfizer–BioNTech vaccine had an 89% lower risk for symptomatic illness than those who were unvaccinated. For those who received the two-dose regimen of the Moderna vaccine, the risk was reduced by 96%.
Cinco de los sistemas de salud sin fines de lucro más grandes del condado de Los Ángeles incluyendo hospitales, clínicas e instalaciones en toda la región, anunciaron la campaña más reciente para su coalición bettertogether.health.
A UCLA study reveals new insights into the wiring of a major brain circuit that is attacked by Parkinson’s and Huntington’s disease. The findings could hone scientists’ understanding of how diseases arise in the human brain and pinpoint new therapeutic targets.
Cesarean birth rates are on the rise, and this is especially true for high-risk pregnant women who have undergone organ transplantation. While cesarean births account for 31% of all deliveries in the United States, the rate of cesarean births for pregnant people with kidney transplants is 62.6% and 44.6% for liver transplants.
LA's five most prominent health systems remain united to save lives, pivoting resources to unveil a multi-media public service education campaign to convince those avoiding care during the pandemic to get back to their health
A UCLA study suggests that many physicians may not have the knowledge or training to properly recognize how Lyme disease appears on the skin of Black patients.
Dr. Alice Soragni of the UCLA Jonsson Comprehensive Cancer Center has received a $2.5 million grant from the National Cancer Institute to develop lab-grown mini tumors that can help identify treatments for rare types of neuroendocrine cancer.
An inexpensive anti-seizure medication markedly improves learning and memory and other cognitive functions in Alzheimer’s patients who have epileptic activity in their brains, according to a study published in the Sept. 27th issue of JAMA Neurology.
A new $13.3 million contract from the National Institutes of Health’s Rapid Acceleration of Diagnostics initiative, or RADx, will enable the UCLA SwabSeq lab to expand its capacity to process thousands of COVID-19 tests a day.
Patients with dementia who had signs and risk factors of a pulmonary embolism, or a blood clot in the lungs, were much less likely to be tested for pulmonary embolism than patients without dementia who had the same signs and risk factors.
Early results from a UCLA-led clinical trial found treating women with estrogen receptor (ER)-positive and human epidermal growth factor receptor-2 (HER2)-negative early breast cancers with a novel type of anti-hormonal therapy, called an oral selective estrogen receptor degrader (SERD), led to clinically meaningful reductions in tumor activity prior to surgery.
A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center has found that treating women with HER2 positive metastatic breast cancer with the HER2-targeting antibody-drug conjugate trastuzumab deruxtecan (T-DXd) significantly prolongs the length of time the disease is controlled and cancer growth is halted when compared to the current standard of care, trastuzumab emtansine (T-DM1).
A paper detailing the method that led to the US Food and Drug Administration approval for PSMA PET imaging, which was led by UCLA and UCSF and their nuclear medicine teams, was recently published in JAMA Oncology.
Physicians prescribed opioids more often to their white patients who complained of new-onset low back pain than to their Black, Asian and Hispanic patients during the early days of the national opioid crisis, when prescriptions for these powerful painkillers were surging but their dangers were not fully apparent.
Some medical procedures can put health care workers at higher risk for contracting COVID-19 and other respiratory diseases. With these high-risk procedures, it’s important that health care providers have access to personal protective equipment (PPE), including N95 masks. However, not all procedures that may seem high risk have that designation.
A new study from scientists at the UCLA Jonsson Comprehensive Cancer Center found that emerging drugs that activate the protein STING, a well-established regulator of immune cell activation, substantially alter the activity of metabolic pathways responsible for generating the nucleotide building blocks for DNA.
Researchers at UCLA Health have been awarded $3 million from the Governor’s Office of Planning and Research (OPR) to develop a statewide stress surveillance system and establish a network of physicians/scientists to study how stress impacts the body and what can be done to increase resiliency.
People who are prescribed the anti-coagulant apixaban cite six major reasons for failing to adhere to their prescriptions, including cost and potential bleeding.
Physicians and scientists from UCLA will be joining thousands of urology experts on Sept. 10 to Sept. 13 for the virtual American Urological Association (AUA) Annual Meeting.
The troubling news and images emerging from Afghanistan as American troops withdraw from the region after 20 years is causing a spike in post-traumatic stress among veterans at home, says UCLA Health psychiatrist Bruce Kagan, MD, PhD.
Scientists Dr. Cristina Puig-Saus and Dr. Daniel Shin from the UCLA Jonsson Comprehensive Cancer Center have received a $1 million Translational Research Award from the U.S. Department of Defense Melanoma Research Program to help advance the use of chimeric antigen receptor, or CAR, T cell therapy as a treatment for people with acral, mucosal and uveal melanomas.
A new preclinical study led by researchers at the UCLA Jonsson Comprehensive Cancer Center suggests that treating people who have aggressive cancers, including melanoma, pancreatic and colorectal cancers, with immune checkpoint inhibitors, quickly followed with mutation-targeted therapy, can help overcome treatment resistance and help people live longer.
UCLA researchers have successfully grown restorative brain cells in large batches suitable for transplantation in patients. The therapy is designed to repair damage to the brain from white matter stroke, a “silent stroke” that can kick off years of cognitive deterioration and can accelerate Alzheimer’s disease. A new paper is published in the journal Stem Cell Research.
The risk that both tobacco and electronic cigarettes can pose to regular smokers’ health has been well documented, but a new UCLA study illustrates just how quickly vaping can affect the cells of even healthy younger nonsmokers.
Emergency department physicians who saw patients with a pulmonary embolism—a blood clot in the lung—were about 15% likelier over the next 10 days to test subsequent patients for the same thing.
Women with frequent urinary tract infections say they’re unhappy with what they perceive as their doctors’ overuse of antibiotics and with the limited treatment options available to them, according to a study led by researchers from UCLA and Cedars-Sinai.
A research team from the UCLA Youth Stress and Mood Program at UCLA's Jane and Terry Semel Institute for Neuroscience and Human Behavior has been approved to lead a $13 million funding award by the Patient-Centered Outcomes Research Institute (PCORI) to compare two evidence-based interventions for reducing suicide attempts and improving patient outcomes for youth presenting to emergency departments.
New UCLA-led research indicates that simple text messages emphasizing the easy availability of COVID-19 vaccines successfully boosted the number of people who got the shot.
Researchers from UCLA and Cedars-Sinai have developed a new way to detect a potentially life-threatening condition that can occur during pregnancy. The condition, placenta accreta spectrum disorder, occurs when the placenta grows too deeply into the uterine wall and fails to detach from the uterus after childbirth. It can lead to significant blood loss during pregnancy and delivery, requiring blood transfusions and intensive care, and it can result in serious illness and infection and can even be fatal for the mother. The condition occurs in less than 0.5% of pregnancies.
Removing a protein that is often overexpressed in a rare and aggressive subtype of leukemia can help to slow the cancer’s development and significantly increase the likelihood of survival, according to a study in mice led by scientists at the UCLA Jonsson Comprehensive Cancer Center.
Internationally renowned physician-scientist Dr. Beth Karlan, director of cancer population genetics at the UCLA Jonsson Comprehensive Cancer Center, is being honored with the Lifetime Achievement Award from the International Gynecologic Cancer Society (IGCS) for her contributions to gynecologic cancer research and clinical practice.
Findings could help pave the way for cancer therapies that target TAF12, potentially stopping transcription in cancer cells and helping decrease the growth of cancerous tumors.
A chemical modification that occurs in some RNA molecules as they carry genetic instructions from DNA to cells’ protein-making machinery may offer protection against non-alcoholic fatty liver, a condition that results from a build-up of fat in the liver and can lead to advanced liver disease, according to a new study by UCLA researchers. The study, conducted in mice, also suggests that this modification — known as m6A, in which a methyl group attaches to an RNA chain — may occur at a different rate in females than it does in males, potentially explaining why females tend to have higher fat content in the liver. The researchers found that without the m6A modification, differences in liver fat content between the sexes were reduced dramatically.
A new prognostic tool helps predict which men with advanced metastatic prostate cancer will respond favorably to a novel targeted therapy.
Dr. Elizabeta Nemeth, professor of medicine and director of the Center for Iron Disorders at the David Geffen School of Medicine at UCLA, has been awarded the 2021 William Dameshek Prize by the American Society of Hematology (ASH) for her contributions to the field of hematology.
Men with high-risk prostate cancer with at least one additional aggressive feature have the best outcomes when treated with multiple healthcare disciplines, known as multimodality care, according to a UCLA study.
A UCLA-led study comparing brain cells known as astrocytes in humans and mice found that mouse astrocytes are more resilient to oxidative stress, a damaging imbalance that is a mechanism behind many neurological disorders.
UCLA Health is proud to present an online pride celebration and drag revue featuring iconic drag performers Ongina, Moi Moi Moi, Sunset Blush and others, each of whom will lip sync a song promoting community, inclusion and diversity.
UCLA Health will receive a $4.8 million grant from The National Institutes of Health to develop methods that will improve genetic risk estimates – polygenic risk scores – for specific diseases in people from diverse populations and mixed ancestries.
UCLA researchers discover MAOIs could activate immune system to shrink various types of tumors
A new study shows that tai chi mirrors the beneficial effects of conventional exercise by reducing waist circumference in middle-aged and older adults with central obesity.
A new multi-institution study led by a team of researchers at the David Geffen School of Medicine demonstrated that blocking a protein called ABCB10 in liver cells protects against high blood sugar and fatty liver disease in obese mice. ABCB10 activity also prompted insulin resistance in human liver cells.
UCLA Health has received a $750,000 grant from the U.S. Economic Development Administration to scale healthcare innovations for COVID-19 response and recovery and to support health equity through BioFutures, a new LA County workforce development program for diversity in the biosciences.
A team of researchers from UCLA, Cedars-Sinai and the Cystic Fibrosis Foundation has developed a first-of-its-kind molecular catalog of cells in healthy lungs and the lungs of people with cystic fibrosis. The findings could help scientists in their search for specific cell types that represent prime targets for genetic and cell therapies for cystic fibrosis.
Current guidelines for managing osteoporosis specifically call out hip or spine fractures for increasing the risk for subsequent bone breaks. But a new UCLA-led study suggests that fractures in the arm, wrist, leg and other parts of the body should also set off alarm bells.A fracture, no matter the location, indicates a general tendency to break a bone in the future at a different location.
The combination approach uses immune checkpoint inhibitors with ATRA, a safe medication that is widely used to treat leukemia.
Johnese Spisso, president of UCLA Health and CEO of UCLA Hospital System, has joined forces with nine other U.S. health system leaders to form the CEO Coalition and set new safety standards for the nation’s health care workers.
A UCLA-led study shows that physicians frequently order preventive medical services for adult Medicare beneficiaries that are considered unnecessary and of “low value” by the U.S. Preventive Services Task Force — at a cost of $478 million per year.
Patients with advanced colorectal cancer may be spared from a toxic side effect caused by a type of targeted therapy used to treat the cancer with the help of another drug normally used to treat melanoma, according to a study led by researchers at the UCLA Jonsson Comprehensive Cancer Center and Memorial Sloan Kettering Cancer Center.
The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, has added SAB-185, a polyclonal antibody therapy, to the COVID-19 outpatient treatment study.
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