Children and adolescents who receive integrated mental health and medical treatment are 66 percent more likely to have a good outcome than those who receive more traditional primary care.
High-grade serous ovarian cancer often responds well to the chemotherapy drug carboplatin, but why it so frequently comes back after treatment has been a medical mystery. Now a team of UCLA researchers has discovered that a subset of tumor cells that don’t produce the protein CA125, a biomarker used to test for ovarian cancer, has an enhanced ability to repair their DNA and resist programmed cell death — which allows the cells to evade the drug and live long enough to regrow the original tumor.
A wealth of programs target autistic kids. But what about when they grow up? UCLA's Program for the Education and Enrichment of Relational Skills is the only evidence-based approach to teaching social skills to young adults with autism.
The UCLA department of neurosurgery ranks No. 2 in the nation in scholarly research, according to a recent paper evaluating the impact of published articles in the field.
A study by the Los Angeles County Trauma Consortium has found that compliance with Brain Trauma Foundation guidelines for treating traumatic brain injury do not necessarily lead to lower mortality rates.
For the first time, UCLA researchers have shown that a natural protein fragment produced in the brain can act as an inhibitor of a key enzyme implicated in the onset of Alzheimer’s disease, a finding that could lead to the development of new drugs to treat the disease.
Findings are the first to shed light on the genetic differences between DiGeorge syndrome patients with autism and those with psychosis.
UCLA Health and One Legacy honor organ, eye and tissue donors
UCLA scientists have discovered a groundbreaking experimental therapy that has the ability to suppress the development of ulcerative colitis (UC), a disease which causes inflammation in the digestive tract and colon cancer. The treatment utilizes a chemical inhibitor able to block an RNA molecule (microRNA-214) involved in the transmission of genetic information.
An assessment tool developed jointly by psychiatrists at UCLA and the University of Texas, Houston will be the first to help identify maladaptive grief in youth between 8 and 18.
UCLA’s Jonsson Comprehensive Cancer Center is ranked among the top 10 cancer centers in the nation, according to a U.S. News & World Report survey of board-certified physicians from across the country. The survey reviewed patient outcomes, the cancer center’s reputation among physicians, mortality rates and other care-related factors.
UCLA Health’s hospitals have been named to U.S. News and World Report’s 2015-2016 Best Hospitals Honor Roll. UCLA, which previously ranked No. 5 in the country, tied for No. 3 this year.
•UCLA scientists have for the first time demonstrated the importance of sodium-dependent glucose transporters (SGLTs) in delivering glucose to pancreatic and prostate cancer cells •Study results show promising evidence that current SGLT inhibitor drugs (such as those commonly used to treat diabetes) could potentially be used to block glucose uptake and reduce tumor growth in these cancers •Researchers also utilized PET imaging to measure SGLT activity, suggesting the technology could be used to better diagnose pancreatic and prostate cancers •Pancreatic and prostate cancers are among the most deadly forms of cancer in men, and new therapies are urgently needed to combat these diseases
Why do some youngsters bounce back quickly from a traumatic brain injury, while others suffer for years? New UCLA/USC research suggests that damage to the coating around the brain’s nerve fibers--not injury severity-- may explain the difference.
A physical education program that brings commercial-grade fitness equipment to under-resourced schools, along with a curriculum based on boosting confidence and making participation more enjoyable, dramatically increases students’ performance on California’s standardized physical fitness test, a UCLA study has found.
Though the ACA created several national initiatives to reduce hospital readmissions for heart attacks and congestive heart failure, there is nothing for sepsis, a potentially life-threatening illness caused by infection. Yet it costs the health care system more than both combined.
Monitoring men with very low- and low-risk prostate cancers using watchful waiting or active surveillance, called expectant management, is a useful approach for a large number of men with localized tumors and could spare them the debilitating side effects of aggressive treatments that are too often unnecessarily used in this patient population, a UCLA review of common practices in prostate cancer has found.
A 44-year-old woman has received a successful heart transplant at Ronald Reagan UCLA Medical Center, thanks to an experimental Total Artificial Heart designed for smaller patients. The UCLA patient is the first person in California to receive the smaller Total Artificial Heart, and the first patient in the world with the device to be bridged to a successful heart transplant.
In the first study of its kind, UCLA and United Kingdom researchers found that neurons in a specific brain region play a key role in rapidly forming memories about every day events, a finding that may result in a better understanding of memory loss and new methods to fight it in Alzheimer’s and other neurological diseases.
UCLA doctors used a 3-D model of a patient’s heart to guide a tricky minimally-invasive valve replacement. UCLA patient Richard Whitaker was not a candidate for traditional surgery due his heart's unique anatomy and previous surgeries. Doctors practiced with the 3-D heart model before the actual procedure to make sure the valve would fit, which it did! Richard is now back to work after having the procedure and looking forward to planning a trip to Europe.
A new study by UCLA scientists has found that women diagnosed with breast cancer and treated with a one-week regimen of partial breast radiation after the surgical removal of the tumor, or lumpectomy, saw no increase in cancer recurrence or difference in cosmetic outcomes compared to women who received radiation of the entire breast for a period of up to six weeks after surgery. The study is one of the largest ever done on partial breast irradiation.
Chronic disease and mental health issues disproportionately affect low-income African-Americans, Latinos and Hispanics. Researchers at UCLA have developed a screening tool that may provide better treatment.
New research offers further evidence that cocaine use disrupts the immune system, making people who use it more likely to become infected with HIV.
The UCLA Medical Group has again earned the highest rating possible in an annual survey conducted by CAPG, an association representing physician organizations in 38 states, Washington, D.C., and Puerto Rico. UCLA earned five stars in the report, which assesses health care systems’ tools for delivering better patient experience and better population health, as well as overall affordability.
U.S. News and World Report has recognized Mattel Children’s Hospital UCLA for excellence in nine specialties in the 2015-16 Best Children’s Hospitals rankings.
Using functional magnetic resonance imaging, a team of UCLA researchers has shown for the first time that children with autism spectrum disorder (ASD) who are overly sensitive to sensory stimuli have brains that react differently than those with the disorder who don’t respond so severely to noises, visual stimulation and physical contact.
Wounded Warrior Project has approved a $15.7 million grant over three years for UCLA Health to expand its Operation Mend program to create a new, intensive structured treatment program for service members who have suffered mild traumatic brain injury and post-traumatic stress disorder.
A portable, finger-probe device successfully measured liver function in brain dead adult organ donors, a finding that could change the way organs are assessed and save thousands of dollars per transplant, a UCLA study has found.
Researchers and public health officials have looked for ways to better understand the health concerns of transgender populations, so social "big data" technologies like Twitter offer an untapped rich source of information that they can use for the benefit of these communities
Few doctors are prescribing a low-cost drug that has been proven effective in preventing the onset of diabetes. New research finds that only 3.7 percent of U.S. adults with pre-diabetes were prescribed metformin during a recent three-year period.
Now, parents share their arduous and “circuitous” journey to get referrals for pediatric epilepsy surgery once their child’s disease stops responding to anti-seizure medications. The UCLA study sheds light on the difficulties parents face obtaining specialty and sub-specialty care for their children during an already stressful time.
Women who experience extreme morning sickness during pregnancy are three times more likely to have children with developmental issues, including attention disorders and language and speech delays, than woman who have normal nausea and vomiting, a UCLA study has found.
A UCLA-led study on improving stroke care was selected by the Clinical Research Forum (CRF) as one of the 10 most outstanding research papers written by teams from across the nation in 2014.
Only 9 percent of U.S. academic medical practices have procedures for connecting patients to LGBT-competent physicians, and only 4 percent had policies for identifying those physicians. In addition, only 15 percent had lists of LGBT-competent physicians.
77 percent of California primary care and specialty physicians understand the basics of the Patient Protection and Affordable Care Act and 59 percent support it. Also, 525 doctors surveyed believe ACA will steer the country’s health care in the right direction.
A new UCLA study takes another step toward the early understanding of a degenerative brain condition called chronic traumatic encephalopathy, or CTE, which affects athletes in contact sports who are exposed to repetitive brain injuries. Using a new imaging tool, researchers found a strikingly similar pattern of abnormal protein deposits in the brains of retired NFL players who suffered from concussions.
Research suggests that HIV induces age-associated changes to the DNA, which in turn lead to earlier onset of age-related illnesses such as some cancers, renal and kidney disease, frailty, osteoporosis and neurocognitive diseases by more than 14 years.
a team of UCLA researchers has shown for the first time in a large cohort of patients that electroconvulsive therapy (ECT), sometimes referred to as shock treatment, change certain areas of the brain that play a role in how people feel, learn and respond to positive and negative environmental factors.
Most children with HIV who have low levels of a key immune cell eventually recover levels of this cell after they begin treatment.
UCLA professor argues that insuring undocumented Latinos under the Affordable Care Act would, in the long run, be less expensive and provide better care.
Results of a new study by UCLA researchers has found that a groundbreaking new triple combination therapy shows promising signs of more effectively controlling advanced melanoma than previous BRAF + MEK inhibitor or BRAF inhibitor + immunotherapy combos alone, and with increased immune response and fewer side effects.
UCLA researchers have for the first time described cost across an entire care process for a common condition called benign prostate hyperplasia (BPH) using time-driven activity-based costing. They found a 400 percent discrepancy between the least and most expensive ways to treat the condition.
UCLA researcher Dr. Patricia Ganz is key collaborator with Apple to develop iPhone app that empowers women to be partners in research study. App will track five common consequences of breast cancer treatment: fatigue, cognitive difficulties, sleep disturbances, mood changes and a reduction in exercise performance. Share the Journey is available to all women, not only breast cancer survivors, between the ages of 18 and 80 who live in the United States.
UCLA Health System and the Sound Body Sound Mind Foundation have formed a partnership to provide practical ways to combat childhood obesity and promote healthy lifestyles in Los Angeles.
Commentary provides evidence that the degree of income inequality can lead to a long list of health issues.
An on-board air filtration system developed specifically for school buses reduces exposure to vehicular pollutants by up to 88 percent, according to a study by researchers at the UCLA Fielding School of Public Health.
UCLA researchers have found that radiation therapy is the most common treatment for men with prostate cancer regardless of the aggressiveness of the tumor, risk to the patient and overall patient prognosis. These findings lay the groundwork for improved treatment assessment by physicians and to better inform men fighting the disease.
Two of the nation’s top eye institutes have united in an affiliation that will improve patients’ access to leading vision specialists.
Latinos are one of the fastest growing ethnic groups in the United States, with their numbers having risen 243 percent since 1980. Yet the number of Latino physicians per 100,000 Latinos has declined by 22 percent during that period.
In the first study of its kind, a consortium led by UCLA physicians found that paramedics can start medications for patients in the first minutes after onset of a stroke. While the specific drug tested, magnesium sulfate, did not improve patient outcomes, the research has resulted in a new method to get promising treatments to stroke patients quickly.
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